Association between HLA-C alleles and COVID-19 severity in a pilot study with a Spanish Mediterranean Caucasian cohort스페인 지중해 백인 코호트를 대상으로 한 파일럿 연구에서 HLA-C 대립형질과 COVID-19 심각성 사이의 연관성Article Published on 2022-08-122022-09-11 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, [키워드] age allele analyzed antiviral response association Asymptomatic cause Cell cell surface class Clinical characteristics clinical presentation Clinical presentations Cohort Comorbidity contrary COVID-19 COVID-19 severity Critical described determine disease epitope Epitopes expressed Factor fatal disease Gender groups HLA HLA allele HLA alleles HLA class I HLA-A HLA-B HLA-B allele HLA-B alleles HLA-C HLA-C allele HLA-C alleles HLA-C1 Host hyperinflammatory state immune response individual Infection involved KIR gene male management mechanism Mild mild infection no significant difference no significant differences outcomes pandemic peptide peptides pilot study recruited SARS-CoV-2 protein SARS-CoV-2 proteins significant difference significant differences small sample size Spain Spanish T cells β2-microglobulin [DOI] 10.1371/journal.pone.0272867 PMC 바로가기 [Article Type] Article
De-isolation of vaccinated COVID-19 health care workers using rapid antigen detection test신속한 항원 검출 테스트를 사용하여 백신 접종된 COVID-19 의료 종사자의 격리 해제Article Published on 2022-08-012022-09-11 Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] antigen detection approach Asymptomatic COVID-19 COVID-19 disease COVID-19 vaccination De-isolation described Diagnosis diagnosis of COVID-19 dose evaluate Evidence HCW HCWs Health care Health care worker health care workers increasingly Isolation Mild disease mild infection not different omicron Patient positive Rapid rapid antigen test required retrospective cohort study SARS-CoV-2 virus severe COVID-19 disease single center Symptom Vaccine variants viral kinetics viral shedding while with mild disease [DOI] 10.1016/j.jiph.2022.06.020 PMC 바로가기 [Article Type] Article
Quality of life, respiratory symptoms, and health care utilization 1 year following outpatient management of COVID-19: a prospective cohort study Research Published on 2022-07-292022-10-05 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] 95%CI adjusted assessment Care characterized cohort study COVID-19 determine employment EQ-5D Exercise limitation female Follow-up Health Impact IMPROVE independent Infection IQR likelihood Linear regression management median mild infection pathophysiology persistent primary care prospective cohort study Quality Quality of life reported Research respiratory symptom respiratory symptoms risk risk factor scored Sex significantly subject Symptom [DOI] 10.1038/s41598-022-17243-7 [Article Type] Research
Neonatal outcomes related to maternal SARS-CoV-2 infection in French Guiana: A case-control studyArticle Published on 2022-07-012023-07-09 Journal: Journal of infection and public health [Category] COVID19(2023년), [키워드] Breastfeeding low risk mild infection Newborn SARS-COV-2 positive mother. [DOI] 10.1016/j.jiph.2022.06.003 PMC 바로가기
Super Dominant Pathobiontic Bacteria in the Nasopharyngeal Microbiota Cause Secondary Bacterial Infection in COVID-19 Patients비인두 미생물총의 슈퍼 우세한 병원성 박테리아는 COVID-19 환자에서 2차 박테리아 감염을 유발합니다Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] 16S rRNA 16S rRNA gene abundance accounted Acinetobacter aggravate analyzed Bacterial Bacterial infection bacterial pneumonia bacterial specy cause collected Community composed coronavirus disease Coronavirus disease 2019 Corynebacterium Coverage COVID-19 COVID-19 infection COVID-19 patient defined difference disease severity Diversity dominant fatality genus High-throughput sequencing Infection Influenza invasive Lower respiratory tract lower respiratory tract samples microbiota Mild mild COVID-19 patients mild infection mild infections nasopharyngeal nasopharyngeal microbiota nasopharynx pathobiontic bacteria pathogen Patient patients patients with SARS-CoV-2 Pneumonia previous study respiratory infectious disease respiratory tracts responsible rRNA Sample SARS-COV-2 infection secondary secondary bacterial infection secondary bacterial pneumonia Seven severe COVID-19 Severe COVID-19 Infection severe COVID-19 patients severe group severe pneumonia significantly significantly higher Staphylococcus upper upper and lower respiratory tracts upper respiratory tract variety was used [DOI] 10.1128/spectrum.01956-21 PMC 바로가기 [Article Type] Article
