Current trends in COVID-19 diagnosis and its new variants in physiological fluids: Surface antigens, antibodies, nucleic acids, and RNA sequencingReview article Published on 2022-12-012022-10-05 Journal: TrAC Trends in Analytical Chemistry [Category] 바이오마커, 변종, 진단, 치료기술, [키워드] addressed antibodies antibody Antigen antigens Beta Biomarker biosensors Blood body fluid circulation clustered regularly interspaced short palindromic repeats COVID-19 COVID-19 diagnosis COVID-19 virus diagnosis CRISPR Critical current Delta Detection sensitivity diagnostic early stage ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Gamma Infection isothermal amplification lateral flow immunoassay LFIA limit Loop-mediated isothermal amplification microarray analysis Microarray assays Mutation nucleic acid nucleic acids omicron outbreak overcome palindromic repeat physiological provide Rapid reduce reverse transcriptase-polymerase chain reaction reverse transcription RNA sequencing RT-LAMP RT-PCR Saliva SARS-CoV-2 Semen specificity Spread surface Urine variant variants virus viruses [DOI] 10.1016/j.trac.2022.116750 [Article Type] Review article
Plasmonic Fluor-Enhanced Antigen Arrays for High-Throughput, Serological Studies of SARS-CoV-2SARS-CoV-2의 높은 처리량, 혈청학적 연구를 위한 플라즈몬 형광 강화 항원 어레이Article Published on 2022-08-122022-09-11 Journal: ACS Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 96-well plate acute infection Antigen antigenic antigenic drift Bioscience Characteristics clinical sensitivity coordination COVID-19 pandemic Critical current diagnostics eight evaluate fluorescent highlight IgA IgG IgM Laboratory limitation limitations management microarray analysis microplate reader multiplex Outbreaks Patient Patient management plasmonics public health ranged reagents reminder response resulting Sample SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 detection SARS-CoV-2 positive patients Screening sensitivities sensitivity serological assays serological response serological studies SEROLOGICAL STUDY Serological testing serology several limitations specificity subset symptomatic used to evaluate Volume was performed were used [DOI] 10.1021/acsinfecdis.2c00086 PMC 바로가기 [Article Type] Article
Using Cy5-dUTP labelling of RPA-amplicons with downstream microarray analysis for the detection of antibiotic resistance genesArticle Published on 2021-10-112022-10-04 Journal: Scientific Reports [Category] 진단, [키워드] amplicons amplification antibiotic resistance gene Biological techniques Cell detect diagnostics Disadvantages downstream dTTP Escherichia coli flexible Genes Genomic DNA isothermal isothermal amplification method less microarray analysis Molecular biology overcome pathogen performed point of care primer Primers probe provide RPA sensitivity Target genes [DOI] 10.1038/s41598-021-99774-z PMC 바로가기 [Article Type] Article
Inflammation and Antiviral Immune Response Associated With Severe Progression of COVID-19COVID-19의 심각한 진행과 관련된 염증 및 항바이러스 면역 반응Clinical Trial Published on 2021-02-182022-08-13 Journal: Frontiers in Immunology [Category] MERS, 바이오마커, 신종인플루엔자, 유전자 메커니즘, 임상, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 applied coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 severity Disease progression disease severity downregulation Ex vivo Functional enrichment analysis H1N1 H1N1 virus healthy controls hemagglutinin host immune system hypercytokinemia IFNs immune cells immune response immune signature impair impaired function include indicate indicated Infection Inflammation Inflammatory Inflammatory response Influenza influenza A interferons LAG3 microarray analysis mild COVID-19 patient MMP9 mononuclear cell mononuclear cells myeloid cell myeloid cells Neutrophils novel respiratory disease overactivation overactive patients patients with influenza PBMC PBMCs Peripheral blood Peripheral blood mononuclear cells potential mechanism potential mechanisms progression promote proportion Protein regulate Regulation respiratory Respiratory disease respond response SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe and mild COVID-19 patients severe COVID-19 severe SARS severe SARS-CoV-2 severity Signaling SKAP1 spike Spike protein Stimulation suggested T cell T cells T cells TLR6 Transcriptome Type I IFN type I IFNs type I interferon type I interferons unique upregulation whole genome transcriptome with COVID-19 [DOI] 10.3389/fimmu.2021.631226 PMC 바로가기 [Article Type] Clinical Trial
