Ultrasensitive monitoring of SARS-CoV-2-specific antibody responses based on a digital approach reveals one week of IgG seroconversionArticle Published on 2022-12-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] addition antibodies Antibody Response approach AUC collected COVID-19 COVID-19 patient diagnostic diagnostics Donor Extreme early-stage seroconversion faster flow cytometry healthy IgG IgG and IgM IgG/IgM antibodies IgM immunoassay immunoassays immunological inactivated nucleic acid nucleic acids other diseases pathogen-specific Patient peptide platform probe Protein RBD reveal Rhesus monkeys SARS-CoV-2 S2 sensitivity Seroconversion seroconversion time Simoa tested Ultrasensitive digital detection. vaccination virus wild-type [DOI] 10.1016/j.bios.2022.114710 PMC 바로가기
Current trends in COVID-19 diagnosis and its new variants in physiological fluids: Surface antigens, antibodies, nucleic acids, and RNA sequencingReview article Published on 2022-12-012022-10-05 Journal: TrAC Trends in Analytical Chemistry [Category] 바이오마커, 변종, 진단, 치료기술, [키워드] addressed antibodies antibody Antigen antigens Beta Biomarker biosensors Blood body fluid circulation clustered regularly interspaced short palindromic repeats COVID-19 COVID-19 diagnosis COVID-19 virus diagnosis CRISPR Critical current Delta Detection sensitivity diagnostic early stage ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Gamma Infection isothermal amplification lateral flow immunoassay LFIA limit Loop-mediated isothermal amplification microarray analysis Microarray assays Mutation nucleic acid nucleic acids omicron outbreak overcome palindromic repeat physiological provide Rapid reduce reverse transcriptase-polymerase chain reaction reverse transcription RNA sequencing RT-LAMP RT-PCR Saliva SARS-CoV-2 Semen specificity Spread surface Urine variant variants virus viruses [DOI] 10.1016/j.trac.2022.116750 [Article Type] Review article
Pandemic driven innovation: A pilot evaluation of an alternative respiratory pathogen collection deviceArticle Published on 2022-11-012022-11-16 Journal: The American journal of emergency medicine [Category] SARS, 유전자 메커니즘, [키워드] absence All participant amplification communicable disease COVID-19 demonstrated determine diagnostic enrolled evaluated faster favor feedback fused gold standard identify inhibitor Innovation Interpretation invasive mechanism nasopharyngeal Nasopharyngeal swab nucleic acids participant Patient PCR PCR cycle PCR testing pilot study polymerase chain positive producing real-time reverse transcriptase receiving respiratory respiratory pathogen respiratory virus Result resulting RNase P RNAseP RT-qPCR Self-collection respiratory pathogen device. specimen study participant TaqPath tested threshold [DOI] 10.1016/j.ajem.2022.08.047 PMC 바로가기
De novo selected hACE2 mimics that integrate hotspot peptides with aptameric scaffolds for binding tolerance of SARS-CoV-2 variantsArticle Published on 2022-10-282022-11-15 Journal: Science Advances [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] acute respiratory syndrome Antiviral binding coronavirus Critical de novo evade exhibited hACE2 host cell hotspot human Angiotensin-converting enzyme immune in vitro Interaction Ligand Neutralizing nucleic acids Occurrence omicron peptide Prophylaxis random reagents Receptor binding receptors recruit SARS-CoV-2 SARS-CoV-2 variant selected Tolerance Vaccine variant variants viral variant virus [DOI] 10.1126/sciadv.abq6207 PMC 바로가기
Forty Years of Molecular Diagnostics for Infectious DiseasesArticle Published on 2022-10-192022-11-15 Journal: Journal of Clinical Microbiology [Category] 유전자 메커니즘, 진단, 치료기술, [키워드] amplification assumed Care coronavirus disease COVID-19 detect diagnostic diagnostic molecular microbiology diagnostics DNA DNA sequencing elapsed Factors Health in vitro Infectious disease Intersection knowledge Magnetic beads microbial molecular nucleic acid nucleic acids nucleotide nucleotide array pandemic pathophysiologic PCR Perspective point of care progression quantification Quantitative real-time quantitative PCR Sequencing syndromic panel. turn Year [DOI] 10.1128/jcm.02446-21 PMC 바로가기
