The TLR-NF-kB axis contributes to the monocytic inflammatory response against a virulent strain of Lichtheimia corymbifera, a causative agent of invasive mucormycosisArticle Published on 2022-10-132022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] 24 hours activated Activation Apoptosis apoptotic cascade caused Cell cell damage characterized contribute COVID-19 CTLs Cytokines Diabetes Mellitus Diagnosis Diseases ENhance exhibit fungal Fungal infection fungi Hematological malignancies host cell Host immune response host inflammatory response host-pathogen interactions human monocyte human monocytes IL-1β IL-6 increase in individual Infection Inflammatory Inflammatory response inflammatory signaling Interaction invasive killing life-threatening modulation monocyte mortality rate Mucorales Mucormycosis NF-kB Occurrence organ pathogenic phagocyte phagocytosis priming pro-inflammatory cytokine produced progression PRRs receptor receptors receptors. regulate secreted signaling pathway spore susceptible synergistic therapy TLR TLR4 TLRs TNF-α Toll-like receptor transcription factor virulent [DOI] 10.3389/fimmu.2022.882921 PMC 바로가기
Clinical phenotypes and outcomes associated with SARS-CoV-2 variant Omicron in critically ill French patients with COVID-19Article Published on 2022-10-122022-11-16 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, [키워드] 28-day mortality adjusted odds ratio association clinical clinical condition clinical phenotype Critically ill Delta dose Factors France French humoral Immunocompromised Immunocompromised patient Infection information intensive care intensive care unit less mortality rate multicenter observé Occurrence omicron outcome Patient patients patients with COVID-19 phenotype prospective cohort study response to vaccination SARS-CoV-2 variant severe COVID-19 severe disease severity significantly higher Vaccine variant viral genome [DOI] 10.1038/s41467-022-33801-z PMC 바로가기
Estimation of biochemical factors affecting survival in intensive care COVID-19 patients undergoing chest CT scoring: A retrospective cross-sectional studyArticle Published on 2022-10-072022-11-16 Journal: Medicine [Category] 변종, [키워드] 95% CI Affect affecting age APACHE II APACHE II score approval biochemical Blood urea nitrogen changed Chest computed tomography Chest CT chest CT scan conducted Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Data analysis determine died estimation ethics committee Factor faculty females Follow-up greater Health ICU intensive care Invasive mechanical ventilation laboratory parameter males marker Mortality mortality rate no significant difference nonsurvivor nonsurvivors pandemic Patient PCR PCR test polymerase chain positive Prognosis ranged Respiratory disease Retrospective cross-sectional study significantly SPSS survival survivor symptomatic patient the mean the patient the WHO Transmission university variant was used were recorded widespread window Wuhan [DOI] 10.1097/MD.0000000000030407 PMC 바로가기
Does baricitinib reduce mortality and disease progression in SARS-CoV-2 virus infected patients? A systematic review and meta analysisArticle Published on 2022-10-012022-11-15 Journal: Respiratory medicine [Category] COVID19(2023년), SARS, 진단, [키워드] analysed analyses Analysis article Baricitinib clinical trial COVID-19 COVID-19 patients database Disease progression Efficacy evaluate fixed Google Scholar heterogeneity inclusion criteria management Meta-analysis meta-analysis Mortality mortality rate Newcastle-Ottawa Scale NOS PROSPERO random effect model randomised RCTs reduce reduce mortality reduced risk risk of bia RoB SARS-CoV-2 virus searched significantly square statistically systematic review systematic review. Trial [DOI] 10.1016/j.rmed.2022.106986 PMC 바로가기
