The Association of Low Molecular Weight Heparin Use and In-hospital Mortality Among Patients Hospitalized with COVID-19Observational Study Published on 2022-02-012022-10-05 Journal: Cardiovascular Drugs and Therapy [Category] 임상, [키워드] 95% CI adjusted adjusted odds ratio age Analysis association benefit CHD conducted Coronary heart disease COVID-19 Critically ill D-dimer demonstrated determine diabetes Elderly patient enrolled had more heparin hospital hospitalized COVID-19 patients hypertension IL-6 in-hospital mortality in-hospital mortality rate Inflammatory cytokine IQR limit LMWH LMWH. low molecular weight median age men Mortality mortality risk Older parameter Patient patients with COVID-19 Primary outcome Retrospective study severe COVID-19 severely ill patients survival treated weight with COVID-19 Wuhan, China [DOI] 10.1007/s10557-020-07133-3 PMC 바로가기 [Article Type] Observational Study
Emerging Clinical Features of COVID-19 Related Pancreatitis: Case Reports and Review of the LiteratureMedicine Published on 2022-01-182022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Acute Administered Angiotensin-converting enzyme Antibiotics Antifungal treatment Asymptomatic Atlanta Blood cause clinical Clinical features collected COVID-19 criteria CT-scan demographics diagnosed with COVID-19 discharged evaluate hospital Hospital admission include inhibitors Laboratory less life-threatening literature low molecular weight Other oxygen Pain Patient report respiratory pathogen Result review routine test SARS-CoV-2 severe pancreatitis Symptoms the patient therapy Two patient vital parameter were excluded with COVID-19 [DOI] 10.3389/fmed.2021.779118 PMC 바로가기 [Article Type] Medicine
Low in-hospital mortality rate in patients with COVID-19 receiving thromboprophylaxis: data from the multicentre observational START-COVID Register혈전 예방을 받는 COVID-19 환자의 낮은 병원 내 사망률: 다기관 관찰 START-COVID Register의 데이터Observational Study Published on 2022-01-012022-09-12 Journal: Internal and Emergency Medicine [Category] MERS, 임상, 진단, [키워드] Admission affected Antithrombotic Atrial fibrillation bleeding Cancer cause characteristic Cohort Comorbidities conducted COVID-19 COVID-19 disease COVID-19 infection COVID-19 patient Deep vein Deep vein thrombosis dosage drug DVT enoxaparin fondaparinux heparin high mortality rate Hospital stay Hospitalized hospitalized patients hypertension in-hospital mortality rate interstitial pneumonia Italian low molecular weight low molecular weight heparin major bleeding majority Mortality mortality rate mortality rates multicentre multivariable multivariable analysis Neurological disease observational study outcome pathology Patient patients hospitalized patients older patients with COVID-19 Pulmonary embolism receive receiving reduction retrospective severe interstitial pneumonia significantly survival thromboembolic thromboembolic disease Thromboembolism Thromboprophylaxis thrombosis thrombotic thrombotic event Thrombotic events treated Treatment Venous Thromboembolism [DOI] 10.1007/s11739-021-02891-w PMC 바로가기 [Article Type] Observational Study
Sight-threatening intraocular infection in patients with COVID-19 in India인도의 COVID-19 환자에서 시력을 위협하는 안내 감염Article Published on 2021-12-012022-09-12 Journal: Indian journal of ophthalmology [Category] SARS, 진단, [키워드] Admission age analyzed Antibiotics antiviral drug biopsy caused Comorbidities COVID-19 COVID-19 patient COVID-19-related complication Culture discharge eight endogenous endophthalmitis Epidemiology eye eyes feature fungi hospital Hospitalization Immunosuppressive agents India Infection inhibitor intensive care unit interleukin-6 Intraocular intraocular infection. laboratory-confirmed low molecular weight majority male management microbiologically Microscopy nine ocular ophthalmic outcomes Patient patients patients died patients with COVID-19 PCR positive presenting progressed south India Standard of care supplemental oxygen Symptoms systemic corticosteroid the median Tocilizumab Treatment vitreous [DOI] 10.4103/ijo.IJO_1474_21 PMC 바로가기 [Article Type] Article
TEG ® , Microclot and Platelet Mapping for Guiding Early Management of Severe COVID-19 CoagulopathyReview Published on 2021-11-182022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Activation addition Anticoagulant approach blood clotting caused circulating circulation clinical trials Coagulopathy consumptive coagulopathy COVID-19 COVID-19 patient disease severity dysfunction Efficacy endothelial function Endothelium Factor fibrinolysis Guiding highlight Immune cell Inflammatory Interaction intrinsic low molecular weight maintain management mapping outcome pathway physiological state Platelet platelet activation Platelets Prophylactic receptor reduced required severe COVID-19 severe COVID-19 disease therapeutic Trial von Willebrand factor vWF [DOI] 10.3390/jcm10225381 PMC 바로가기 [Article Type] Review
