Development of computer-aided model to differentiate COVID-19 from pulmonary edema in lung CT scan: EDECOVID-net폐 CT 스캔에서 코로나19와 폐부종을 구별하는 컴퓨터 지원 모델 개발: EDECOVID-netArticle Published on 2022-02-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy acetazolamide addition Administered Algorithm automatically benefit breathing carbon dioxide Computer-aided detection system (CADs) Consequences COVID-19 COVID-19 patient COVID-19 patients COVID-19 symptom COVID-19 symptoms CT images detection system development diagnosing early stages edema effort Features Hypotension knowledge Lung CT lung CT scan Lung CT scans machine machine learning matching mathematical Patient Perfusion Prevent pulmonary Pulmonary edema risk spread of COVID-19 systemic hypotension systemically the patient Transport treat Ventilation with COVID-19 Work of breathing worsening [DOI] 10.1016/j.compbiomed.2021.105172 PMC 바로가기 [Article Type] Article
Myocardial perfusion SPECT findings in postCOVID periodArticle Published on 2022-02-012023-06-19 Journal: European Journal of Nuclear Medicine and Molecular [Category] COVID19(2023년), MERS, SARS, [키워드] COVID-19 Ischemia Perfusion Radionuclide imaging. [DOI] 10.1007/s00259-021-05552-4 PMC 바로가기
AI Lung Segmentation and Perfusion Analysis of Dual-Energy CT Can Help to Distinguish COVID-19 Infiltrates from Visually Similar Immunotherapy-Related Pneumonitis Findings and Can Optimize Radiological WorkflowsArticle Published on 2021-12-232022-10-29 Journal: Tomography [Category] COVID-19, SARS, [키워드] 105 patient artificial intelligence blinded BMI Can Concentration COVID-19 Diagnosis dual energy faster finding greater ICC Impact Infiltrate Intraclass correlation coefficient investigated linear mixed model Metrics no significant difference patients with COVID-19 Perfusion Pneumonitis pulmonary lobe radiologist Radiologists Ratio scored Segmentation selected significantly significantly higher tomography Validity vessel Volume was determined was measured was used X-ray computed [DOI] 10.3390/tomography8010003 PMC 바로가기 [Article Type] Article
Functional Trimeric SARS-CoV-2 Envelope Protein Expressed in Stable CHO CellsBioengineering and Biotechnology Published on 2021-12-172022-10-31 Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome Cell cellular CHO cell coronavirus COVID-19 pandemic COVID–19 CR3022 described docking domain envelope envelope protein expressing expression Extracellular infection mechanism infection with SARS-CoV-2 integrated bioprocessing Interaction mandatory membrane-bound mutant pandemic parameter Perfusion Protein protocol purification Recombinant spike protein responsible robust S-protein SARS CoV-2 SARS-CoV-2 similarity spike (S) glycoprotein Spike protein STABLE surface protein surface proteins the receptor-binding domain the spike protein therapeutic drug trimeric variant viral envelope proteins virus β-coronavirus [DOI] 10.3389/fbioe.2021.779359 PMC 바로가기 [Article Type] Bioengineering and Biotechnology
Myocardial Perfusion Imaging After Severe COVID-19 Infection Demonstrates Regional Ischemia Rather Than Global Blood Flow ReductionCardiovascular Medicine Published on 2021-12-072022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] age Analysis anatomical arteries association blood flow Cardiac MRI case-control study characterized chest pain co-morbidity Cohort Control coronary disease COVID-19 COVID-19 patient determine disease Ejection fraction Evidence Flow healthy volunteer Hospitalized hospitalized COVID-19 identify imaging implicated Infarction Infection intensive care IQR Ischemia LVEF male mechanism median Microvascular dysfunction Microvascular thrombosis Myocardial myocardial blood flow myocardial damage Myocardial infarction myocarditis Patient Perfusion Prevalence recovered patients Regional scar severe COVID-19 Sex Stress ventricular [DOI] 10.3389/fcvm.2021.764599 PMC 바로가기 [Article Type] Cardiovascular Medicine
Abnormalities in Cutaneous Microcirculation in Patients with Alzheimer’s Disease, Mild Cognitive Impairment, and Chronic Insomnia DisorderArticle Published on 2021-12-072024-09-02 Journal: Journal of Clinical Medicine [Category] 대상포진, [키워드] autonomic laser Doppler flowmetry microangiopathy parasympathetic Perfusion sympathetic [DOI] 10.3390/jcm10245718 PMC 바로가기 [Article Type] Article