Impact of SARS-CoV-2 viral load and duration of symptoms before hospital admission on the mortality of hospitalized COVID-19 patientsArticle Published on 2022-10-012022-11-15 Journal: Infection [Category] COVID19(2023년), SARS, 치료제, [키워드] Admission Analysis antivirals clinical manifestation collected COVID-19 COVID19 Ct value cycle threshold Day Days of symptoms demographic duration of symptom Efficacy evaluate Factor Factors highest Hospital admission hospitalized COVID-19 patient hospitalized patient identify Impact Inclusion laboratory parameter Mortality mortality rate multivariate analysis Nasopharyngeal swab Patient performed positive predictor reverse transcription rRT-PCR SARS-CoV-2 viral load study population symptoms onset three group Viral load Viral load. was performed [DOI] 10.1007/s15010-022-01833-8 PMC 바로가기
Stratification of patients admitted for SARS-CoV2 infection: prognostic scores in the first and second wave of the pandemicArticle Published on 2022-10-012023-07-09 Journal: Internal and Emergency Medicine [Category] COVID19(2023년), [키워드] COVID-19 mortality rate prognostic scores respiratory failure. [DOI] 10.1007/s11739-022-03016-7 PMC 바로가기
SARS-COV-2/COVID-19: scenario, epidemiology, adaptive mutations, and environmental factorsArticle Published on 2022-10-012022-11-16 Journal: Environmental science and pollution research inter [Category] COVID19(2023년), SARS, 변종, [키워드] adaptive bat contaminated surface coronavirus COVID-19 droplet environmental factor environmental factors Epidemiology Evolution explain Genetic globe Health threat human infection human-to-human transmission humans involved key factor mortality rate mutations origin overcome pandemic pangolin pathogen predicted SARS-CoV-2 SARS-CoV-2 variant Transmission variants. virus while worldwide pandemic [DOI] 10.1007/s11356-022-22333-0 PMC 바로가기
Risk factors for disease severity and mortality of children with Covid-19: A study at a Vietnamese Children’s hospitalResearch article Published on 2022-10-012022-10-05 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] age children children with COVID-19 close contact Comorbidities confirmed case COVID-19 COVID-19 case COVID-19 cases COVID-19 patients CRP died disease disease severity Dyspnea elevated Factor ferritin hospital independent Inflammatory marker Invasive mechanical ventilation male Mild moderate Mortality mortality rate neurologic Patient pediatric pediatrics positive positive RT-PCR Respiratory Support Result retrospective cohort study risk factor Risk factors RT-PCR SARS-CoV-2 severity treated Treatment underlying disease underlying diseases was performed [DOI] 10.1016/j.jiac.2022.06.010 [Article Type] Research article
Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi ArabiaCase report Published on 2022-10-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 치료기술, 치료제, [키워드] absence Case report Child children clinical outcomes Complication COVID-19 differential diagnosis Encephalopathy Favipiravir Health immunosuppressive therapy impacted knowledge Laboratory manifested maternity morbidities mortality rate neurologic pandemic Patient patient with COVID-19 pediatric Pediatric patients presenting pulse recovered completely reported respiratory manifestations respiratory symptoms routine Saudi Arabia Seizure status epilepticus symptomatic the patient Therapies with COVID-19 [DOI] 10.1016/j.ijid.2022.08.013 [Article Type] Case report
Lactate dehydrogenase/albumin ratio as a prognostic factor in severe acute respiratory distress syndrome cases associated with COVID-19Article Published on 2022-09-232022-11-15 Journal: Medicine [Category] 바이오마커, [키워드] acute respiratory distress Admission affected affecting Analysis ARDS AUC Biomarker C-reactive protein calculated can be used caused characteristic Clinical characteristics confidence interval COVID 19 COVID-19 COVID-19 diagnosis determine early stages evaluated Factors FIVE high mortality hospital ICU in-hospital mortality independent independent risk factor intensive care laboratory result lactate dehydrogenase LDH lung damage marker Mortality mortality rate multivariate logistic regression Patient patients hospitalized predict predicted Prognosis prognostic biomarker Prognostic factor regression analysis severe ARDS syndrome Tertiary the patient was performed were recorded with COVID-19 [DOI] 10.1097/MD.0000000000030759 PMC 바로가기