Single-cell and transcriptomic analyses reveal the influence of diabetes on ovarian cancerResearch Published on 2024-01-022024-09-05 Journal: BMC Genomics [Category] update2024, [키워드] Diabetes Mellitus Immunotherapy Monocyte marker genes ovarian cancer Single-cell RNA sequencing [DOI] 10.1186/s12864-023-09893-2 PMC 바로가기 [Article Type] Research
Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim resultsarticle Published on 2023-07-272024-09-05 Journal: Nature medicine [Category] update2024, [키워드] Cancer immunotherapy Immunotherapy mesothelioma ovarian cancer Phase I trials [DOI] 10.1038/s41591-023-02452-y PMC 바로가기 [Article Type] article
“It doesn’t really apply to what I’m going through”: A Mixed-Methods Study of Barriers to Palliative Care among Patients with Advanced Ovarian CancerArticle Published on 2023-07-092024-09-05 Journal: Supportive Care in Cancer [Category] update2024, [키워드] Advanced cancer Mixed methods ovarian cancer Palliative care Social ecological model supportive care [DOI] 10.1007/s00520-023-07832-1 PMC 바로가기 [Article Type] Article
A case of niraparib PARP-Inhibitor induced Sweet Syndrome in gynecologic cancerCase Report Published on 2023-03-152024-09-04 Journal: Gynecologic Oncology Reports [Category] 대상포진, [키워드] adverse effects Niraparib ovarian cancer PARPi Sweet syndrome [DOI] 10.1016/j.gore.2023.101162 PMC 바로가기 [Article Type] Case Report
The Impact of COVID-19 Infection During the Postoperative Period After Surgery for Ovarian CancerArticle Published on 2022-05-012023-07-09 Journal: In vivo (Athens, Greece) [Category] COVID19(2023년), [키워드] COVID-19 pandemic debulking surgery ovarian cancer [DOI] 10.21873/invivo.12835 PMC 바로가기
Preclinical In Silico Evidence Indicates the Pharmacological Targets and Mechanisms of Mogroside V in Patients With Ovarian Cancer and Coronavirus Disease 20192019년 난소암 및 코로나바이러스 질환 환자에서 모그로사이드 V의 약리학적 표적 및 메커니즘을 나타내는 전임상 인 실리코 증거Article Published on 2022-04-062022-09-11 Journal: Frontiers in Endocrinology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anticancer biological processe China clinical clinical observations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19-related death docking drug target Effects endothelial enrichment analysis growth factor Hsp90 HSP90AA1 IL2 indicated ingredient Injury mechanism medication Mitigation Mogroside mogroside V molecular docking network pharmacology observation ovarian ovarian cancer pathway Pathways Patient Preclinical preclinical report PRKCA PRKCB reduce remedial targets. reported SARS-CoV-2 Siraitia STAT3 suggested target target protein targets therapeutic therapeutic agent therapeutic efficacy TLR7 TLR9 Transmission Vaccine variant Vascular VEGFA with COVID-19 [DOI] 10.3389/fendo.2022.845404 PMC 바로가기 [Article Type] Article
Virtual Screening of Natural Chemical Databases to Search for Potential ACE2 InhibitorsArticle Published on 2022-03-072022-10-30 Journal: Molecules [Category] COVID-19, [키워드] ACE2 acute lung injury acute respiratory syndrome ADME Angiotensin-converting enzyme binding affinity binding mode calculated Chemical Compound conditions coronavirus coronavirus disease COVID-19 database diabetes disease Diseases Drug discovery drug target drug-likeness evaluate function Glide Health host cell host receptor inhibition activity inhibitor inhibitors Interaction Ligand modulation molecular Molecular dynamics simulation multifunctional protein natural natural products outbreak ovarian cancer performed Potential predicted Prevent Protein RAS Receptor binding domain Result S-protein SARS-CoV-2 Screening TargetMol the SARS-CoV-2 Virtual screening virus [DOI] 10.3390/molecules27051740 PMC 바로가기 [Article Type] Article
Activating a collaborative innate-adaptive immune response to control metastasisArticle Published on 2022-02-162024-09-04 Journal: Cancer cell [Category] 대상포진, [키워드] anti-tumor immune response Breast cancer Cytotoxic T cells IFNγ metastasis treatment MPLA ovarian cancer tumor-associated macrophages [DOI] 10.1016/j.ccell.2021.08.005 PMC 바로가기 [Article Type] Article
Randomised phase II trial of weekly ixabepilone ± biweekly bevacizumab for platinum-resistant or refractory ovarian/fallopian tube/primary peritoneal cancer Research Published on 2022-02-112022-10-05 Journal: British Journal of Cancer [Category] 바이오마커, [키워드] 95%CI bevacizumab Biomarker Cancer clinical Combination effective expression monotherapy ovarian cancer participant Patient predict Predictive primary endpoint randomised receive regimen Result RP2 Secondary endpoints significantly stratified subgroup analysis Trial Trial registration TUBB3 [DOI] 10.1038/s41416-022-01717-6 [Article Type] Research
CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapyArticle Published on 2022-02-072022-10-04 Journal: NPJ Systems Biology and Applications [Category] 바이오마커, [키워드] ACTBL2 Biomarker Biomarkers Cancer candidate Characteristics Combination Computational biology and bioinformatics CTCF CTCFL cytoplasmic membrane de novo Diagnosis driving effective enrichment analysis evaluate expressed females function HGSC High-grade Improving in vitro model involved ITGB3 ITGB6 lack malignancy MALT1 molecular ovarian ovarian cancer Pathomechanism pathway PCDH7 predict prognostic Prognostic marker progression regulate Regulatory resulting survival target target gene targeted therapy targets therapeutic potential therapy tissue transcriptional transcriptional change Treatment VEGFA [DOI] 10.1038/s41540-022-00214-z PMC 바로가기 [Article Type] Article