Marginal BH4 deficiencies, iNOS, and self-perpetuating oxidative stress in post-acute sequelae of Covid-19Research article Published on 2022-06-012022-10-05 Journal: Medical Hypotheses [Category] 변종, 유전자 메커니즘, [키워드] AGMO approach Clinical treatment deficiencies deficiency exhibited Ferroptosis GCH1 GCH1 mutations GTP heterozygous homozygous mutation hyperinflammatory state impair Inflammatory initial innate immune system involved less manuscript Marginal Marginally deficient BH4 metabolic processe Mutation nitric oxide organ systems organs oxidative stress Oxide PASC Post-acute sequelae of COVID-19 (PASC) resulting SARS-CoV-2 symptomatic Synthase tetrahydrobiopterin the patient Treatment Uncoupling iNOS [DOI] 10.1016/j.mehy.2022.110842 [Article Type] Research article
[Optimal oxygen administration-new evidence from treating COVID-19?][최적의 산소투여-코로나19 치료의 새로운 증거?]Review Published on 2022-06-012022-09-11 Journal: Medizinische Klinik, Intensivmedizin Und Notfallme [Category] 치료제, [키워드] activate Cell cells changes in Clinical practice compensatory mechanism compensatory mechanisms coronavirus disease Coronavirus disease 2019 COVID-19 disorders English environmental factors Evidence functional Gang highlight human body human cells hypoxia Injury integrity invasive knowledge Lactates mechanism organ damage organ systems oxygen Oxygen consumption oxygen levels oxygen saturation Oxygenation pandemic pathophysiology physiological mechanism Physiology Prevent remain unchanged risk Side effect survival target therapeutic strategy therapy [DOI] 10.1007/s00063-022-00914-8 PMC 바로가기 [Article Type] Review
Symptom burden correlates to impairment of diffusion capacity and exercise intolerance in long COVID patients Research Published on 2022-05-252022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 6-MWT acute infection affected Analysis average capillary blood Cohort correlated correlation COVID COVID patient Covid patients defined demonstrated diffusion capacity disease severity examined Follow-up functional Hospitalization impairment initial intensive care lung Mental mental health organ damage organ systems parameters pathological change Patient physical positive correlation quartile quartiles questionnaire reduced resulting significantly more Symptom symptom burden symptom severity symptomatic the SARS-CoV-2 virus Tolerance women [DOI] 10.1038/s41598-022-12839-5 [Article Type] Research
The Sexual Long COVID (SLC): Erectile Dysfunction as a Biomarker of Systemic Complications for COVID-19 Long HaulersSLC(Sexual Long COVID): COVID-19 장거리 운송인을 위한 전신 합병증의 바이오마커로서의 발기부전Review Published on 2022-04-012022-09-11 Journal: Sexual medicine reviews [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] addressed Affect affected Anxiety Biomarker cardiovascular Cardiovascular health cardiovascular system caused clinical manifestation clinical manifestations Complication complications complications of COVID-19 Comprehensive conditions contributing to coronavirus Coverage COVID COVID-19 Depression develop diabetes disease dysfunction Dyspnea Endocrine Endothelial dysfunction Epidemiology Erectile dysfunction event fatigue feature fibrosis Follow-up Health human body hypogonadism impair in some life life-threatening Long Long COVID long term management Manifestations mechanisms myocarditis Neuropsychiatric organ systems pathophysiology Patient physical plethora prevalent pulmonary fibrosis Quality of life reported Research respiratory severity sexual subset systemic the disease the SARS-CoV-2 Thyroid thyroid dysfunction Topic worsening [DOI] 10.1016/j.sxmr.2021.11.001 PMC 바로가기 [Article Type] Review
Exerkines in health, resilience and disease Reviews Published on 2022-03-182022-10-05 Journal: Nature Reviews Endocrinology [Category] 바이오마커, 유전자 메커니즘, [키워드] adipose autocrine benefit cardiovascular disease Cell defined disease Effect Endocrine ENhance Factors Health healthy IL-6 immune liver molecular mechanism neurological Neuron obesity organ systems organs paracrine Pathways Release released Research Resilience review Skeletal muscle tissue Treatment type 2 diabete underlie [DOI] 10.1038/s41574-022-00641-2 [Article Type] Reviews
