Outcomes of allogeneic transplant in patients with DDX41 mutated myelodysplastic syndrome and acute myeloid leukemia Correspondence Published on 2022-08-202022-10-05 Journal: Bone marrow transplantation [Category] 변종, [키워드] Allogeneic DDX41 leukemia mutated Patient syndrome [DOI] 10.1038/s41409-022-01776-6 [Article Type] Correspondence
Clinical features and severe acute respiratory syndrome-coronavirus-2 structural protein-based serology of Mexican children and adolescents with coronavirus disease 20192019년 코로나바이러스 질환이 있는 멕시코 어린이 및 청소년의 임상 특징 및 중증 급성 호흡기 증후군-코로나바이러스-2 구조 단백질 기반 혈청학Article Published on 2022-08-152022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] acute respiratory syndrome analyzed Antibody Response Asymptomatic cause children clinical clinical feature Comorbidities Comorbidity coronavirus disease COVID-19 disease E protein exhibited feature heterogeneous population highest Immunosuppression Infection leukemia levels of antibodies lowest majority Mild Mild-to-moderate number of symptoms obesity Outpatient peptide prevalence of COVID-19 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike serological response serology structural proteins the antibody response treated with COVID-19 [DOI] 10.1371/journal.pone.0273097 PMC 바로가기 [Article Type] Article
A fatal SARS-coronavirus-2 induced bone marrow aplasia complicated with invasive fungal infection and severe neutropenic enterocolitis침습성 진균 감염 및 중증 호중구감소성 장염을 동반한 치명적인 SARS-코로나바이러스-2 유도 골수 무형성증Case Reports Published on 2022-08-092022-09-12 Journal: BMC Infectious Diseases [Category] SARS, 진단, [키워드] age Anemia Aplastic anemia Atypical bone Bone marrow Bone marrow-induced aplasia cause children clinical manifestation complications condition consequence coronavirus disease COVID-19 Critical cross-reactivity demonstrated develop diagnosed diagnostic investigation died Disseminated intravascular coagulopathy Fever Fungal infection healthy HIV Inconclusive infected with SARS-CoV-2 invasive lack leukemia mimicking Pancytopenia Patient Prognosis reactive recognize repeated risk SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 infection. Symptom Symptoms vaccination [DOI] 10.1186/s12879-022-07599-6 PMC 바로가기 [Article Type] Case Reports
Evaluation of serological response to anti-SARS-CoV-2 mRNA vaccination in hematological patients혈액학적 환자에서 anti-SARS-CoV-2 mRNA 백신접종에 대한 혈청학적 반응 평가Article Published on 2022-08-082022-09-12 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] Administered anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-SARS-CoV-2 vaccination Anti-spike anti-Spike IgG anti-spike IgG level antibody Antibody titer association Cell Cohort cohort of patient Concentration control arm control group Cutoff demographic variable difference drug Effect evaluated greater health worker healthy healthy subjects hematological Hematological malignancies Hematological malignancy heterogeneous highest identify IgG IgG titer immune system immunoassay Immunocompromised patients Immunosuppression implication inhibitor Italy leukemia Microparticle molecular mRNA mRNA vaccination mRNA vaccine onco-hematology. parameter pathology Patient patients performed Predictive reached reduced reported SARS-CoV-2 SARS-CoV-2 antibody second dose seroconversion rate serological response shown significantly lower spike IgG statistical significance steroid stratified Surveillance the mean the patient Therapies therapy treated tyrosine underlying disease vaccination Vaccine was reduced [DOI] 10.3389/fimmu.2022.892331 PMC 바로가기 [Article Type] Article
Patients with CLL have a lower risk of death from COVID-19 in the Omicron eraCLL 환자는 오미크론 시대에 COVID-19로 인한 사망 위험이 더 낮습니다Article Published on 2022-08-042022-09-11 Journal: Blood [Category] SARS, 변종, [키워드] 30-Day mortality acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission age antiviral therapy chronic lymphocytic leukemia CLL Cohort cohort of patient Comorbidity Contact coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death declined described disease course dominance General population high mortality hospital Hospitalization hospitalizations Immunocompromised Immunocompromised patient Immunocompromised patients intensive care leukemia lower risk Lymphocytic leukemia omicron Omicron variant outcome Patient population-based cohort positive Previous studies previous study remained reported SARS-CoV-2 SARS-CoV-2 test severe acute respiratory syndrome Coronavirus shown significantly tested variant [DOI] 10.1182/blood.2022016147 PMC 바로가기 [Article Type] Article