Performance of nasopharyngeal swab and saliva in detecting Delta and Omicron SARS-CoV-2 variantsDelta 및 Omicron SARS-CoV-2 변이체 검출 시 비인두 면봉 및 타액의 성능Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analyzed Chain Reaction characterized conducted coronavirus cough COVID-19 Delta diagnostic Dyspnea epidemic wave epidemic waves expressed highest increase in Infection Laboratory log molecular nasopharyngeal Nasopharyngeal swab no significant difference not significant NP swab NP swabs NPs nucleic acids omicron participant Participants Patient performance polymerase chain polymerase chain reaction processing prospective cohort study real-time RT-PCR reported required respiratory rhinorrhea RNA Saliva saliva samples Sample SARS-CoV-2 SARS-CoV-2 diagnostics SARS-CoV-2 epidemic SARS-CoV-2 variant significant difference sore sore throat specimen specimen collection statistically Symptom Symptoms thawing the mean transported Viral Viral load [DOI] 10.1002/jmv.27898 PMC 바로가기 [Article Type] Article
AuNP-based biosensors for the diagnosis of pathogenic human coronaviruses: COVID-19 pandemic developmentsArticle Published on 2022-10-012022-11-15 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Antigen Asymptomatic carrier AuNP AuNPs biofluid Biomarker CoV COVID-19 epidemic COVID-19 pandemic CoVs CRISPR Diagnosis Diagnostic method Early detection example gold helping higher risk highlight highly pathogenic CoV Human human coronavirus human coronaviruses identify Laboratory MERS-CoV nanobiosensors nucleic acids optical outbreak pathogenic Pathogenic. platform point-of-care Probability Protein provided RT-PCR SARS-CoV-1 SARS-CoV-2 Spread the disease the SARS-CoV-2 Transmission treatment intervention virus viruses [DOI] 10.1007/s00216-022-04193-2 PMC 바로가기
Non-enzymatic signal amplification-powered point-of-care SERS sensor for rapid and ultra-sensitive assay of SARS-CoV-2 RNASARS-CoV-2 RNA의 신속하고 초민감한 분석을 위한 비효소 신호 증폭 기반 현장 진료 SERS 센서Article Published on 2022-09-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplification carried ChIP clinical samples Combination COVID-19 diagnostic DNA Early detection expected generate Nuclease nucleic acids other respiratory virus Other respiratory viruses point-of-care Prevention and control probe Raman spectroscopy Recognition respiratory viruses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA sensitivity SERS silver target Target recycling signal amplification. ultra-sensitive assay viral nucleic acids virus infection [DOI] 10.1016/j.bios.2022.114379 PMC 바로가기 [Article Type] Article
Association of extracellular vesicle inflammatory proteins and mortality세포외 소포 염증 단백질과 사망률의 연관성Article Published on 2022-08-182022-09-11 Journal: Scientific Reports [Category] 바이오마커, [키워드] age Biomarker CCL23 CDCP1 circulating Cohort Concentration COVID-19 pandemic CSF-1 CXCL9 Deceased Decline died disease DNA Ethnic groups EVs Extracellular Extracellular vesicles functional GDNF identify increased mortality individual inflammatory protein inflammatory proteins intercellular Life expectancy lipids marker MCP-1 mitochondrial mitochondrial DNA Mortality no significant difference no significant differences nucleic acids plasma Potential biomarker potential biomarkers Proteins Racial risk Sex significantly STAMBP the United State United States Vesicle [DOI] 10.1038/s41598-022-17944-z PMC 바로가기 [Article Type] Article
Maternal vaccination as an additional approach to improve the protection of the nursling: Anti-infective properties of breast milkArticle Published on 2022-08-102022-11-15 Journal: Clinics [Category] 진단, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 vaccines antibody Antibody Response approach B lymphocyte bacterial antigen Bioactive factors Breast breast milk Breastfeeding chemokines complement component cytokine elevated Factors fatty acids function Growth factors hormone Human IgA IgA antibodies IgA antibody IgG antibody IMPROVE inactivated induce lactation lactoferrin leukocyte mammary Maternal maternal immunization MicroRNAs nucleic acids oligosaccharides pandemic passive immunity performed Placenta Plasma cell plethora polysaccharide Pregnancy produced Proteins respiratory infections respiratory tracts secretion secretory secretory IgA Secretory IgA antibodies. Specific specific antibody unique vaccination Vaccine Vaccines virus virus-neutralizing viruses [DOI] 10.1016/j.clinsp.2022.100093 PMC 바로가기