Lack of evidence for post-vaccine onset of autoimmune/lymphoproliferative disorders, during a nine-month follow-up in multiply vaccinated Italian military personnelarticle Published on 2017-08-312024-09-01 Journal: Clinical Immunology [Category] 파상풍, [키워드] Apoptotic self-epitopes Autoimmunity lymphoproliferation microarray analysis Military personnel Vaccinations [Article Type] article
Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory virusesResearch Article Published on 2017-06-022022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] 24 hours antiviral genes approach can be used caused Cell cellular response changes changes in coronavirus Defense dependent on disease Effect elicited epithelial cell expression Gene Expression Host host gene expression host response hours post-infection in vitro study in vivo Infection influenza A virus lung epithelial cell Lung epithelial cells mechanism mice microarray analysis Mild moderate mounted murine overlapping parameters Pathogenesis peaked respiratory tract respiratory viral infection respiratory viral infections respiratory virus response rhinovirus severity signature tissue remodeling transcription factor transcriptional Treatment type I interferon unique virus virus infection viruses [DOI] 10.1371/journal.pone.0178408 PMC 바로가기 [Article Type] Research Article
MicroRNA profile analysis in the liver fibrotic tissues of chronic hepatitis B patientsArticle Published on 2017-02-012023-06-19 Journal: Journal of digestive diseases [Category] B형 간염, [키워드] Chronic Hepatitis B fibrosis Liver cirrhosis microarray analysis MicroRNAs [DOI] 10.1111/1751-2980.12452
Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescencep53 및 Rb의 조절은 대체 NF-κB 경로를 EZH2 발현 및 세포 노화에 연결합니다Research Article Published on 2014-09-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activated Activation alternative NF-κB pathway Analysis ANAPC1 c-Rel cancer cell Cancer cells CD40 CD40 ligand CD40L CDK4 CDK6 Cell cell cycle cell senescence cellular senescence ChIP chromatin immunoprecipitation chronic chronic lymphocytic leukemia classical complexes Crosstalk de-repression defined Degradation DEK dependent on Effect effector effectors expression EZH2 fibroblasts Hematological malignancies Hematological malignancy IKK IKKα induce inhibit investigated IκB IκBα knockdown leads Loss Lymphocytic leukemia mechanism microarray analysis microenvironment NEMO NF-κB NF-κB inducing kinase NF-κB pathway NF-κB2 NIK or canonical oxygen p100 p21WAF1 p52 p53 pathway patients phenotype Phosphorylation polycomb protein promote protein stability provide PSMA5 quantitative PCR RacGAP1 reactive oxygen species reactive oxygen specy regulate Regulation regulatory subunit RELA RelB repression retinoblastoma retinoblastoma protein ROS SASP senescence senescent siRNA solid tumors stability stimulated subset subunit subunits suppress suppression target gene Target genes the cell Tumor tumor suppressor tumorigenesis tumors tumour suppressor turn western blot Western blot analyses Western blot analysis wild type [DOI] 10.1371/journal.pgen.1004642 PMC 바로가기 [Article Type] Research Article
The Transcription Factor BcLTF1 Regulates Virulence and Light Responses in the Necrotrophic Plant Pathogen Botrytis cinerea전사 인자 BcLTF1은 괴사성 식물 병원체 Botrytis cinerea에서 독성과 빛 반응을 조절합니다Research Article Published on 2014-01-092022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence accumulation addition Affect alternative oxidase alternative respiration enzymes antioxidants AOX apothecia applied approach arising Aspergillus nidulan Aspergillus nidulans Author BcLTF1 bctlf1 Botrytis cinerea caused characterized circadian rhythm conditions conidia continuous light Deletion dependent on detoxification detrimental effect detrimental effects dicotyledonous plant differentiation dispersal ecological ecological niche equilibrium Evidence exogenously exposure to expression expression level expression levels expression of gene Factor fertilization filamentous fungi fruiting bodies function fungal fungal pathogen fungi fungus GATA transcription factor Gene gene encoding Genes gray mold disease gray mold diseases growth rate growth rates homoeostasis homologue Host host infection hypersensitivity illumination impair Increased increased expression induce Infection LIGHT macroconidia macromolecule macromolecules majority metabolism Microarray analyses microarray analysis microconidia mitochondrial mitochondrial dysfunction modulated mutant mutants necrotrophic pathogen necrotrophic pathogen Botrytis cinerea Neurospora crassa NsdD Organisms Orientation over-expression overexpression oxidative stress oxygen Pathogens photomorphogenesis photoreceptor phototropism pigments plant plants predicted propagule propagules PROTECT random mutagenesis reactive oxygen species reactive oxygen specy Regulation reproductive required respiration enzymes respond response restoration ROS scavenging sclerotia Secondary metabolism sexual reproduction singlet oxygen spores Structure structures SUB-1 survival TF 1 transcription factor transcriptional level virulence [DOI] 10.1371/journal.pgen.1004040 PMC 바로가기 [Article Type] Research Article
Transcriptomic Profiling in Childhood H1N1/09 Influenza Reveals Reduced Expression of Protein Synthesis GenesArticle Published on 2013-11-152023-06-09 Journal: The Journal of Infectious Diseases [Category] Fulltext, 신종인플루엔자, [키워드] eIF-2 Kinase Gene expression profiling Influenza microarray analysis pediatric Peptide Chain Initiation respiratory tract infection RSV [DOI] 10.1093/infdis/jit348 PMC 바로가기
Improved microarray gene expression profiling of virus-infected cells after removal of viral RNAMethodology Article Published on 2008-05-142022-10-28 Journal: BMC Genomics [Category] Coronavirus, MERS, [키워드] Accuracy acquisition alteration analyses conditions coronavirus detect different False-positive Gene Expression Gene expression profiling host cell IMPROVE Improved infected cell Infection interfere investigated mean Microarray microarray analysis Microarrays reduced reliability Result RNA RNAs sensitivity significantly tested total RNA Viral RNA virus-infected cell vRNA [DOI] 10.1186/1471-2164-9-221 PMC 바로가기 [Article Type] Methodology Article
Oligonucleotide microchip for subtyping of influenza A virusOriginal Article Published on 2007-10-222023-05-31 Journal: Influenza and Other Respiratory Viruses [Category] 조류인플루엔자, [키워드] H5N1 subtype hemagglutinin influenza A virus microarray analysis neuraminidase [DOI] 10.1111/j.1750-2659.2007.00018.x PMC 바로가기 [Article Type] Original Article