GENERATING RESPONSES IMMUNE IN CELLULAR AND HUMORAL TREATMENT WITH EPITOPE SPIKE, EPITOPE ENVELOPE PROTEIN, AND EPITOPE MEMBRANE PROTEIN SARS-COV-2, HONEY, SAUSSUREA LAPPA , AND NIGELLA SATIVA에피토프 스파이크, 에피토프 봉투 단백질 및 에피토프 막 단백질 SARS-COV-2, Honey, Saussurea Lappa 및 Nigella Sativa로 세포 및 체액 처리에서 면역을 생성합니다.Article Published on 2021-09-012022-09-10 Journal: African Journal of Infectious Diseases [Category] 비임상, [키워드] Sausseria lappa administration animal model breath Cellular immune response cellular immune responses cellular immunity clinical trial COVID-19 CPE CTL domination envelope protein epitope evaluated four group four groups Honey humoral immune response Humoral immunity IgG IL-4 immune responses immunomodulator Indonesia lung marker material membrane protein mice mouth Nigella Sativa NK cell NK cells organ pandemic PBS Placebo Research Respons immune Spike protein TGF-β β-defensin [DOI] 10.21010/ajidv15i2S.3 PMC 바로가기 [Article Type] Article
Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trialControlled Trial Published on 2021-09-012023-07-02 Journal: Complementary therapies in medicine [Category] SARS, [키워드] COVID-19 herbal medicine Nigella Sativa SARS-CoV-2 [DOI] 10.1016/j.ctim.2021.102769 PMC 바로가기 [Article Type] Controlled Trial
Pharmacological Effects of Selected Medicinal Plants and Vitamins Against COVID-19Article Published on 2021-07-182022-10-29 Journal: Journal of food and nutrition (Frisco, Tex.) [Category] COVID-19, [키워드] acute respiratory syndrome Against Allium allium sativum Anti-viral antiviral activities antiviral activity antiviral property benefit caused center clinical confirmed case Control coronavirus disease Coronavirus-2 country COVID-19 COVID-19 patients Curcumin database death deaths disease disrupt Effect ENhance Google Scholar Health Human immune system IMPROVE medicinal plants Nigella Sativa ongoing trial Pharmacological Effects plant Prevent prevention promote PubMed Central registry Replication SARS-CoV-2 searched selected shown the SARS-CoV-2 Treatment Vitamin Vitamin C Vitamin D World Health Organization Zingiber Zingiber Officitale [DOI] 10.17303/jfn.2021.7.202 PMC 바로가기 [Article Type] Article
Possible therapeutic effects of Nigella sativa and its thymoquinone on COVID-19Covid-19에 대한 Nigella sativa와 Thymoquinone의 가능한 치료 효과Review Published on 2021-06-102022-08-31 Journal: Pharmaceutical Biology [Category] SARS, 치료제, [키워드] animal Anti-inflammatory Antiviral antiviral effects cause Clinical studies clinical study clinical trial clinical trials Context COVID-19 database Effect Effects Efficacy flowering plant Google Scholar IFN-γ IgG1 IgG2a IL-12 IL-2 IL-4 IL-6 immunomodulation immunomodulatory effect immunomodulatory effects immunomodulatory properties immunomodulatory property infected patient infected patients ISI literature review mediators medicinal plant molecular docking Nigella Sativa Novel coronavirus objective Preliminary data pro-inflammatory mediator pro-inflammatory mediators Pulmonary function test randomize reduced respiratory respiratory disorders Respiratory system Result searched Serum level serum levels Severe infection suggested therapeutic effect thymoquinone Treatment Web of Science with COVID-19 [DOI] 10.1080/13880209.2021.1931353 PMC 바로가기 [Article Type] Review
Potential influence of Nagella sativa (Black cumin) in reinforcing immune system: A hope to decelerate the COVID-19 pandemic면역 체계 강화에 Nagella sativa(블랙 커민)의 잠재적인 영향: COVID-19 전염병을 늦추기 위한 희망Review Published on 2021-05-012022-08-31 Journal: Phytomedicine : international journal of phytother [Category] SARS, 신약개발, 치료제, [키워드] acute respiratory distress syndrome Anti-inflammatory antioxidant ARDS benefit black Black seed component components coronavirus COVID-19 COVID-19 pandemic COVID-19 patient Critical Cytokines disease severity Effect Evidence FDA approved Drugs human body immune immune modulation immune regulation immune response immune system immunomodulation indicated infected with COVID-19 intensive care intensive care unit modulation molecular molecular docking Molecular docking study Mortality Nagella sativa New coronavirus Nigella Sativa Nigellidine Obstructive pandemic pathophysiology Patient Potential pro-inflammatory cytokine pro-inflammatory cytokines provided respiratory respiratory disorders respiratory distress Respiratory distress syndrome severe cases severity Symptom the disease thymoquinone treat Treatment Vaccine α-hederin α-hederin. [DOI] 10.1016/j.phymed.2020.153277 PMC 바로가기 [Article Type] Review
