Outcome of COVID19 in Patients With Osteogenesis Imperfecta: A Retrospective Multicenter Study in Saudi ArabiaEndocrinology Published on 2022-01-132022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, [키워드] age bisphosphonate children collagen complications condition contributed Course COVID - 19 COVID-19 COVID-19 in patient COVID-19 severity COVID19 disease evaluate Fracture functional genetic disease Genetic diseases genetic disorder hospital Hospitalization IMPROVE ineligible infected with COVID-19 Infection Jeddah Kyphoscoliosis less male Mild mild illness multicenter study Osteogenesis osteogenesis imperfecta outcome Patient patients Pneumonia prognosis of patient reduce Restrictive lung disease Result resulting retrospective Saudi Arabia skeletal the patient vaccination was performed were recorded with COVID-19 [DOI] 10.3389/fendo.2021.800376 PMC 바로가기 [Article Type] Endocrinology
Neutralizing antibody responses over time in demographically and clinically diverse individuals recovered from SARS-CoV-2 infection in the United States and Peru: A cohort study미국과 페루에서 SARS-CoV-2 감염에서 회복된 인구통계학적 및 임상적으로 다양한 개인에서 시간이 지남에 따라 항체 반응 중화: 코호트 연구Research Article Published on 2021-12-062022-09-12 Journal: PLoS Medicine [Category] 진단, [키워드] 293T/ACE2 cells acute respiratory syndrome coronavirus age age and sex analyses Analysis antibody Antibody Response applied assigned association Asymptomatic Birth Blood body mass body mass index Clinical characteristics clinical manifestations Clinical outcome clinical outcomes clinically Cohort cohort study collected Comorbidities Comorbidity convalescent convalescent individual convalescent individuals coronavirus 2 coronavirus disease Coronavirus disease 2019 correlation COVID-19 death declined demographic and clinical characteristics Demographic variables demographics diabete diabetes disease onset disease severity enrolled Factors help heterogeneity highlighting Hispanic hypertension identify immune defense immune response immune responses Immunity implementation in some include individual Infection limitation Linear regression Male sex medical history mild illness Multiple Multiple linear regression NAb NAb responses NAb titers NAbs nasal samples natural history Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing antibody responses not differ observation participant peaked Protective pulmonary disease Questionnaires researcher respiratory response responses SARS-CoV-2 SARS-CoV-2 antibody response SARS-COV-2 infection SARS-CoV-2 spike protein serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe coronavirus disease Sex smoking Spike protein survivorship the United State therapeutic strategy Therapeutics thought titers to define Treatment Trial registration United States Vaccine Variation variety Viral load virus virus infection were measured white [DOI] 10.1371/journal.pmed.1003868 PMC 바로가기 [Article Type] Research Article
New insights into genetic characteristics between multiple myeloma and COVID-19: An integrative bioinformatics analysis of gene expression omnibus microarray and the cancer genome atlas data다발성 골수종과 COVID-19 사이의 유전적 특성에 대한 새로운 통찰력: 유전자 발현 옴니버스 마이크로어레이와 암 게놈 아틀라스 데이터의 통합 생물정보학 분석Comparative Study Published on 2021-12-012022-09-11 Journal: International journal of laboratory hematology [Category] SARS, 유전자 메커니즘, [키워드] 95% CI association bioinformatics Bioinformatics analysis Cancer Characteristics Cohort Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Cox regression analysis COX6C Cytochrome C cytochrome c oxidase data set DEGs differentially expressed gene Differentially expressed genes domain downregulated expression Factor Features FIVE Functional enrichment analysis Gene Expression Genetic Genome Hematological malignancy identify independent Infection Microarray Mild mild illness Multiple Multiple myeloma New NOD2 nucleotide oligomerization overall survival Patient performed Prognosis prognostic biomarker Prognostic biomarkers protein-protein interaction screened severe COVID-19 subunit survival upregulated with COVID-19 [DOI] 10.1111/ijlh.13717 PMC 바로가기 [Article Type] Comparative Study
A review of acute pancreatitis in the era of COVID-19Review article Published on 2021-12-012022-10-05 Journal: Paediatrics and Child Health [Category] 유전자 메커니즘, [키워드] acute pancreatitis approach association childhood children collected Complication Course COVID-19 Diagnosis disease disease pathogenesis Epidemiology Evidence genetics high risk Hospital admission incidence Intervention invasive management mild illness morbidity and mortality Mortality MOST multiorgan failure occurred paediatric pancreatitis pathophysiology Prognosis progression resulting severe disease significantly suggested [DOI] 10.1016/j.paed.2021.09.001 [Article Type] Review article
