Effectiveness of a Self-Management Program to Improve Cognition and Quality of Life in Epilepsy: A Pragmatic, Randomized, Multicenter TrialRandomized Controlled Trial Published on 2022-05-242022-10-05 Journal: Neurology [Category] 임상, [키워드] age Analysis baseline Care change class classification Cognition Cognitive impairment conducted Control controls COVID-19 pandemic demonstrated determine Effectiveness Efficacy England epilepsy Evidence feasibility female Future group Health IMPROVE improvement Intervention intervention group life Long-term follow-up measure Modification multisite New outcome Pairwise comparison participant Pragmatic Program provide Quality Quality of life recruited replicated Replication Research significantly training Treatment Trial were assessed [DOI] 10.1212/WNL.0000000000200346 PMC 바로가기 [Article Type] Randomized Controlled Trial
Analyzing changes in radiotherapy treatment planning error reporting during the COVID-19 pandemicResearch article Published on 2022-04-112022-10-05 Journal: Medical Dosimetry [Category] 치료법, [키워드] affected Cancer Care change changed changes in coronavirus COVID-19 COVID-19 pandemic database determine Efficiency Error reporting event Frequency Health implementation Incident reporting multisite oncology pandemic Radiation radiation therapy Radiotherapy Remote treatment planning reported significant increase Treatment [DOI] 10.1016/j.meddos.2022.04.001 [Article Type] Research article
The effect of national public health measures on the characteristics of trauma presentations to a busy paediatric emergency service in Ireland: a longitudinal observational studyObservational Study Published on 2022-04-012022-10-05 Journal: Irish Journal of Medical Science [Category] COVID19(2023년), SARS, 임상, [키워드] addressed aligned carried Characteristics COVID-19 Final impacted initial Injury Injury prevention lockdown multisite National occurred Paediatric emergency medicine progressed public health public health measure reached reduced reduction in reductions in Regional retrospective reveal SARS-CoV-2 SARS-CoV-2 pandemic significant increase trauma [DOI] 10.1007/s11845-021-02593-4 PMC 바로가기 [Article Type] Observational Study
Reverse-Transcription Loop-Mediated Isothermal Amplification Has High Accuracy for Detecting Severe Acute Respiratory Syndrome Coronavirus 2 in Saliva and Nasopharyngeal/Oropharyngeal Swabs from Asymptomatic and Symptomatic Individuals역전사 루프 매개 등온 증폭은 무증상 및 무증상 개인의 타액 및 비인두/구인두 면봉에서 중증 급성 호흡기 증후군 코로나바이러스 2를 감지하는 데 높은 정확도를 제공합니다Article Published on 2022-04-012022-09-11 Journal: The Journal of molecular diagnostics : JMD [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Asymptomatic asymptomatic individual Asymptomatic individuals Care clinical evaluation Community coronavirus coronavirus 2 described diagnostic diagnostic sensitivity diagnostic specificity Direct extracted RNA extraction Health Health care individual isothermal amplification Loop-mediated isothermal amplification multisite ORF1 ORF1ab Previous studies previous study Quantitative Quantitative RT-PCR respiratory RNA RT-LAMP RT-PCR RT-qPCR Saliva saliva samples SARS-CoV-2 SARS-CoV-2 detection sensitivity severe acute respiratory syndrome Coronavirus specificity Swab swabs symptomatic symptomatic individual variety was performed [DOI] 10.1016/j.jmoldx.2021.12.007 PMC 바로가기 [Article Type] Article
Safety and efficacy of transcranial direct current stimulation in upper extremity rehabilitation after tetraplegia: protocol of a multicenter randomized, clinical trial Research Published on 2022-03-052022-10-05 Journal: Spinal cord [Category] 임상, [키워드] acquisition activity adverse events Affair age anodal assessment assigned attrition baseline center Cleveland clinic clinical trial Combination conducted CORD corticospinal Direct Current domain double-blinded Efficacy evaluate evaluated feasibility Follow-up foundation functional impairment measure MetroHealth multicenter multisite New noninvasive objective occupational occurred outcome outcome measure paretic participant performance performed promote protocol Randomized Randomly receive rehabilitation Safety secondary self-care sensibility separated setting spinal Spinal cord injury Street strength Trial upper veteran [DOI] 10.1038/s41393-022-00768-z [Article Type] Research