Medicinal Plants in COVID-19: Potential and LimitationsPharmacology Published on 2021-03-242022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome affected Anti-inflammatory Antiviral Azadirachta indica circulating Community complementary complementary therapy Complication coronavirus COVID-19 Cytokine storm demonstrated Efficacy ethnopharmacology Evidence group Herbs identify immunomodulatory effect immunomodulatory effects in silico Intervention investigated limitation lockdowns management media medicinal plants Nigella Sativa novel coronavirus disease pandemic plant positive Post-infection Potential Quality reported Research researcher SARS-CoV-2 selected Treatment Vaccine [DOI] 10.3389/fphar.2021.611408 PMC 바로가기 [Article Type] Pharmacology
In silico identification of compounds from Nigella sativa seed oil as potential inhibitors of SARS-CoV-2 targetsResearch Published on 2021-03-122022-10-28 Journal: Bulletin of the National Research Centre [Category] COVID-19, [키워드] β-bisabolene 3CLpro ACE2 ADP alleviate Angiotensin-converting enzyme binding affinity characterized claimed Compound COVID-19 infection COVID-19 pandemic docking enzyme fatality highest Homo sapiens identify infected individual inhibitors of SARS-CoV-2 molecular Nigella Sativa Patient phosphatase polyprotein protease replicase reported Result RNA binding protein RNA-dependent RNA polymerase RPIA SARS-CoV-2 SARS-CoV-2 receptors selective severity target targets viral infection was performed [DOI] 10.1186/s42269-021-00517-x PMC 바로가기 [Article Type] Research
Propolis, Bee Honey, and Their Components Protect against Coronavirus Disease 2019 (COVID-19): A Review of In Silico, In Vitro, and Clinical Studies프로폴리스, 꿀벌 꿀 및 그 구성 요소는 코로나바이러스 질병 2019(COVID-19)로부터 보호합니다: In Silico, In Vitro 및 임상 연구에 대한 검토Review Published on 2021-02-252022-09-10 Journal: Molecules [Category] MERS, 임상, 치료제, [키워드] ACE-II activities Anti-inflammatory antioxidant Antiviral antiviral drug Antiviral effect Antiviral treatment bee bee honey bee products caffeic acid clinical Combination component Compound coronavirus disease Coronavirus disease 2019 Coronaviruses COVID -19 COVID-19 cytokine Cytokine storm discharge Effect Effects examined exhibited Express fatality flavonoids green Honey hospital hospitalized COVID-19 patient hospitalized COVID-19 patients host cells immune immunomodulatory in silico in vitro inhibit inhibited less Liposome Luteolin main protease molecular docking/biochemical modeling molecular simulations Mortality naringin natural Nigella Sativa non-structural protein non-structural proteins Prophylactic Propolis randomized clinical trials receiving Remdesivir respiratory review rutin SARS-CoV-2 SARS-COV-2 infection Severe acute respiratory syndrome spike glycoprotein standard care Symptom the cytokine storm these compound these compounds Treatment treatment for COVID-19 Treatment outcome Trigger Vero E6 VERO E6 cells Viral viral clearance viral replication viral spike viral-host interaction virulence [DOI] 10.3390/molecules26051232 PMC 바로가기 [Article Type] Review
Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients?Thymoquinone: SARS-CoV2에 감염된 암 환자의 타이 브레이커?Review Published on 2021-02-022022-08-31 Journal: Cells [Category] MERS, 신약개발, 치료제, [키워드] adjuvant Anti-inflammatory anti-SARS-CoV-2 Antibiotics anticancer anticancer drugs antioxidant effect antioxidant effects antipyretics Antiviral antiviral therapies Apoptosis Cancer cancer patient Cancer patients Cancer therapy caused Combination Comorbidity Complication complications coronavirus disease COVID-19 COVID-19 complications COVID-19 infection COVID-19 treatments develop drug Effect Effects General population GRP78 healthcare higher risk Hydroxychloroquine Immunocompromised include Infection ingredient initiated malignancy medications Mild symptom mild symptoms multiple-organ Nigella Sativa Nrf2 pandemic pathophysiology Patient symptoms patients Plasma transfusion RAS reported respiratory SARS-CoV-2 serious complication Severe acute respiratory syndrome Supportive treatments Symptom Symptomatic treatment therapy thymoquinone Treatment Vaccine Viral viral infection virus [DOI] 10.3390/cells10020302 PMC 바로가기 [Article Type] Review
Tutankhamun’s Antimalarial Drug for Covid-19투탕카멘의 코로나19 치료제Article Published on 2021-01-012022-09-11 Journal: Drug research [Category] 신약개발, 치료제, [키워드] antimalarial antimalarial drug Antimalarial drugs Antiviral antiviral activity approved drug approved drugs article cells choice condition contrary coronavirus current died drug drug candidate effort endosomal pH identify Increases infected with SARS-CoV-2 Interaction Laboratory malaria mechanism mechanism of action New coronavirus Nigella Sativa Nigella sativa - outbreak pandemic Patient Pharaoh physicochemical Predictive provide Research SARS-CoV-2 Side effects starting thymoquinone tomb treat Tutankhamun [DOI] 10.1055/a-1274-1264 PMC 바로가기 [Article Type] Article