Transmission dynamics, clinical characteristics and sero-surveillance in the COVID-19 outbreak in a population dense area of Colombo, Sri Lanka April- May 20202020 년 4 월 ~ 5 월 스리랑카 콜롬보의 인구 밀도가 높은 지역에서 Covid-19 발병에서 전송 역학, 임상 특성 및 혈청 조사Research Article Published on 2021-11-082022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] 95% CI age Asthma Asymptomatic asymptomatic individual attack rate B.1 cardiovascular disease carried Characteristics circulating SARS-CoV-2 variants circulation Clinical characteristics close contact Colombo COVID-19 COVID-19 outbreak D614G mutation D614G variant detectable diabetes disease severity environmental factors epidemiological Factor Host illnesses index case individual infected individual lead Lineage majority Mild mild illness NAbs Neutralizing antibodies neutralizing antibody occurred outbreak positive individual RT-qPCR SARS-CoV-2 SARS-CoV-2 specific antibodies SARS-CoV-2 variants SARS-CoV2 secondary attack rate sequenced seropositive social distancing measures Symptom the SARS-CoV-2 total antibodies total antibody Transmission Transmission dynamics virus viruses [DOI] 10.1371/journal.pone.0257548 PMC 바로가기 [Article Type] Research Article
146. Intact Sense of Taste and Smell During COVID-19 Infection Is Associated with Absence of of SARS-CoV-2 Spike Protein Antibody Responses within 3 Months of Symptomatic IllnessOral Abstracts Published on 2021-11-042022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] age Alpha Anosmia/ageusia antibody Antigen Asian association baseline beta coronavirus black breadth characterized clinical factors clinical phenotypes clinically Cohort collected company Control cough COVID-19 COVID-19 infection COVID-19 symptoms cross-reactivity demographics demonstrated description difference disease disease severity employee enrolled Epitopes female Fever figure group had no health system heterogeneous identify illness immune response Immunity include Intact Josh less Lilly list magnitude mild illness mild infection Month mRNA vaccination participant Patient patient population PCR-confirmed plasma sample platform Post-infection predict Prevent profile Protective Protein questionnaire Re-infection recovered patients reported response responses Result Robert SARS-CoV-1 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 spike protein sense sense of smell significantly Smell spike Spike protein Stephanie survivor symptom onset symptomatic Symptoms Taste tested the antibody response white [DOI] 10.1093/ofid/ofab466.146 PMC 바로가기 [Article Type] Oral Abstracts
390. Can Testing the Environment for SARS-CoV-2 Be a Signal for Staff Infections in Nursing Homes (NHs)?Poster Abstracts Published on 2021-11-042022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] association calculated Can can be used Clustering Cohen’s kappa Concordance conducted Contamination contributed COVID-19 case COVID-19 testing cross effective Environment evaluated home hospital increase in limit of detection Linear regression model mandatory material mild illness Negative predictive value NPV Nursing object Other PCR performed positive positive sample PPV processed proportion Result SARS-CoV-2 signal staff Stryker table tested Testing Total [DOI] 10.1093/ofid/ofab466.591 PMC 바로가기 [Article Type] Poster Abstracts
Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies심각한 코로나바이러스 질병 2019(COVID-19)는 상승된 혈청 면역글로불린(Ig) A 및 항인지질 IgA 항체와 관련이 있습니다Article Published on 2021-11-022022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, [키워드] antibody Antiphospholipid syndrome Antiviral approach Autoimmune diseases autoimmune responses Autoimmunity Clinical data clinical record Cohort collected Complication coronavirus disease correlated COVID-19 determine diagnostic elevated excluded hospital IgA IgA antibody IgA response IgG IgM Immunoglobulin immunoglobulin A independent induce mild illness mucosa Patient patients with COVID-19 retrospective cohort study Sample severe COVID-19 significantly similarity Switzerland syndrome systemic thromboembolisms. thrombotic event Total triggered were measured [DOI] 10.1093/cid/ciaa1496 PMC 바로가기 [Article Type] Article
Interventions to Disrupt Coronavirus Disease Transmission at a University, Wisconsin, USA, August–October 2020Synopsis Published on 2021-11-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] Cluster Community coronavirus disease COVID-19 COVID-19 outbreak COVID-19 testing demonstrated Dormitory Evidence genomic Genomic surveillance implementation initiated limit Madison measure mild illness outbreak positive reduce respiratory infections rising SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Spread students subsequent tested Transmission United States university University of Wisconsin–Madison USA viruses whole-genome sequencing Wisconsin zoonoses [DOI] 10.3201/eid2711.211306 PMC 바로가기 [Article Type] Synopsis
Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2Articles Published on 2021-10-012022-10-30 Journal: The Lancet. Child & adolescent health [Category] COVID-19, MERS, SARS, [키워드] 1:1 age analysed Analysis Anosmia approach artificial Asymptomatic cause Characteristics children children with COVID-19 Cohort college Council COVID COVID-19 Department determine Engineering Epidemiological study fatigue finding foundation funding Gender greater groups headache heart illness illness duration illness onset imaging Innovation intelligence IQR King Limited London median Medical Research Council mild illness Older pandemic participant persistent positive Prevalence prospective cohort study reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test Science short duration Society Spearman Symptom symptom burden symptomatic Symptoms tested value Wellcome Trust were assessed were excluded [DOI] 10.1016/S2352-4642(21)00198-X PMC 바로가기 [Article Type] Articles