Sequence similarity suggests molecular mimicry-induced cardiovascular symptoms in multisystem inflammatory syndrome in children (MIS-C)Article Published on 2022-10-012023-07-09 Journal: Immunology letters [Category] COVID19(2023년), [키워드] Coronavirus disease 2019 group A streptococcus molecular mimicry multisystem inflammatory syndrome in children severe acute respiratory syndrome coronavirus 2 [DOI] 10.1016/j.imlet.2022.07.002 PMC 바로가기
Reaction of SARS-CoV-2 antibodies with other pathogens, vaccines, and food antigensSARS-CoV-2 항체와 다른 병원체, 백신, 식품 항원의 반응Article Published on 2022-09-232022-11-15 Journal: Frontiers in Immunology [Category] SARS, 백일해, 진단, 파상풍, [키워드] antibodies antibody Antigen antigens autoantigen B cell Bacteria Bacterial BCG Blood casein Combination COVID-19 cross-protection cross-react cross-reactive antibody cross-reactivity DTaP elicit elicited experiment food antigens herpesviruses homology human tissues immune immune response immune system Immunity investigated memory T molecular molecular mimicry monoclonal monoclonal antibody pathogen Pathogens peptide polyclonal antibody Proteins reaction reactivity SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 spike protein shown similarity the SARS-CoV-2 virus Vaccine vaccine antigen Vaccines Viral antigen viruses [DOI] 10.3389/fimmu.2022.1003094 PMC 바로가기
Molecular Mimicry, Hyperactive Immune System, And SARS-COV-2 Are Three Prerequisites of the Autoimmune Disease Triangle Following COVID-19 InfectionReview Published on 2022-08-012022-10-05 Journal: International immunopharmacology [Category] SARS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] adaptive antiviral immune response autoantibody Autoimmune Autoimmune disease Autoimmunity clinical manifestations COVID-19 COVID-19 vaccine COVID‐19 disease Diseases drug effective Host Hyperactive Immune System immune immune system immune systems include induce mimicry molecular mimicry pandemic Pathogenesis Patient purpura SARS-CoV-2 SARS-COV-2 infection self-tolerance susceptible patients Symptom syndrome System systemic Thyroid tissue damage Treatment Triangle variety virus [DOI] 10.1016/j.intimp.2022.109183 [Article Type] Review
Case Report: Post-COVID-19 Vaccine Recurrence of Guillain-Barré Syndrome Following an Antecedent Parainfectious COVID-19-Related GBS증례 보고서: 코로나19 관련 GBS 이전의 Parainfectious COVID-19 관련 GBS에 따른 Guillain-Barré 증후군의 코로나19 이후 백신 재발Case Reports Published on 2022-07-182022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] Admission antecedent antibodies antibody Autoimmune Autoimmune diseases autonomic Case report causal link cerebrospinal fluid Combination complete recovery Course COVID-19 COVID-19 pneumonia COVID-19 symptoms COVID-19 vaccine cranial cranial nerves Diagnosis Diplopia disease dysfunction facial first dose Future ganglioside ganglioside antibodies. Guillain-barrè syndrome Guillain–Barrè syndrome ICU IgM immunoglobulins Intravenous immunoglobulin IVIG mechanisms molecular mimicry Neurological disorder observation occurred Patient Pfizer Pfizer/BioNTech Pneumonia recurrence reported SARS-CoV-2 seropositive Seropositivity syndrome therapy unique Vaccinations Vaccine Viral Viral illness viral illnesses weakness [DOI] 10.3389/fimmu.2022.894872 PMC 바로가기 [Article Type] Case Reports
Potential Autoimmunity Resulting from Molecular Mimicry between SARS-CoV-2 Spike and Human ProteinsSARS-CoV-2 스파이크와 인간 단백질 간의 분자 모방으로 인한 잠재적 자가면역Article Published on 2022-06-282022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Adverse reactions AlphaFold2 antibody Antibody binding Asymptomatic Autoimmune Autoimmunity calcium cardiac disease cause coronavirus coronavirus SARS-CoV-2 COVID-19 COVID-19 complication COVID-19 complications COVID-19 pathogenesis COVID-19 patients cross-reacting antibodies disease disorder Epitopes example explanation highlight host protein host proteins hotspot Human human proteins implication induce investigated involved machine learning mimicry molecular molecular dynamics molecular mimicry motif omicron outcomes platelet activation Potential PRKG1 Protein protein structure protein structure comparison reduce Regulation resulting SARS-CoV-2 SARS-CoV-2 spike spike Symptom therapeutic intervention therapeutic interventions thrombocytopenia Thrombopoietin tropomyosin Vaccine Vaccine design variant Viral Viral antigen viral antigens [DOI] 10.3390/v14071415 PMC 바로가기 [Article Type] Article
