COVID‐19 and coagulopathyReview Article Published on 2021-08-302023-06-15 Journal: The clinical respiratory journal [Category] MERS, SARS, [키워드] COVID‐19 Endotheliitis heparin Microthrombosis thrombosis [DOI] 10.1111/crj.13438 PMC 바로가기 [Article Type] Review Article
Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality내피 손상의 표지자로서 순환하는 폰 빌레브란트 인자와 고분자량 다량체가 COVID-19 병원 내 사망률을 예측합니다Article Published on 2021-08-012022-09-11 Journal: Angiogenesis [Category] MERS, SARS, 바이오마커, [키워드] Accuracy adjusted Admission age Analysis Antigen best Biomarker BMI C-reactive protein Clinical severity Cohort coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 adult patients COVID-19 outpatient COVID-19 outpatients COVID-19 patient COVID-19 patients Cox proportional hazard model Critical critical patients cut-off D-dimer levels endothelial endothelial activation Endothelial dysfunction endothelial injury Endotheliitis enrolled excess forms hazard hospitalized patient in-hospital mortality intensive care intensive care unit IQR Kaplan-Meier estimator laboratory-confirmed Laboratory-confirmed COVID-19 marker median Microthrombosis Mild molecular weight Mortality MOST Multimers Outpatient Patient patients hospitalized predict Predictive respiratory Respiratory disease ROC Curve scaled significantly higher tested transferred von Willebrand factor vWF were measured [DOI] 10.1007/s10456-020-09762-6 PMC 바로가기 [Article Type] Article
Von Willebrand factor collagen-binding capacity predicts in-hospital mortality in COVID-19 patients: insight from VWF/ADAMTS13 ratio imbalance폰 빌레브란트 인자 콜라겐 결합 능력은 COVID-19 환자의 병원 내 사망률을 예측합니다: VWF/ADAMTS13 비율 불균형으로부터의 통찰력Article Published on 2021-08-012022-09-11 Journal: Angiogenesis [Category] SARS, 바이오마커, [키워드] 48 hour 48 hours 95% CI ADAMTS13 adjusted Admission Analysis AUC balance best Biomarker BMI C-reactive protein collagen Collagen-binding COVID-19 COVID-19 severity Critical cut-off D-dimer levels described enrolled hallmark hazard Hospital mortality hospitalized COVID-19 patient in-hospital mortality IQR Kaplan-Meier estimator median Microthrombosis molecular weight Mortality Multimers Patient Plasma level Plasma levels predict Predictive ROC Curve shown significantly subsequent Trigger von Willebrand factor vWF was increased were measured [DOI] 10.1007/s10456-021-09789-3 PMC 바로가기 [Article Type] Article
Case Report: Co-occurrence of Myocarditis and Thrombotic Microangiopathy Limited to the Heart in a COVID-19 PatientCardiovascular Medicine Published on 2021-07-292022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] Analysis anticoagulation Capillaries Combination COVID-19 death described died Diffuse alveolar damage disease etiology feature female healthy heart inflammatory reaction initial Limited Lungs microangiopathy Microthrombosis myocarditis myocarditis acute and fulminant other organs Patient positive prevalent Prophylactic required risk stratification SARS-CoV-2 Symptoms the patient Thromboinflammation Thromboprophylaxis thrombotic Thrombus [DOI] 10.3389/fcvm.2021.695010 PMC 바로가기 [Article Type] Cardiovascular Medicine
Histological Evidence of Pulmonary Microthrombosis and Vasculitis in Life-Threatening Respiratory Virus DiseasesBrief Reports Published on 2021-02-282022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] acute respiratory distress syndrome acute respiratory syndrome Adenovirus autopsy study coronavirus disease determine Evidence evidence of fatal influenza Influenza life-threatening Microthrombosis Middle East occur patients pulmonary reported respiratory respiratory syncytial virus Respiratory virus infections SARS Coronavirus syndrome thrombosis Vasculitis [DOI] 10.1093/ofid/ofaa640 PMC 바로가기 [Article Type] Brief Reports
The ADAMTS13-von Willebrand factor axis in COVID-19 patientsCOVID-19 환자의 ADAMTS13-von Willebrand 요인 축Article Published on 2021-02-012022-09-11 Journal: Journal of thrombosis and haemostasis : JTH [Category] 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus ADAMTS13 ADAMTS13 Protein Admission Antigen Care characterized cofactor coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients COVID-19 progression cross-sectional cross-sectional study Deceased disease severity elevated ENhance Evidence evidence of hypercoagulable Hypercoagulable state Imbalance increased risk intensity lung Lungs mechanical ventilation mechanism median Microthrombosis microvasculature nasal nasal cannula Oxygenation Patient patients positive airway pressure propeptide ranged respiratory risk severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe coronavirus disease stratified thromboembolic Thromboembolic events thrombosis von Willebrand factor vWF with intensity [DOI] 10.1111/jth.15191 PMC 바로가기 [Article Type] Article