SPEAKS study: study protocol of a multisite feasibility trial of the Specialist Psychotherapy with Emotion for Anorexia in Kent and Sussex (SPEAKS) intervention for outpatients with anorexia nervosa or otherwise specified feeding and eating disorders, anorexia nervosa typeSPEAKS 연구: 신경성 식욕 부진증 또는 달리 명시된 섭식 및 섭식 장애, 신경성 식욕 부진 유형이 있는 외래 환자를 위한 Kent and Sussex의 거식증 감정에 대한 전문 심리 치료(SPEAKS) 중재의 다중 사이트 타당성 시험 연구 프로토콜Article Published on 2022-02-222022-09-11 Journal: BMJ Open [Category] COVID19(2023년), SARS, 임상, [키워드] acceptability access adult psychiatry Analysis anorexia anorexia nervosa change choice coding collected conferences COVID-19 pandemic develop disorder disorders Eating Disorder eating disorders education emotion emotional Ethical approval Ethics ethics committee feasibility high mortality rate higher education hypothese hypotheses hypothesised inclusion criteria inherent initial Intervention life measure Measures mental health multisite national guidelines National Health Service NHS nine offered Open Access outcome Outpatient participant peer-reviewed protocol provided psychotherapy qualitative research Quality of life randomised controlled trial recorded recruitment registration number Research Research Ethics resulting Sample size significantly single-arm specialist Study protocol Support Symptom Tau therapy Treatment Trial trial ended Trust [DOI] 10.1136/bmjopen-2021-050350 PMC 바로가기 [Article Type] Article
Descriptive comparison of admission characteristics between pandemic waves and multivariable analysis of the association of the Alpha variant (B.1.1.7 lineage) of SARS-CoV-2 with disease severity in inner London전염병 파동 사이의 입원 특성과 SARS-COV-2의 알파 변이체 (B.1.1.7 계보)의 연관성 분석 및 런던 내부의 질병 중증도의 다변량 분석.Infectious Diseases Published on 2022-02-082022-09-10 Journal: BMJ Open [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, [키워드] 1.26 95% CI Admission age aligned Alpha Alpha variant Analysis association B.1.1.7 B.1.1.7 lineage Characteristics circulating clinical Clinical data Cohort collected current defined disease severity dominant Electronic health record Epidemiology Health health record healthcare hospitalised hypoxia Infection infection control Intervention isolate Laboratory Logistic regression London multisite multivariable analysis Multivariate analysis nosocomial obesity on admission pandemic positive public health Result risk factor Risk factors SARS-CoV-2 SARS-CoV-2 RNA sequence sequenced severity Severity of disease variant Viral viral genome sequence Virology Wave [DOI] 10.1136/bmjopen-2021-055474 PMC 바로가기 [Article Type] Infectious Diseases
Clotting events among hospitalized patients infected with COVID-19 in a large multisite cohort in the United StatesResearch Article Published on 2022-01-052022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] anticoagulation arterial benefit blood clot clotting Cohort COVID-19 COVID-19 disease COVID-19 infection COVID-19 patients COVID-19 vaccine death diabetes event examined Factor Gender highlight hospital hospitalized COVID-19 patient hospitalized patient ICU illnesses increase increased risk infected with COVID-19 Infection Influenza influenza infection intensive care male material multisite Occurrence Older age patients hospitalized patients with COVID-19 progression rates of admission Result risk the United State thrombosis vaccination venous Venous thrombosis [DOI] 10.1371/journal.pone.0262352 PMC 바로가기 [Article Type] Research Article
Combined epidemiological and genomic analysis of nosocomial SARS-CoV-2 infection early in the pandemic and the role of unidentified cases in transmission전염병 초기 병원 SARS-CoV-2 감염의 역학 및 게놈 통합 분석과 전염에서 미확인 사례의 역할Article Published on 2022-01-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission Admissions analysed Asymptomatic asymptomatic patients case ascertainment Cluster Clusters Combined Community consecutive patients coronavirus Coronavirus 2019 COVID-19 creating Diagnosis early stage early stages epidemiological epidemiological data epidemiologically Evidence evidence of Face mask Face masks facilitated Factor Final genome sequence Genomic analysis genomic data Genomics Haplotype healthcare healthcare worker Healthcare workers Healthcare-associated infection hospital implicated incidence increase infection control limit median Molecular epidemiology multisite nosocomial Nosocomial transmission pandemic per day positive PCR test respiratory SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-COV-2 infection sequenced Sequencing severe acute respiratory syndrome Coronavirus Support Transmission transmission cluster transmission clusters vector Viral viral genome sequence whole-genome sequencing with infection [DOI] 10.1016/j.cmi.2021.07.040 PMC 바로가기 [Article Type] Article
Durability of SARS-CoV-2-Specific T-Cell Responses at 12 Months PostinfectionArticle Published on 2021-12-152022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 바이오마커, 진단, 치료기술, [키워드] 12 months acute illness acute respiratory syndrome age antibody CD4 T cell Cellular immune response cellular response clinical outcomes coronavirus coronavirus disease COVID-19 Cytotoxic T cell cytotoxicity detectable disease disease severity Durability ENhance flow cytometry Frequency identify Immunity induce Infection influence intracellular cytokine staining investigated magnitude memory memory T cell Month multisite natural infection participant Peripheral blood Phenotypes polyfunctionality Postinfection prospective cohort study representing response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody SARS-CoV-2-specific T cell severe disease T cell therapeutic interventions [DOI] 10.1093/infdis/jiab543 PMC 바로가기