Antibody dynamics to SARS-CoV-2 in asymptomatic COVID-19 infections무증상 COVID-19 감염에서 SARS-CoV-2에 대한 항체 역학Article Published on 2021-02-012022-09-12 Journal: Allergy [Category] MERS, SARS, 진단, [키워드] analyzed antibodies antibody Antibody dynamics Asymptomatic Asymptomatic carrier Asymptomatic COVID-19 asymptomatic individual asymptomatic infections Biomarker Combination condition controls COVID-19 demonstrated Detection sensitivity Diagnosis diagnostic did not produce dynamics of antibody Enrollment epidemiologically healthy individual Humoral immunity IgM and IgG IgM antibody IgM responses immunization strategies implication individual Infection infections knowledge Microarray microarray analysis mild patient N protein Neutralization assay neutralizing antibody nucleic acid pandemic peaked produced profile Protein proteome Pseudotyped virus public health raise recruited SARS-CoV-2 SARS-CoV-2 proteome screened sensitivity serological serological survey Serological testing serum significantly symptoms onset the NAT [DOI] 10.1111/all.14622 PMC 바로가기 [Article Type] Article
Decoding the complexities of human malaria through systems immunologyarticle Published on 2020-01-312024-09-01 Journal: Immunological Reviews [Category] 말라리아, [키워드] Gene expression profiling host response Malaria immunity malaria immunology microarray analysis Plasmodium falciparum Plasmodium vivax Systems biology systems immunology Systems vaccinology transcriptomics [Article Type] article
Microarray analysis reveals the inhibition of intestinal expression of nutrient transporters in piglets infected with porcine epidemic diarrhea virusArticle Published on 2019-12-242022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] administration Amino acid amino acid transporter Analysis biochemical test Biochemistry Blood blood sample collected Concentration control group Culture death diamine oxidase diarrhea dysfunction Effect epidemic diarrhea expression expression of gene fatty fibrosis Glucose growth healthy incidence induce Infection infectious dose infused inhibit insulin intestinal intestinal injury L-type lipid transport microarray analysis Molecular biology mRNA level Neutral PEDV peptide phosphoenolpyruvate plasma profiles Protein Randomly receptor reducing resulting reveal sterile saline TCID tissue transmembrane Transport two groups virus [DOI] 10.1038/s41598-019-56391-1 PMC 바로가기 [Article Type] Article
Development and validation of a new tumor-based gene signature predicting prognosis of HBV/HCV-included resected hepatocellular carcinoma patientsResearch Published on 2019-06-182023-06-03 Journal: Journal of Translational Medicine [Category] B형 간염, Fulltext, [키워드] Hepatocellular carcinoma Liver resection microarray analysis Molecular classification [DOI] 10.1186/s12967-019-1946-8 PMC 바로가기 [Article Type] Research
Microarray analysis of long non-coding RNA expression profiles in monocytic myeloid-derived suppressor cells in Echinococcus granulosus -infected miceResearch Published on 2018-05-302023-05-31 Journal: Parasites & Vectors [Category] Fulltext, 조류인플루엔자, [키워드] Echinococcus granulosus expression profile Long non-coding RNAs microarray analysis myeloid-derived suppressor cells [DOI] 10.1186/s13071-018-2905-6 PMC 바로가기 [Article Type] Research
Innate immune response of bovine mammary epithelial cells to Mycoplasma bovis소 유선 상피 세포의 마이코플라스마 보비스에 대한 선천 면역 반응Article Published on 2018-01-312024-08-21 Journal: Journal of Veterinary Science [Category] 살모넬라증, [키워드] bovine mammary epithelial cells Cytokines Innate immunity microarray analysis Mycoplasma bovis