Cytosine base editing inhibits hepatitis B virus replication and reduces HBsAg expression in vitro and in vivoOriginal Article Published on 2023-12-272024-09-05 Journal: Molecular Therapy. Nucleic Acids [Category] update2024, [키워드] base editing cccDNA gene editing HBsAg HBV Lipid nanoparticles MT: RNA/DNA Editing Therapeutics [DOI] 10.1016/j.omtn.2023.102112 PMC 바로가기 [Article Type] Original Article
pH-dependent structural transitions in cationic ionizable lipid mesophases are critical for lipid nanoparticle functionBiological Sciences Pharmacology Published on 2023-12-062024-09-05 Journal: Proceedings of the National Academy of Sciences of [Category] update2024, [키워드] Ionizable lipid Lipid nanoparticles lyotropic mesophases mRNA delivery SAXS [DOI] 10.1073/pnas.2310491120 PMC 바로가기 [Article Type] Biological Sciences Pharmacology
mRNA vaccine trafficking and resulting protein expression after intramuscular administrationOriginal Article Published on 2023-11-242024-09-05 Journal: Molecular Therapy. Nucleic Acids [Category] update2024, [키워드] delivery intramuscular Lipid nanoparticles mRNA MT: Delivery Strategies Trafficking Vaccine [DOI] 10.1016/j.omtn.2023.102083 PMC 바로가기 [Article Type] Original Article
Delivery of Plasmid DNA by Ionizable Lipid Nanoparticles to Induce CAR Expression in T CellsOriginal Research Published on 2023-10-182024-09-05 Journal: International journal of nanomedicine [Category] update2024, [키워드] Cancer immunotherapy CAR T cells cell engineering Lipid nanoparticles pDNA delivery [DOI] 10.2147/IJN.S424723 PMC 바로가기 [Article Type] Original Research
mRNA-based vaccines and therapeutics: an in-depth survey of current and upcoming clinical applicationsarticle Published on 2023-10-072024-09-02 Journal: Journal of Biomedical Science [Category] 대상포진, [키워드] Administration routes Lipid nanoparticles mRNA therapeutics mRNA vaccine Targeting mRNA delivery system [DOI] 10.1186/s12929-023-00977-5 PMC 바로가기 [Article Type] article
Brain-targeted liposomes loaded with monoclonal antibodies reduce alpha-synuclein aggregation and improve behavioral symptoms in Parkinson’s diseaseArticle Published on 2023-09-272024-09-05 Journal: Advanced Materials (Deerfield Beach, Fla.) [Category] update2024, [키워드] brain targeting central nervous system. Lipid nanoparticles Neuroinflammation Parkinson’s disease [DOI] 10.1002/adma.202304654 PMC 바로가기 [Article Type] Article
STING agonist-derived LNP-mRNA vaccine enhances protective immunity against SARS-CoV-2Article Published on 2023-09-202024-09-05 Journal: Nano Letters [Category] update2024, [키워드] Lipid nanoparticles mRNA SARS-CoV-2 Spike protein STING Vaccine [DOI] 10.1021/acs.nanolett.2c04883 PMC 바로가기 [Article Type] Article
Delivery and Expression of mRNA in the Secondary Lymphoid Organs Drive Immune Responses to Lipid Nanoparticle-mRNA Vaccines after Intramuscular Injectionarticle Published on 2023-07-262024-09-05 Journal: Molecular Pharmaceutics [Category] update2024, [키워드] COVID19 Delivery strategy Lipid nanoparticles mRNA nonviral delivery Vaccine [DOI] 10.1021/acs.molpharmaceut.2c01024 PMC 바로가기 [Article Type] article
Rise of the RNA machines – self-amplification in mRNA vaccine designReview Published on 2023-06-142024-09-05 Journal: Trends in Biotechnology [Category] update2024, [키워드] Lipid nanoparticles mRNA Platform technology replicon self-amplifying RNA Vaccines [DOI] 10.1016/j.tibtech.2023.05.007 PMC 바로가기 [Article Type] Review
Nanomaterials in tumor immunotherapy: new strategies and challengesarticle Published on 2023-06-132024-09-05 Journal: Molecular Cancer [Category] update2024, [키워드] Hydrogel nanoparticles Lipid nanoparticles liposomes Nanoemulsions nanomaterials Poly lactic-co-glycolic acid tumor immunotherapy [DOI] 10.1186/s12943-023-01797-9 PMC 바로가기 [Article Type] article