A systematic review and meta-analysis of long term physical and mental sequelae of COVID-19 pandemic: call for research priority and action Reviews Published on 2022-06-062022-10-05 Journal: Molecular Psychiatry [Category] 바이오마커, [키워드] 95% CI abnormality acute COVID-19 acute infection Analysis Anxiety Cochrane Library cognitive Concentration conducted consequence country COVID-19 data extraction Depression dysfunction fatigue Gustatory Health higher risk impairment individual Infection Intervention Lung CT male management memory Mental Meta-analysis mild infection Neurological symptom observational study occurred Older participant persistence physical predictors Prevalence promote Psychiatric PTSD public health Pulmonary function test reported Research searched Severe infection Sleep disturbance suffered survivor Survivors Symptom Symptoms systematic review [DOI] 10.1038/s41380-022-01614-7 [Article Type] Reviews
Post-COVID-19 Fatigue and SARS-CoV-2 Specific Humoral and T-Cell Responses in Male and Female Outpatients남성 및 여성 외래 환자의 코로나19 이후 피로 및 SARS-CoV-2 특정 체액 및 T-세포 반응Article Published on 2022-05-262022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute COVID-19 acute infection Analysis assessment both sexes Clinical characteristics conducted Course COVID-19 development disease ELISA ELISPOT enzyme-linked immunosorbent evaluate Ex vivo examined fatigue female Germany humoral IFN-γ IFNγ IgG antibody IL-2 individual Inflammation interferon-γ Level male median time men mild infection not differ Outpatient outpatients participant pathophysiological mechanism producing response SARS-CoV-2 SARS-CoV-2-specific T-cell response scale Serum level significantly significantly lower Specific suffered T-cell T-cell Response T-cells treated university were measured women [DOI] 10.3389/fimmu.2022.902140 PMC 바로가기 [Article Type] Article
The changing dynamics of neutralizing antibody response within 10 months of SARS-CoV-2 infectionsSARS-CoV-2 감염 후 10개월 이내에 중화 항체 반응의 역학 변화Article Published on 2022-05-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Analysis average Comorbidity convalescent patient convalescent phase COVID-19 detectable determine discharge disease severity elicited Factor Follow-up Gender hospital humoral Humoral immunity Infection Inpatient investigated laboratory-confirmed long-term immunity majority mild infection mild infections mild patient mild patients multivariate NAb nAb response NAb titer NAb titers NAbs Neutralizing antibodies neutralizing antibody Neutralizing antibody response not affect parameter Patient predictor prospective cohort protective effect Re-infection Re-infections SARS-CoV-2 SARS-COV-2 infection serum sample serum samples significantly significantly higher the patient titers Virus neutralization was performed [DOI] 10.1002/jmv.27544 PMC 바로가기 [Article Type] Article
Poor Respiratory Health Following Relapsing SARS-CoV-2 Infection in Children with Cystic Fibrosis낭포성 섬유증이 있는 어린이의 SARS-CoV-2 감염 재발 후 불량한 호흡기 건강Article Published on 2022-04-012022-09-11 Journal: Indian journal of pediatrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] allergic bronchopulmonary allergic bronchopulmonary aspergillosis Asymptomatic bronchopulmonary aspergillosis children chronic lung disease clearance clearance of SARS-CoV-2 COVID-19 COVID-19 severity Cystic cystic fibrosis described develop diabete diabetes diagnosed fibrosis High-flow nasal oxygen intensive care lung Lung disease mild infection morbidity Noninvasive ventilation oxygen Pneumonia Poor Poor lung health Prolonged prolonged viral shedding recurrence respiratory Respiratory failure respiratory infection SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severe disease Support symptomatic disease [DOI] 10.1007/s12098-021-04057-0 PMC 바로가기 [Article Type] Article
Clinical Characteristics and Treatment Outcomes of Mild to Moderate COVID-19 Patients at Tertiary Care Hospital, Al Baha, Saudi Arabia: A Single Centre Study사우디 아라비아 Al Baha의 Tertiary Care Hospital에서 경증에서 중등도의 COVID-19 환자의 임상 특성 및 치료 결과: 단일 센터 연구Article Published on 2022-03-012022-09-11 Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 변종, 치료법, 치료제, [키워드] adhere Affect age analgesics anonymized data Antibiotic treatment Antibiotics Anticoagulant Antiviral Baha clinical Clinical outcome clinical outcomes Combination comorbid conditions coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 treatment Decision making diabetes Diabetes Mellitus effective effective decision making evaluated greater HCQ hospital Hydroxychloroquine hypertension Infection Intervention IQR maintain Mild mild infection mild to moderate mild to moderate symptoms mineral moderate mortality rate Mutation non-ICU non-ICU patient non-ICU patients past patients privacy protocol request Retrospective analysis Saudi Arabia severity of symptom Symptom Tertiary tertiary care hospital therapy treat treated Treatment Treatment outcome variant were given with COVID-19 Zinc [DOI] 10.1016/j.jiph.2022.02.001 PMC 바로가기 [Article Type] Article