Anatomical and Pathological Observation and Analysis of SARS and COVID-19: Microthrombosis Is the Main Cause of DeathReview Published on 2021-01-202022-10-27 Journal: Biological Procedures Online [Category] COVID-19, [키워드] Activation Affect alveolar anticoagulation ARDS Autopsy Blood cause caused characteristic characterized clinical manifestations Coagulation coronavirus Course COVID-19 COVID-19 patient COVID-19 patients D-dimer DAD damage dead patient death decrease Degradation described diffuse Diffuse alveolar damage disease disorder Disseminated intravascular coagulation distress down-regulation effective endothelial injury epithelial expression fibrinogen host response hyaline membrane formation Hypoxemia include increase in Inflammation intravascular coagulation Invasion mechanism membrane permeability Microcirculation Dysfunction Microthrombosis microthrombus multiple organ failure neutrophil infiltration Occurrence pathological pathological change pathology pathway Pathways patients with COVID-19 physiological Platelet progression reported Research SARS-CoV-2 SARS-CoV-2 cell SARS-COV-2 infection severe COVID-19 severity Spread subsequent syndrome the disease the patient therapy thrombosis Thrombotic complications tissue Treatment turn Vascular [DOI] 10.1186/s12575-021-00142-y PMC 바로가기 [Article Type] Review
Understanding the andromeda strain – The role of cytokine release, coagulopathy and antithrombin III in SARS-CoV2 critical illness안드로메다 균주 이해 - SARS-CoV2 중병에서 사이토카인 방출, 응고병증 및 안티트롬빈 III의 역할Review Published on 2021-01-012022-09-11 Journal: Blood reviews [Category] SARS, 바이오마커, [키워드] Antithrombin antithrombin III autopsy analysis benefit China circulating Coagulation Coagulopathy coronavirus COVID-19 COVID-19 infections Critical Critical illness cytokine release Europe globe hematology heparin Heparin resistance mediator Microthrombosis Mortality Multiple observational studies observational study organizations pandemic Part pathology pathophysiology Patient performed physician potential therapeutic target Prognostic marker Prophylactic prothrombotic reduction reductions reported SARS-CoV SARS-CoV critical illness SARS-CoV2 severe COVID-19 infections Society temper thrombosis thrombotic thrombotic complication Thrombotic complications understanding [DOI] 10.1016/j.blre.2020.100731 PMC 바로가기 [Article Type] Review
Letter in response to: Coagulation markers are independent predictors of increased oxygen requirements and thrombosis in COVID-19에 대한 답장: 응고 마커는 COVID-19의 증가된 산소 요구량 및 혈전증의 독립적인 예측자입니다.Comment Published on 2020-12-012022-09-11 Journal: Journal of thrombosis and haemostasis : JTH [Category] MERS, SARS, 바이오마커, [키워드] Abstract anfibatide caplacizumab COVID COVID 19 COVID-19 endotheliopathy independent predictor marker Microthrombosis microthrombosis. Oxygen requirement thrombosis [DOI] 10.1111/jth.15080 PMC 바로가기 [Article Type] Comment
More than Pneumonia: Distinctive Features of SARS-Cov-2 Infection. From Autopsy Findings to Clinical Implications: A Systematic ReviewReview Published on 2020-10-232022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Acute kidney injury (AKI) acute respiratory distress acute respiratory distress syndrome (ARDS) alveolar ARDS Autopsies Autopsy autopsy study bronchopneumonia Case series clinical clinical feature Comorbidity Complete contributed COVID-19 COVID-19 disease Cytokine storm dataset death died diffuse alveolar damage (DAD) disease endothelial damage Features finding gold standard histopathological features inclusion criteria Infection Inflammatory management Microthrombosis multiple organ failure pathogen patients with COVID-19 Post-mortem producing provided recommendation Research resulting retrospective review subject syndrome systematic review Therapeutic approach Thromboembolism was performed with COVID-19 [DOI] 10.3390/microorganisms8111642 PMC 바로가기 [Article Type] Review