Use of Sewage Surveillance for COVID-19: A Large-Scale Evidence-Based Program in Hong KongCOVID-19에 대한 하수 감시의 사용: 홍콩의 대규모 증거 기반 프로그램Article Published on 2022-05-012022-09-11 Journal: Environmental health perspectives [Category] COVID19(2023년), SARS, 치료기술, [키워드] analyzed applied approach circulation collected Community conducted convalescent patient COVID-19 COVID-19 transmission detect epidemiological data Hong Kong implementation management Negative predictive value Patient patient groups patients positive Positive predictive value Predictive value Program provided public health Public health interventions SARS-CoV-2 detection SARS-CoV-2 virus sensitivity sewage silent specificity Surveillance tested viral signal [DOI] 10.1289/EHP9966 PMC 바로가기 [Article Type] Article
Circulating microRNA profiling is altered in the acute respiratory distress syndrome related to SARS-CoV-2 infection Research Published on 2022-04-282022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute inflammatory response acute respiratory distress analyzed ARDS cellular COVID-19 COVID-19 patients Cytokine storm Cytokine storm syndrome dataset differentially expressed miRNA enriched pathway fat cell fold Gene Expression hallmark immune immune dysregulation in silico analysis independent Infection Inflammatory response Inflammatory responses intensive care involved mechanical ventilation microRNA miRNA miRNAs parameter pathway enrichment Patient patient groups physiological Prognosis qPCR receptor protein Regulation resulting SARS-COV-2 infection Sequencing significantly Symptom syndrome transmembrane was performed with COVID-19 [DOI] 10.1038/s41598-022-10738-3 [Article Type] Research
COVID-19 in Elderly, Immunocompromised or Diabetic Patients-From Immune Monitoring to Clinical Management in the Hospital고령자, 면역저하, 당뇨병 환자의 코로나19-면역 모니터링부터 병원 내 임상 관리까지Article Published on 2022-04-012022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory illness acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 cellular Cellular immune response cellular immune responses clinical Clinical management Cohort cohorts Comorbidities complicate Complication coronavirus correlated Course COVID-19 Ct value cycle threshold detectable develop diabete diabetes Diabetes Mellitus Diabetic diabetic patient elderly elderly patients Factor group Healthcare system hospital Hospitalization Hospitalized humoral Humoral and cellular immune responses humoral immune response humoral immune responses immune response immune responses Immunocompromised Immunocompromised patient Immunocompromised patients increased risk Isolation majority monitoring MOST Nasopharyngeal swab nasopharyngeal swabs Nosocomial infections novel nursing homes pandemic Patient patient cohort patient groups patients patients with diabete positive producing reduced replication-competent virus representing Respiratory illness respond robust SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 RNA detection sensitivity severe acute respiratory syndrome Coronavirus symptomatic symptomatic COVID-19 triggered viral culture viral loads virus [DOI] 10.3390/v14040746 PMC 바로가기 [Article Type] Article
COVID-19 Vaccines: An Overview of Different PlatformsReview Published on 2022-02-122022-10-28 Journal: Bioengineering [Category] COVID-19, [키워드] approach approved boost clinical development Clinical efficacy conducted Course COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines determine DNA vaccines effective Effectiveness Efficacy evaluate immune IMPROVE Inactivated Vaccines literature review mRNA Mutation new SARS-CoV-2 patient groups peptides platform prevention Research RNA RNA vaccine shown single vaccination stability subunit vaccination Vaccine Vaccine development variant vector virus [DOI] 10.3390/bioengineering9020072 PMC 바로가기 [Article Type] Review
Long-term efficacy and safety of SARS-CoV-2 vaccination in patients with chronic kidney disease, on dialysis or after kidney transplantation: a national prospective observational cohort studyStudy Protocol Published on 2022-02-052022-10-28 Journal: BMC Nephrology [Category] COVID-19, [키워드] adverse event adverse events Analysis antibodies antibody Antibody Response assessment Breakthrough infection Characteristics Chronic kidney disease CKD contribute control group Course COVID-19 COVID-19 in patient current dialysis effective Efficacy Efficacy and safety Endpoint endpoints Follow-up follow-up period Guidance immune response Impact incidence incidence of COVID-19 kidney kidney transplant recipients Kidney transplantation knowledge lack less methodology monitoring morbidity and mortality Mortality National outcome Patient patient group patient groups patients predict primary endpoint prospective observational cohort questionnaire recent Registered Result Safety SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine secondary severe COVID-19 Stage Study design Study protocol subgroup subject supplementary material therapy Trial vaccination Vaccine virus [DOI] 10.1186/s12882-022-02680-3 PMC 바로가기 [Article Type] Study Protocol
