Determination of rSpike Protein by Specific Antibodies with Screen-Printed Carbon Electrode Modified by Electrodeposited Gold Nanostructures전착된 금 나노구조에 의해 변형된 스크린 인쇄된 탄소 전극이 있는 특정 항체에 의한 rSpike 단백질의 측정Article Published on 2022-08-032022-09-11 Journal: Biosensors [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 albumin antibodies antibody antigen–antibody complex applicability binding Blood bovine bovine serum albumin carbon changed coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cyclic voltammetry (CV) Determination differential pulse voltammetry (DPV) DPV electrochemical immunosensor electrochemical impedance spectroscopy (EIS) electrode electron transfer evaluated exhibit gold gold nanostructures (AuNS) heterogeneous Interaction L-cysteine limit limit of detection nanostructure nonspecific Patient Protein pulse quantification rate constant Research respiratory SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 virus self-assembled monolayer (SAM) serum serum albumin severe acute respiratory syndrome Coronavirus solution Specific specific antibodies specific antibody specificity spike Spike protein spike protein (Spike). Spike proteins surface area was performed was used were assessed [DOI] 10.3390/bios12080593 PMC 바로가기 [Article Type] Article
Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?COVID-19의 장기 발현: 부검을 통해 지금까지 (뿐만 아니라) 무엇을 배웠습니까?Review Published on 2022-08-012022-09-11 Journal: Virchows Archiv [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Acute kidney damage alveolar alveolar damage analytical methods Antithrombotic applicability Autopsies Autopsy cells change characterized clinical Combination conditions COVID-19 COVID-19 pandemic declining diffuse Diffuse alveolar damage direct infection disease Endothelial dysfunction explained immune response International Intussusceptive angiogenesis kidney limitation majority manifestation mechanism mechanisms morphological feature morphological features National nonspecific open organ organ injury organs pathological change pathological changes pathologist pathophysiology question recommendation Research SARS-CoV-2 supported thrombosis tissue tissue tropism tissues Treatment turn variants variants of concern vascular inflammation vasoconstriction [DOI] 10.1007/s00428-022-03319-2 PMC 바로가기 [Article Type] Review
Antibodies to SARS-CoV-2 in patients with primary immunodeficiencies treated with nonspecific immunoglobulins비특이적 면역글로불린으로 치료받은 원발성 면역결핍증 환자의 SARS-CoV-2에 대한 항체Article Published on 2022-08-012022-09-12 Journal: Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] immunodeficiency Immunoglobulin nonspecific Patient SARS-CoV-2 treated [DOI] 10.1111/imm.13495 PMC 바로가기 [Article Type] Article
Post-Acute COVID-19 Syndrome for Anesthesiologists: A Narrative Review and a Pragmatic Approach to Clinical CareReview article Published on 2022-08-012022-10-05 Journal: Journal of cardiothoracic and vascular anesthesia [Category] SARS, 임상, [키워드] acute infection anticoagulation avoidance blocking agent Brain chest pain clinical clinical care Clinical practice Cognitive impairment consequence coronavirus disease Course COVID-19 criterion Critical care determine Dyspnea Evidence fatigue Health healthy higher risk include Infection initial Long COVID lung-protective ventilation medication Mental Mortality Myopathy narrative nonspecific pandemic Patient patients performed Perioperative care perioperative considerations persistence physical Post-acute COVID-19 syndrome post-viral syndrome postoperative Pragmatic preoperative evaluation Pulmonary pathology regimen respiratory complication review Seven syndrome the United State [DOI] 10.1053/j.jvca.2021.09.051 [Article Type] Review article
Coronavirus disease 2019 and the placenta: A literature review코로나바이러스 질병 2019 및 태반: 문헌 검토Review Published on 2022-08-012022-09-11 Journal: Placenta [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 Antigen Basigin canonical cathepsin B Cathepsin B/L caused CD147 CD26 Chain Reaction Clinical pathology coding coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CTL dipeptidyl peptidase Dipeptidyl peptidase-4 DPP4 electron microscopy eligible enzyme evaluate Express expressed Factor fetal furin IFITM1 immunohistochemistry implicated In situ hybridization interferon involved literature review Localization LY6E lymphocyte mechanism Microscopy multiple organ multiple organs nonspecific organ systems Particle Particles Pathogenesis pathogenesis of SARS-CoV-2 pathology permissiveness Placenta placental Placental infection placental pathology polymerase chain polymerase chain reaction Pregnancy pregnancy trimesters profile Proteases Protein Proteins receptor reduce RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptors Serine severe acute respiratory syndrome Coronavirus single-cell analysis the disease TMPRSS2 transmembrane transmembrane protein transmembrane serine protease Vascular viral pathogenesis Viral RNA virus [DOI] 10.1016/j.placenta.2022.07.007 PMC 바로가기 [Article Type] Review