COVID-19-specific metabolic imprint yields insights into multiorgan system perturbationsCOVID-19 관련 대사 흔적은 다기관 시스템 섭동에 대한 통찰력을 제공합니다Article Published on 2022-03-012022-09-11 Journal: European Journal of Immunology [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Affect aligned alteration capture cellular circulating metabolome Comorbidities Comorbidity confounding factor Corona Coronavirus-2 COVID-19 COVID-19 severity damage defined disease driven by hospitalized COVID-19 patient immune activation immunological immunology indicated Inflammation integration metabolite metabolome metabolomics molecular multi Multi-omics Multiorgan multiple pathway multiple pathways network Neuroinflammation neurological organ damage organ systems performed Perturbation perturbations proteomic question recent resource respiratory SARS-CoV-2 Seroconversion severe acute respiratory syndrome Coronavirus severe COVID-19 patients severity switch trajectory unique [DOI] 10.1002/eji.202149626 PMC 바로가기 [Article Type] Article
Circadian rhythm disruption in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for the post-acute sequelae of COVID-19Research article Published on 2022-03-012022-10-05 Journal: Brain, Behavior, & Immunity - Health [Category] 바이오마커, [키워드] activity autonomic Biomarker Brain cause caused cells changes in characterized chronic fatigue syndrome circadian rhythm cognitive coronavirus COVID-19 COVID-19 pandemic cytokine Depression disorder disrupting dysfunction Evidence examined fatigue growth factor immune implication Inconclusive increasingly Infection Inflammatory response Insomnia Major methodological molecular myalgic encephalomyelitis Older organ systems outbreak over overlap pandemic PASC Perspective physiological problem problems progressed reported Research SARS-CoV2 SARS-like coronavirus Signaling Sleep Symptoms temperature therapeutic interventions transforming growth factor beta viral infections while [DOI] 10.1016/j.bbih.2022.100412 [Article Type] Research article
Arrhythmias in the COVID-19 patientResearch article Published on 2022-02-012022-10-05 Journal: Heart Rhythm O2 [Category] 변종, [키워드] acute respiratory syndrome arrhythmia Arrhythmias Atrial fibrillation Atrioventricular block cardiovascular complications Complication coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patient described disease globe highlight Infection management manifestation organ systems pandemic patient population patients with COVID-19 Respiratory illness SARS-CoV-2 the disease ventricular ventricular tachycardia Ventricular tachycardia storm [DOI] 10.1016/j.hroo.2022.01.002 [Article Type] Research article
A Peek into Pandora’s Box: COVID-19 and NeurodegenerationReview Published on 2022-01-302022-10-28 Journal: Brain Sciences [Category] COVID-19, [키워드] accelerate ACE2 Activation acute respiratory syndrome angiotensin-converting enzyme 2 association Biomarker Brain Central nervous system changes CNS Comorbidity coronavirus COVID-19 current disease disease severity distress Effects gastrointestinal system hypoxia indirect effect individual induce mechanism Mitochondria molecular biology technique neurodegeneration neurodegenerative Neuron organ systems oxidative stress Proinflammatory cytokine provide pulmonary complications receptor renal reported SARS-CoV-2 SARS-COV-2 infection surviving patients susceptibility susceptible therapeutic Therapeutics Vaccine development Variability variant virus virus attack Wuhan, China [DOI] 10.3390/brainsci12020190 PMC 바로가기 [Article Type] Review
The Oral Complications of COVID-19Molecular Biosciences Published on 2022-01-032022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] acute respiratory syndrome Ageusia clinical guideline Complication complications concept COVID-19 COVID-19 patient cured Diagnosis Diseases Health Impact IMPROVE Infectious disease mechanism Novel coronavirus oral organ systems Pathogenesis Patient Perspective Pneumonia Prevent problem Quality of life recommendation recovery rehabilitation reported shown stomatology susceptibility Treatment Vaccines [DOI] 10.3389/fmolb.2021.803785 PMC 바로가기 [Article Type] Molecular Biosciences