Implications of SARS-CoV-2 infection on the clinical, hematological, and inflammatory parameters in COVID-19 patients: A retrospective cross-sectional studySARS-CoV-2 감염이 COVID-19 환자의 임상, 혈액학 및 염증 매개변수에 미치는 영향: 후향적 횡단면 연구Article Published on 2022-02-012022-09-11 Journal: Journal of infection and public health [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory syndrome Admission age Analysis AST Atypical Atypical pneumonia bacterial and fungal infections baseline data biological markers Biomarker caused characteristic characterized clinical clinical laboratory Clinical parameters Clinical predictors Coagulation colds Comorbidities coronavirus COVID COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity creatine creatinine cross-sectional study CRP D-dimer determine examined ferritin FIVE fungal infections group groups help hematologic hematological hematological parameters highest illnesses Inflammatory biomarker inflammatory biomarkers Inflammatory marker inflammatory markers inflammatory parameter intensive care laboratory data laboratory parameter Laboratory parameters liver liver biomarkers medications Mild Most patients not differ operator Organ failure pandemic parameter Patient patient groups patients Pneumonia predictor procalcitonin receiver Receiver operator characteristic regulated Regulation renal function respiratory respiratory distress Retrospective cross-sectional study ROC ROC analysis SARS CoV SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection secondary bacterial severe acute respiratory syndrome virus severity severity of COVID-19 Sex significant difference significant differences significantly the disease the patient threshold thrombosis Validity virus was used WBC [DOI] 10.1016/j.jiph.2021.12.013 PMC 바로가기 [Article Type] Article
Role of immune mediators in predicting hospitalization of SARS-CoV-2 positive patientsSARS-CoV-2 양성 환자의 입원 예측에서 면역 매개체의 역할Article Published on 2022-02-012022-09-11 Journal: Cytokine [Category] COVID19(2023년), SARS, 바이오마커, [키워드] chemokines Clinical outcome clinical utility Cohort Concentration correlation COVID-19 COVID-19 severity Cytokines determine determined by disease severity group Hospital stay Hospitalization hospitalized patient IL-18 IL-6 immune Immune mediator MCP-1 mediator moderate Multiplex assay notable pathophysiology patient groups PCR positive positive patient Predictive predictor profile receptor role SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 patients SARS-CoV-2 PCR SARS-CoV-2 positive patient severity sIL-2Rα Spearman suggested survival tested was used [DOI] 10.1016/j.cyto.2021.155790 PMC 바로가기 [Article Type] Article
Endocan as a potential marker in diagnosis and predicting disease severity in COVID-19 patients: a promising biomarker for patients with false-negative RT-PCRCOVID-19 환자의 진단 및 질병 중증도 예측의 잠재적 마커로서의 Endocan: 위음성 RT-PCR 환자를 위한 유망한 바이오마커Original Article Published on 2022-01-242022-09-10 Journal: Upsala Journal of Medical Sciences [Category] SARS, 바이오마커, [키워드] assistant Biomarker Blood blood test can be used Clinical severity control group correlation COVID-19 COVID-19 case COVID-19 cases COVID-19 disease COVID-19 infection COVID-19 patient COVID-19 patients cut-off value determine Diagnosis diagnostic value disease severity endocan enrolled false false-negative healthy control healthy individual healthy individuals Inflammatory biomarker Laboratory laboratory findings marker no significant difference Patient patient group patient groups patients PCR tests polymerase positive correlation positive RT-PCR radiological Result reverse transcription reverse transcription polymerase change reaction RT-PCR RT-PCR test SARS-CoV-2 sensitivity serum significant difference significantly specificity the disease [DOI] 10.48101/ujms.v127.8211 PMC 바로가기 [Article Type] Original Article
What’s happening where when SARS-CoV-2 infects: are TLR7 and MAFB sufficient to explain patient vulnerability?Review Published on 2022-01-222022-10-30 Journal: Immunity & Ageing : I & A [Category] COVID-19, [키워드] age Characteristics COVID-19 COVID-19 pandemic cytokine response demographic group dendritic cell explain Infection interferon Macrophage macrophages MAFB Male sex miR-146a obese obesity pathway Patient patient groups plasmacytoid dendritic cells pro-inflammatory cytokine SARS-CoV-2 sensitivity severe COVID-19 disease Severe infection skewed TLR-tolerance TLR7 vulnerable patients [DOI] 10.1186/s12979-022-00262-3 PMC 바로가기 [Article Type] Review
SARS-CoV2-specific Humoral and T-cell Immune Response After Second Vaccination in Liver Cirrhosis and Transplant Patients간경변 및 이식 환자에서 2차 예방접종 후 SARS-CoV 2 특이 체액 및 T 세포 면역 반응Article Published on 2022-01-012022-09-12 Journal: Clinical gastroenterology and hepatology : the off [Category] SARS, 진단, [키워드] 95% CI 95% confidence interval acute respiratory syndrome age anti-S anti-SARS-CoV-2 anti-SARS-CoV-2 titer Arterial hypertension booster vaccinations cirrhosis Cohort Control controls coronavirus develop DiaSorin Effect Elecsy Euroimmun healthy control Heterologous humoral identify immune response immunoassay Immunosuppression immunosuppressive information inhibitor less LIAISON liver Liver cirrhosis liver transplant recipients Logistic regression analysis monotherapy Odds ratio Patient patient groups predictor prospective cohort study RBD recipient recipients reduction regimen Research response Roche routine SARS-CoV-2 SARS-CoV-2 vaccination second second vaccination Seroconversion Serological testing spike-protein spike-specific T-cell response T-cell T-cell Response Transplant trimer vaccination was performed [DOI] 10.1016/j.cgh.2021.09.003 PMC 바로가기 [Article Type] Article