Evidence for the evolutionary steps leading to mecA -mediated β-lactam resistance in staphylococci
포도상구균에서 mecA 매개 β-락탐 내성으로 이어지는 진화 단계에 대한 증거
Research Article
[키워드] accumulation
acquisition
adaptation
Amino acid
Analysis
antibiotic
Antibiotic resistance
Antibiotics
Author
Bacteria
Bacterial
Bayesian analysis
binding
binding domain
cell wall
cell wall synthesis
changes in
chromosome
Community
core genome
development
domain
driving
epidemiologically
Evolution
exposure to
food additives
gene encoding
Genetic
genetic background
genomes
highlight
homologue
identify
involved
isolates
livestock
mechanism
mechanisms
methicillin
methicillin-resistant Staphylococcus aureus
Mortality
MRSA
mutation rate
Mutation rates
non-binding
nucleotide
occur
occurred
oxacillin
Pandemics
PBP
penicillin
phenotype
Phylogenetic analysis
precursor
predicted
profiles
promoter
promoters
Protein
representing
resistance gene
resource
responsible
S . aureus
SCC
selective
sequence
sequence alignments
sequenced genome
single-nucleotide polymorphism
SNP
species
Spread
Staphylococcus
Staphylococcus aureus
strain
Substitution
substitutions
susceptibility
variety
was performed
[DOI] 10.1371/journal.pgen.1006674 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1006674 PMC 바로가기 [Article Type] Research Article