The Effect of Allicin on the Proteome of SARS-CoV-2 Infected Calu-3 CellsMicrobiology Published on 2021-10-282022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] Allicin Allium Antiviral ARHGAP17 Bacteria Calu-3 Calu-3 cell calu-3 cells caused cell cultures changes in CLTCL1 compounds decrease derivative dose Effect effector effectors exposure expression fungi Future greater GSH Host human cell IFI16 Ifi44 IFN signaling pathway immunomodulatory activity interferon-stimulated gene investigated ISG ISG15 low molecular weight metabolism Modification OAS ORF3 OSBPL2 pathway plant produced Protein proteome proteomics Quantitative reduced Research SARS-CoV-2 SARS-COV-2 infection stability tight junction tissue damage Tolerance Toxicity Transcription translation Treatment uninfected cells Vero E6 VERO E6 cells Vesicular Transport Viral particles Viral protein Viral RNA was used [DOI] 10.3389/fmicb.2021.746795 PMC 바로가기 [Article Type] Microbiology
Treatment for COVID-19—a cohort study from Northern ItalyCovid-19에 대한 치료-이탈리아 북부의 코호트 연구Observational Study Published on 2021-10-252022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, 치료법, 치료제, [키워드] Antiviral Azithromycin clinical evaluation cohort study Combination Corticosteroid COVID-19 patient COVID-19 therapeutics Epidemiology heparin High dose Italy low molecular weight low molecular weight heparin lower mortality multicentre multivariable retrospective cohort study Support survival Tocilizumab Treatment viral infection [DOI] 10.1038/s41598-021-00243-4 PMC 바로가기 [Article Type] Observational Study
PICO Questions and DELPHI Methodology for the Management of Venous Thromboembolism Associated with COVID-19Article Published on 2021-10-222022-10-28 Journal: Viruses [Category] COVID-19, MERS, [키워드] Admission Algorithm Anticoagulant treatment anticoagulation Combination Consensus coronavirus coronavirus disease COVID-19 COVID-19 patient Deep vein thrombosis determine diagnostic discharge disease higher risk hospital hospitalized patient Inflammatory diseases LMWH low molecular weight management methodology oral anticoagulant Patient patients hospitalized patients with COVID-19 pharmacological PICO provide Pulmonary embolism question receiving recommendation Standard dose suggested therapeutic Thromboprophylaxis thrombosis venous thromboembolic venous thromboembolic disease VTE with COVID-19 [DOI] 10.3390/v13112128 PMC 바로가기 [Article Type] Article
Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial치료 헤파린 대 예방 헤파린이 병원에 입원한 중등도의 코로나19 환자에서 사망, 기계적 환기 또는 중환자실 입원에 대한 효과: RAPID 무작위 임상 시험Randomized Controlled Trial Published on 2021-10-142022-09-11 Journal: The BMJ [Category] MERS, SARS, 바이오마커, 임상, 진단, [키워드] 95% confidence interval adaptive Admission age assigned bleeding body mass body mass index Brazil Canada clinical trial Composite D-dimer level death dose evaluate the effect heparin hospital hospital discharge hospital ward Hospital wards ill patient intensive care intensive care unit Invasive mechanical ventilation Ireland low molecular weight Major major bleeding mechanical ventilation men Non-invasive non-invasive mechanical ventilation occurred Odds ratio open open label outcome participant Patient Primary outcome Prophylactic prophylactic dose randomised Randomly recruited reduction in risk Safety Saudi Arabia secondary outcome Secondary outcomes significantly the mean therapeutic therapeutic dose Thromboembolism Trial two patients unfractionated heparin United Arab Emirates Venous Thromboembolism [DOI] 10.1136/bmj.n2400 PMC 바로가기 [Article Type] Randomized Controlled Trial
COVID-19 Infection Clinical Profile, Management, Outcome, and Antibody Response in Kidney Transplant Recipients: A Single Centre ExperienceResearch Article Published on 2021-10-032022-10-29 Journal: International Journal of Nephrology [Category] COVID-19, [키워드] age AKI analyzed Antibiotics Antibody Response Blood Blood Group blood urea clinical CNI Confirmed COVID-19 infection convalescent plasma COVID-19 Culture dialysis doxycycline experience Factor hospitalized patients ICU care IgG antibody inhibitor interleukin-6 IQR Ivermectin Kidney injury kidney transplant recipient Laboratory low molecular weight management Material and Method median value Mortality mortality rate mounted nonsurvivor nonsurvivors not significantly different outcomes overall mortality Patient PCR pharmacological management polymerase chain positive presenting profile recovered Remdesivir reported response Result retrospective Risk factors SARS-CoV-2 serum albumin severity Significant statistically significant steroid Support survivor Survivors therapy Tocilizumab Transplant Treatment ventilated patient Ventilation was collected with COVID-19 [DOI] 10.1155/2021/3129411 PMC 바로가기 [Article Type] Research Article