Advances in MERS-CoV Vaccines and Therapeutics Based on the Receptor-Binding DomainReview Published on 2019-01-142022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] advance antibodies coronavirus Critical domain Efficacy ENCODE feature IMPROVE in viral Infection Infectious virus MERS MERS-CoV MERS-CoV genome Middle East Neutralizing Pathogenesis Protein RBD Receptor-binding domain reported S-protein Spike protein structural proteins syndrome the S protein therapeutic Therapeutics Vaccine Vaccines [DOI] 10.3390/v11010060 PMC 바로가기 [Article Type] Review
Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirusResearch Published on 2018-05-242022-10-29 Journal: Journal of Biomedical Science [Category] Coronavirus, [키워드] addition assembly C-terminal domain coexpressed Culture dependent on expression functional GFP help Heterologous HUH7 cells indicated membrane MERS MERS-CoV MERS-CoV genome Microscopy Middle East mRNA N-terminal domain nucleocapsid protein nucleotide Particle positive-sense Protein respiratory syndrome coronavirus Result RNA RNA fragment RNA genome RNA packaging signal RNA structure SARS-CoV sequence single-stranded structural protein structural proteins the viral nucleocapsid viral genome virus virus infection virus particle VLP VLPs was determined [DOI] 10.1186/s12929-018-0449-x PMC 바로가기 [Article Type] Research
Diversity of Middle East respiratory syndrome coronaviruses in 109 dromedary camels based on full-genome sequencing, Abu Dhabi, United Arab EmiratesOriginal Article Published on 2017-11-082022-10-31 Journal: Emerging Microbes & Infections [Category] Coronavirus, [키워드] Abu Arabian Peninsula breakpoint circulating clade coronavirus described Diversity Dromedary Emirate expand gene sequence Genome Human human infections Hypothesis Incubation period junction Lineage lineages MERS MERS-CoV MERS-CoV genome MERS-CoV infection Middle East Middle East respiratory syndrome Coronavirus ORF1b outbreak positive Recombination recombination event Region reported respiratory syndrome coronavirus screened sequence sequenced Sequencing spike subset supported syndrome United Arab Emirate United Arab Emirates virus [DOI] 10.1038/emi.2017.89 PMC 바로가기 [Article Type] Original Article
Molecular Evolution of MERS Coronavirus: Dromedaries as a Recent Intermediate Host or Long-Time Animal Reservoir?Article Published on 2017-10-162022-10-29 Journal: International Journal of Molecular Sciences [Category] Coronavirus, Fulltext, 조류인플루엔자, [키워드] amino acid substitutions Analysis analyzed animal clade Codons dromedaries Dromedary Evolution FIVE GenBank highest Host implication Infection intermediate Lineage lineages MERS MERS coronavirus MERS-CoV MERS-CoV genome molecular origin recent Recombination recombination event reservoir residue S protein Saudi Arabia selected sequence Spike protein strain Strains while [DOI] 10.3390/ijms18102138 PMC 바로가기 [Article Type] Article
Laboratory Investigation and Phylogenetic Analysis of an Imported Middle East Respiratory Syndrome Coronavirus Case in GreeceResearch Article Published on 2015-04-282022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] addition amino acid substitution Analysis changes in coding sequence collected conducted Diagnosis disease Efficiency Genes Greece help highlight identify implementation implication Inconclusive Infection infection control initial investigation Jeddah Laboratory laboratory investigation Lower respiratory tract management MERS-CoV MERS-CoV genome MERS-CoV infection MERS-CoV RNA Middle East molecular Mutation nucleocapsid oropharyngeal swab patient hospitalization performed positive positive swab sample Rapid real-time RT-PCR Receptor binding Receptor binding domain Region respiratory respiratory syndrome coronavirus Result RNA-dependent RNA polymerase rRT-PCR RT-PCR Saudi Arabia Sequencing serological test specimen spike gene strain Swab swab sample tested Transmission unique virus virus transmission [DOI] 10.1371/journal.pone.0125809 PMC 바로가기 [Article Type] Research Article