All-Atom Simulations of Human ACE2-Spike Protein RBD Complexes for SARS-CoV-2 and Some of its Variants: Nature of Interactions and Free Energy Diagrams for Dissociation of the Protein ComplexesSARS-CoV-2 및 일부 변이체에 대한 인간 ACE2-스파이크 단백질 RBD 복합체의 전체 원자 시뮬레이션: 단백질 복합체의 해리를 위한 상호작용 및 자유 에너지 다이어그램의 특성Article Published on 2022-07-282022-09-11 Journal: The journal of physical chemistry. B [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 Analysis atomic level average Comparative analysis Diagram dissociation electrostatic electrostatic interaction energy FIVE Free free energy Free energy calculation Free energy calculations Human human Ace2 protein hydrogen Hydrogen bond increase increase in Interaction investigated L452R molecular molecular dynamics mutant N501Y Nature nonspecific pathway positive Protein RBD RBD-ACE2 RBDs Receptor binding domain SARS-CoV-1 SARS-CoV-2 Simulation Spike protein the RBD the spike protein trajectory variant variants variants of SARS-CoV-2 wild type [DOI] 10.1021/acs.jpcb.2c00833 PMC 바로가기 [Article Type] Article
Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into CellsSARS-CoV-2 세포로의 진입을 완전히 차단하려면 Vacuolar-ATPase 및 TMPRSS2의 이중 억제가 필요합니다Article Published on 2022-07-192022-09-11 Journal: Antimicrobial Agents and Chemotherapy [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] absence Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ATPase bafilomycin block viral entry camostat cathepsin inhibitor Cathepsins Cell cellular Compound coronavirus E64d Efficacy endosomal pH endosomal protease endosome expressing highlight host cell host protease host proteases Hydroxychloroquine identify implicated Infection inhibit inhibiting inhibition inhibitor inhibitors Intervention life cycle Macrolide maturation mechanisms membrane fusion molecules Neutralizing nonspecific Pathways pharmacological agent Prevent protease Protein proteolytic activation provide pseudotyped rationale S protein SARS SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection Serine serine 2 serine proteases severe acute respiratory syndrome Coronavirus synergy the S protein these compound these compounds TMPRSS2 TMPRSS2 inhibitor TMPRSS2-expressing cells toxicities Toxicity transmembrane V-ATPase viral entry viral spike virus [DOI] 10.1128/aac.00439-22 PMC 바로가기 [Article Type] Article
Evaluation of Two Broadly Used Commercial Methods for Detection of Respiratory Viruses with a Recently Added New Target for Detection of SARS-CoV-2SARS-CoV-2 검출을 위해 최근에 추가된 새로운 표적으로 호흡기 바이러스 검출을 위해 널리 사용되는 두 가지 상용 방법 평가Article Published on 2022-07-132022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 agreement ARI AusDiagnostics AusDiagnostics assay automated caused clinical symptom Clinical symptoms coronavirus COVID-19 COVID-19 patient COVID-19 patients detect detection Essential Inc. Mascot medium molecular Molecular assay New nonspecific option other respiratory virus Other respiratory viruses reference method respiratory respiratory tract infection respiratory virus respiratory viruses SARS-CoV-2 Seven severe acute respiratory syndrome Coronavirus specificity target validation [DOI] 10.3390/v14071530 PMC 바로가기 [Article Type] Article
Repurposing drugs as COVID-19 therapies: A toxicity evaluationCOVID-19 치료제로 약물 용도 변경: 독성 평가Review Published on 2022-07-012022-09-11 Journal: Drug discovery today [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] analyzed anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity approved autophagy blockers chemical structures clinical trials contributed correlated COVID-19 CPE Cytopathic effect cytotoxicity database drug drug candidate drug candidates Drug interactions Drug repurposing Efficiency enrolled ether hERG High-throughput screening highlight house identify In vitro assay induce nonspecific pandemic Phospholipidosis profile repurposing SARS-CoV-2 Severe acute respiratory syndrome significantly Structure Toxicity [DOI] 10.1016/j.drudis.2022.04.001 PMC 바로가기 [Article Type] Review
Acute Disseminated Encephalomyelitis After SARS-CoV-2 VaccinationSARS-CoV-2 백신 접종 후 급성 파종성 뇌척수염Case Reports Published on 2022-06-192022-09-12 Journal: The American journal of case reports [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Acute disseminated encephalomyelitis acute respiratory syndrome addition Anxiety Brain Central nervous system cerebrospinal fluid coronavirus Course COVID-19 COVID-19 vaccination disorder dose dysfunction Electroencephalography elevated Encephalomyelitis epileptiform etiology highlight hospital hypertension illnesses Infection initial initial treatment Intravenous immunoglobulin intubation leukoencephalopathy management Methylprednisolone MRI multiple sclerosis neurologic nonspecific Novel coronavirus Pfizer physical exam Protein receiving SARS-CoV-2 Seizure steroid Steroids treated Treatment vaccination Vaccinations Vaccine was obtained weakness [DOI] 10.12659/AJCR.936574 PMC 바로가기 [Article Type] Case Reports