COVID-19 mRNA Vaccine in Patients With Lymphoid Malignancy or Anti-CD20 Antibody Therapy: A Systematic Review and Meta-Analysis림프성 악성종양 환자 또는 항-CD20 항체 치료 환자의 코로나19 mRNA 백신: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-08-012022-09-11 Journal: Clinical lymphoma, myeloma & leukemia [Category] 치료제, [키워드] anti-CD20 antibody articles attenuate B-cell B-cell target therapy cellular response Cellular responses chronic lymphocytic leukemia CLL COVID-19 COVID-19 mRNA vaccine COVID-19 mRNA vaccines Effectiveness exhibited humoral Humoral and cellular responses Humoral response independent independent of individual leukemia Long-term follow-up Lymphocytic leukemia lymphoid lymphoma malignancies malignancy material Meta-analysis mRNA mRNA vaccine mRNA vaccines Myeloma Patient PROTECT registration number response to vaccination retrieved review risk risk ratio Seropositivity seropositivity. significantly subtype systematic review T cell T cell responses therapy These data vaccination Vaccine were used within 6 months [DOI] 10.1016/j.clml.2022.03.012 PMC 바로가기 [Article Type] Meta-Analysis
Definition of factors associated with negative antibody response after COVID-19 vaccination in patients with hematological diseases혈액 질환 환자에서 코로나19 백신 접종 후 항체 음성 반응과 관련된 요인 정의Article Published on 2022-08-012022-09-12 Journal: Annals of Hematology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] active treatment addition age Analysis antibody Antibody Response AstraZeneca BNT162b2 BTK inhibitor CML Combination Concentration correlated COVID-19 COVID-19 vaccination Definition demonstrated disease Efficacy Factor had no hematological Hematological diseases/disorders high mortality knowledge leukemia lymphoid median age Moderna mRNA-1273 naïve negative antibody response neoplasm Neoplasms not correlated other disease other diseases Patient patient cohort positive positive response reduced response to vaccination ruxolitinib SARS-CoV-2 seroconversion. significantly single-center study Spike protein Surveillance the SARS-CoV-2 therapy treated Treatment vaccination was performed were measured women [DOI] 10.1007/s00277-022-04866-z PMC 바로가기 [Article Type] Article
357 Skin cancer treatment delays during the COVID-19 pandemicConference abstract Published on 2022-08-012022-10-30 Journal: The Journal of investigative dermatology [Category] Coronavirus, 치료법, [키워드] adverse outcomes age analyzed average Bladder cancer Brain Breast cancer calculated Cancer cancer treatment cancer type Care Colon cancer Colorectal cancer coronavirus COVID-19 pandemic Frequency had more Health IBM information interview investigated leukemia likelihood lung cancer Melanoma Metastasis Mortality multivariate observation Odds ratio P-value Pancreatic cancer pandemic Patient presenting provide respondent significantly more skin cancer SPSS statistical statistically significant study cohort survey Treatment [DOI] 10.1016/j.jid.2022.05.366 [Article Type] Conference abstract
Subcutaneous immunoglobulins in chronic lymphocytic leukemia with secondary antibody deficiency. A monocentric experience during Covid-19 pandemics2차 항체 결핍을 동반한 만성 림프구성 백혈병에서 피하 면역글로불린. Covid-19 전염병 동안의 단일 중심적 경험Article Published on 2022-08-012022-09-12 Journal: Hematological oncology [Category] MERS, 진단, [키워드] administration age antibody appear baseline CD19 CD4/CD8 chronic lymphocytic leukemia CLL Comorbidities COVID 19 deficiency dosage dose Efficacy and safety eligibility event expenditures FIVE Frequency hypogammaglobinemia IgG IgG levels immune immune dysfunction Immunoglobulin immunoglobulin replacement therapy immunoglobulins increase infections initiated interstitial pneumonia leukemia lymphocyte Pandemics Patient Prophylaxis Quality of life receiving reduced risk of infections Safe secondary secondary antibody Subcutaneous subcutaneous immunoglobulins. subset therapy treated Treatment were recorded [DOI] 10.1002/hon.2966 PMC 바로가기 [Article Type] Article
Highly polymerized proanthocyanidins (PAC) components from blueberry leaf and stem significantly inhibit SARS-CoV-2 infection via inhibition of ACE2 and viral 3CLpro enzymes블루베리 잎과 줄기의 PAC(고중합 프로안토시아니딘) 성분은 ACE2 및 바이러스 3CLpro 효소의 억제를 통해 SARS-CoV-2 감염을 크게 억제합니다.Article Published on 2022-07-302022-09-11 Journal: Biochemical and Biophysical Research Communication [Category] COVID19(2023년), SARS, 치료제, [키워드] 3CLpro ACE2 angiotensin Angiotensin II Angiotensin II converting Enzyme antiviral activity Antiviral effect Blueberry component COVID-19 cysteine cysteine protease develop effective enzyme examined extension fraction HCV hepatitis C hepatitis C virus highest HTLV-1 Infection inhibit SARS-CoV-2 inhibited inhibitory effect Inhibitory effects leukemia neutralization neutralization test no effect polymerization polymerized proanthocyanidin Proanthocyanidins pseudotyped SARS-CoV-2 reported SARS-CoV-2 SARS-COV-2 infection significantly Treatment Vaccinium Viral chymotrypsin-like cysteine protease (3CLpro). virus worldwide pandemic [DOI] 10.1016/j.bbrc.2022.04.072 PMC 바로가기 [Article Type] Article