SARS-CoV-2 triggering autoimmune diseases자가 면역 질환을 유발하는 SARS-CoV-2Review Published on 2022-06-012022-09-11 Journal: Cytokine [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] acquired immunity Activation acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ARDS autoantibody autoimmune antibodies Autoimmune disease Autoimmunity autoreactivity bystander caused CD4 CD8 chronic inflammation contribute coronavirus COVID-19 COVID-19 pandemic cytokine cytokine secretion Cytokine storm element elicit Evidence high mortality Hyperactivation Hyperstimulation immune response immune system Immunity immunological Immunosuppression Inflammation mechanism molecular molecular interaction molecular mimicry pandemic Patient respiratory respiratory distress Respiratory distress syndrome respiratory epithelium SARS-CoV-2 scarcity self-tolerance severe acute respiratory syndrome Coronavirus syndrome T cells the disease thought Trigger triggering triggers variety virus viruses [DOI] 10.1016/j.cyto.2022.155873 PMC 바로가기 [Article Type] Review
Antigenic Cross-Reactivity Between SARS-CoV-2 S1-RBD and Its Receptor ACE2SARS-CoV-2 S1-RBD와 수용체 ACE2 간의 항원 교차 반응성Article Published on 2022-05-042022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] ACE2 acute respiratory syndrome addition amino acid residue Analysis analyzed angiotensin converting enzyme 2 angiotensin-converting enzyme 2 anti-ACE2 antibody antibody Antibody binding antigenic autoantibody bind binding Control coronavirus COVID-19 COVID-19 pandemic COVID-19 patient Critical cross-react cross-reactivity denatured disease severity docking domain enzyme epitope higher affinity human cell increase in indicated mAb measurement mechanism mice molecular molecular mimicry monoclonal antibody overlapping patients with COVID-19 peptide positive correlation protein-protein interaction receptor receptor ACE2 recognize responsible SARS-CoV-2 SARS-COV-2 infection sera Serum level significantly significantly higher the binding affinity the S1 subunit the spike protein transmission electron microscopy virus western blotting [DOI] 10.3389/fimmu.2022.868724 PMC 바로가기 [Article Type] Article
SARS-CoV-2 and human retroelements: a case for molecular mimicry?Article Published on 2022-04-082023-07-08 Journal: BMC Genomic Data [Category] COVID19(2023년), [키워드] Autoimmunity Coronaviruses COVID-19 epitope signatures Endogenous retroviruses (ERV) Human retroelements Long interspersed nuclear elements (LINE) molecular mimicry SARS-CoV-2 [DOI] 10.1186/s12863-022-01040-2 PMC 바로가기
Identification and characterization of novel RdRp and Nsp15 inhibitors for SARS-COV2 using computational approach컴퓨터 접근 방식을 사용한 SARS-COV2에 대한 새로운 RdRp 및 Nsp15 억제제의 식별 및 특성화Article Published on 2022-04-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] active site acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alectinib approach caused Compound coronavirus COVID-19 COVID19 different disease different diseases drug Drug repurposing effective inhibitor EndoU enzyme Ergotamine health emergency Health Organization highlight homology homology modeling hydrogen Hydrogen bond hydrophobic identification inhibitor inhibitors Interaction MD simulation molecular molecular interaction molecular mimicry Naldemedine Nsp15 observé pathogen performed Protein target RdRP residue RNA RNA dependent RNA polymerase RNA polymerase SARS-CoV-2 selected severe acute respiratory syndrome Coronavirus Therapeutics Virtual screening were used World Health Organization [DOI] 10.1080/07391102.2020.1841026 PMC 바로가기 [Article Type] Article
Myocarditis following COVID-19 vaccination: incidence, mechanisms, and clinical considerationsReview Published on 2022-04-012023-07-08 Journal: Expert review of cardiovascular therapy [Category] COVID19(2023년), [키워드] clinical COVID-19 in vitro transcribed mRNA incidence innate immune system molecular mimicry myocarditis Vaccine [DOI] 10.1080/14779072.2022.2066522 PMC 바로가기 [Article Type] Review