Detection of SARS-CoV-2 in different human biofluids using the loop-mediated isothermal amplification assay: A prospective diagnostic study in Fortaleza, Brazil루프 매개 등온 증폭 분석을 사용하여 다양한 인간 생체 유체에서 SARS-CoV-2 검출: 브라질 Fortaleza의 전향적 진단 연구Article Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adopted biofluid Brazil caused Chain Reaction collected coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 detect detection Diagnosis diagnostic evaluated gold gold standard human gene isothermal amplification LAMP Loop-mediated isothermal amplification management Molecular diagnosis Nasopharyngeal swab nasopharyngeal swabs ORF1 ORF1ab oropharyngeal swabs pandemic Patient polymerase chain polymerase chain reaction primer primer set Primers processed Quantitative quantitative polymerase chain reaction RT-LAMP RT-qPCR SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus specificity [DOI] 10.1002/jmv.27842 PMC 바로가기 [Article Type] Article
Rapid and qualitative identification of SARS-CoV-2 mutations associated with variants of concern using a multiplex RT-PCR assay coupled with melting analysisArticle Published on 2022-09-012022-11-16 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] amplified Analysis Beta characterized Complete Concordance contributing to Delta detect Direct E484K examined expected faster Gamma Genetic variant L452R melting Melting analysis multiplex Mutation mutations N501Y Nasopharyngeal swab nasopharyngeal swabs omicron positive public health Rapid Rapid identification RT-PCR RT-PCR assay Sanger method Sanger sequencing SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 variants sensitivity Sensitivity and specificity Seven specificity Spread Surveillance the SARS-CoV-2 variant variants of concern Viral load was performed [DOI] 10.1016/j.ijid.2022.06.032 PMC 바로가기
COVID salivary diagnostics: A comparative technical studyCOVID 타액 진단: 비교 기술 연구Article Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assumption can be used Care Chain Reaction coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 Delta diagnostic diagnostics direct methods eliminating envelope golden standard heat heat-released RNA high accuracy indicate individuals infected individual infected individuals Intervention Isolation mass mass surveillance molecular molecular diagnostics Mouthwash nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs noninvasive NPs Open reading frame open reading frame 1 open reading frame 1ab ORF1ab pandemic patients polymerase chain polymerase chain reaction promote remained reported respiratory restriction RNA RNA extraction robust RT-PCR Saliva salivary sampling SARS-CoV-2 sensitivity severe acute respiratory syndrome Coronavirus specificity Surveillance the patient Viral viral gene viral genes virus spread while widespread [DOI] 10.1002/jmv.27883 PMC 바로가기 [Article Type] Article
Mass testing of healthcare workers for COVID-19-A single institution experience in Sabah, East MalaysiaCOVID-19-동말레이시아 사바에서 단일 기관 경험에 대한 의료 종사자의 대규모 테스트Article Published on 2022-08-252022-09-11 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] Asymptomatic Compliance conducted Contact COVID-19 COVID-19 case COVID-19 infection COVID-19 testing COVID-19 transmission Daily temperature Early detection East effective exposure to had no HCW HCWs healthcare worker Healthcare workers high-risk area high-risk areas hospital Infection involved laboratory result majority Malaysia mass Nasopharyngeal swab nasopharyngeal swabs Nurse Nurses Personal protective equipment positive PPE prevention of COVID-19 reported Strategy stratified study period Symptom symptomatic and asymptomatic through contact time interval Transmission Travel [DOI] 10.1371/journal.pone.0273326 PMC 바로가기 [Article Type] Article
High Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Household Transmission Rates Detected by Dense Saliva Sampling고밀도 타액 샘플링으로 감지된 고중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2) 가구 전파율Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Analysis attack rate calculated capillary blood capillary blood samples children collected coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 Dense enrolled highest household household transmission Households independent index case individuals infection control investigated majority measure nasopharyngeal swabs not affected NPs oropharyngeal swab oropharyngeal swabs pandemic phylogenetic analyses polymerase chain polymerase chain reaction positive Rate Real-time monitoring repeated reported Research respiratory Saliva saliva sample saliva samples sampling SAR SARS-CoV-2 SARS-CoV-2 transmission secondary attack rate secondary case secondary cases serology serum serum sample severe acute respiratory syndrome Coronavirus study inclusion suggested Swab tested understanding vaccination was performed Whole genome sequencing [DOI] 10.1093/cid/ciac261 PMC 바로가기 [Article Type] Article
Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults비인두 미생물군집의 연령 관련 변화는 소아, 청소년 및 젊은 성인의 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 감염 및 증상과 관련이 있습니다Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 유전자 메커니즘, [키워드] 16S ribosomal RNA Adults age association Bacterial change Characteristics childhood children Clinical data collected coronavirus 2 Corynebacterium Course COVID-19 Defense Dolosigranulum evaluated Factor feature generalized joint attribute modeling Host host defense identify Illness severity increasingly infected individuals influence joint less magnitude mechanism Microbiome microbiome composition microbiota nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs participant Pathogens pediatric pediatric microbiota. profile respiratory Respiratory pathogens respiratory symptom respiratory symptoms SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility SARS-CoV-2-infected individual SARS-CoV-2-infected individuals Sequencing susceptibility susceptible Symptom upper respiratory [DOI] 10.1093/cid/ciac184 PMC 바로가기 [Article Type] Article
Medico-demographic characteristics and outcomes of COVID-19 patients admitted to a provincial hospital in Center-West of MoroccoArticle Published on 2022-08-102022-11-16 Journal: The Pan African Medical Journal [Category] SARS, 치료기술, [키워드] Admission Analysis analyzed cardiac disease CFR Characteristics China Clinical characteristics collected Comorbidities conducted confirmed COVID-19 case cough COVID-19 COVID-19 cohort COVID-19 patient cross-sectional death deaths Deceased defined diabete disease Dyspnea Factor female Fever help hospital Hospitalization hypertension identify In-hospital less Logistic regression analysis males median age men Morocco Mortality mortality rates Most patient multivariate logistic regression nasopharyngeal swabs Older Older age outcome oxygen saturation pandemic Patient performed positive prevalent real-time RT-PCR reduce reported risk risk factor SARS-CoV-2 SARS-CoV-2 genome SPSS Symptom symptomatic was performed [DOI] 10.11604/pamj.2022.42.268.35427 PMC 바로가기
SARS-CoV-2 infection risk among vaccinated and unvaccinated household members during the Alpha variant surge – Denver, Colorado, and San Diego, California, January-April 2021알파 변종 급증 시 백신 접종 및 미접종 가구 구성원 간의 SARS-CoV-2 감염 위험 - 콜로라도주 덴버 및 캘리포니아주 샌디에이고, 2021년 1월-4월Article Published on 2022-08-052022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Alpha Alpha variant antibody Asymptomatic B.1.1.7 Blood collected Community conducted confidence confidence interval Contact COVID-19 COVID-19 vaccination Culture Cycle threshold values Diego Effectiveness eligible enrolled Epsilon Evidence examined highlight household household contact household contacts household transmission Households incidence individual infection risk infection risks information interval Lineage nasopharyngeal swabs predominant proportion protective effect reduce reported risk RT-PCR SARS-CoV-2 SARS-CoV-2 B.1.1.7 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 variant secondary case secondary cases Support symptomatic Transmission vaccination vaccine effectiveness variant variants [DOI] 10.1016/j.vaccine.2022.06.066 PMC 바로가기 [Article Type] Article
CFD based analysis of 3D printed nasopharyngeal swabs for COVID-19 diagnosticsResearch article Published on 2022-08-012022-10-05 Journal: Computer methods and programs in biomedicine [Category] 진단, [키워드] 3D printing Additive Additive manufacturing Analysis approach assist CFD clinical testing clinical trial comparable Computational Fluid Dynamics (CFD) conditions conducted COVID-19 COVID-19 testing criteria diagnostics domain Efficacy Efficiency evaluate experiment geometric IMPROVE nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs NP swab NP swabs objective parameter predicted Result significant changes in Swab swabs Taguchi method Variability Volume Volume of Fluid method [DOI] 10.1016/j.cmpb.2022.106977 [Article Type] Research article
Repeated transmission of SARS-CoV-2 in an overcrowded Irish emergency department elucidated by whole-genome sequencing전체 게놈 시퀀싱으로 밝혀진 과밀 아일랜드 응급실에서 SARS-CoV-2의 반복 전파Article Published on 2022-08-012022-09-11 Journal: The Journal of hospital infection [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis assigned B.1.1.7 B.1.1.7 lineage bioinformatics Chain Reaction Cluster Community complex consensus genome Contact tracing COVID COVID-19 COVID-19 pandemic defined demonstrated effort emergency department epidemiologically Genomic epidemiology hospital Hospital overcrowding hospital ward Infection infections Limerick Local maximum-likelihood nasopharyngeal swabs occurred outbreak Outbreak investigation Oxford pangolin Patient Phylogenetic tree polymerase chain polymerase chain reaction Prevent Prevention and control protocol resulting reverse transcriptase SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections sequence Sequencing Single nucleotide polymorphism SNPs surveillance testing threshold transcriptase Transmission transmission of SARS-CoV-2 university Viral RNA viral RNA extracted Viral transmission was performed WGS whole-genome sequencing [DOI] 10.1016/j.jhin.2022.04.015 PMC 바로가기 [Article Type] Article