Retinal microvascular and perfusional disruption in paediatric COVID-19: A case-control optical coherence tomography angiography study소아 COVID-19의 망막 미세혈관 및 관류 장애: 증례 대조군 광간섭 단층촬영 혈관조영술 연구Article Published on 2021-12-012022-09-11 Journal: Photodiagnosis and photodynamic therapy [Category] SARS, 치료기술, [키워드] acute phase age Analysis Asymptomatic capillary network Case-control case-control study changes children choroid Choroidal thickness Coherence Control Coronavirus 2019 COVID-19 COVID-19 patient cross-sectional detect disease follow-up study Foveal avascular zone group groups healthy children impairment Inflammation inflammatory site inflammatory sites location Macular material no significant differences Optical coherence tomography Patient pediatric Pediatric age Pediatric patient Perfusion Perfusion density recovered COVID-19 patient Recovered COVID-19 patients Retinal Significant significant difference significant differences significantly subgroup two group two groups undergo vessel Vessel density was impaired were measured [DOI] 10.1016/j.pdpdt.2021.102577 PMC 바로가기 [Article Type] Article
Lung Perfusion Scintigraphy Early After COVID-19: A Single-Center Retrospective StudyImaging Published on 2021-12-012022-10-30 Journal: Journal of Nuclear Medicine Technology [Category] COVID-19, SARS, [키워드] 14 subject 95% CI age analyzed Anticoagulant anticoagulation Confirmed coronavirus disease COVID-19 D-dimer D-dimer level early–post-COVID-19 patients evaluated Evidence higher risk Hospitalization hypoxia identify incidence Infection lung lung perfusion scan median interval men Novel coronavirus disease 2019 Odds ratio Patient Perfusion Post-COVID-19 patients Prevalence Prophylactic Prophylaxis regression analysis risk risk factor Scintigraphy serum study population subject subsegmental Support thromboembolic complication Thromboembolism Visual was used women [DOI] 10.2967/jnmt.121.262440 PMC 바로가기 [Article Type] Imaging
[COVID-19-induced coagulopathy and thrombosis manifestations][COVID-19로 인한 응고장애 및 혈전증 증상]Review Published on 2021-10-012022-09-11 Journal: Radiologe [Category] MERS, SARS, 진단, 치료기술, [키워드] (coronavirus disease 2019 Acetylsalicylic acid antiplatelet Antiplatelet drugs appear Basis changes clinical Coagulopathy Computedtomography coronavirus disease Coronavirus disease 2019 COVID-19 diagnostics disease dosage drug English Evidence heparin heparins hospitalized patient hospitalized patients hypoperfusion increasingly indicated low molecular weight Low molecular weight heparins lung Lungs Multiorgan organ systems Pathologies Perfusion perfusion disorders proportion radiological Radiological Diagnosis Regional SARS-CoV‑2 secondary prevention sense Standard standard treatment systemic disease therapeutic intervention therapy thrombosis Treatment Vascular vascular changes Vasculopathy virus Virus Disease [DOI] 10.1007/s00117-021-00901-8 PMC 바로가기 [Article Type] Review
Pharmacokinetics and Safety of XAV-19, a Swine Glyco-humanized Polyclonal Anti-SARS-CoV-2 Antibody, for COVID-19-Related Moderate Pneumonia: a Randomized, Double-Blind, Placebo-Controlled, Phase IIa StudyCOVID-19 관련 중등도 폐렴에 대한 돼지 당-인간화 다클론성 항-SARS-CoV-2 항체인 XAV-19의 약동학 및 안전성: 무작위 배정, 이중 맹검, 위약 대조, IIa상 연구Clinical Trial Published on 2021-08-172022-09-11 Journal: Antimicrobial Agents and Chemotherapy [Category] SARS, 비임상, 임상, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration adverse event adverse events anti-SARS-CoV-2 antibody antibody baseline characteristics body weight breath C max Characteristics Concentration concentrations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated drug during treatment enrolled evaluate group hypersensitivity IIa in vitro infusion inhibitory concentration intravenous dose maximum serum concentration median moderate Neutralizing activity optimal dose Patient Perfusion pharmacokinetics phase phase IIa Placebo Pneumonia polyclonal polyclonal antibody polyclonal glyco-humanized anti-SARS-CoV-2 antibody. Predictive Randomized reaction receive Registered reported Safety SARS-CoV-2 Serious Adverse Event Serious Adverse Events serum serum concentrations severe acute respiratory syndrome Coronavirus study drug Tolerability Treatment Trial XAV-19 [DOI] 10.1128/AAC.01237-21 PMC 바로가기 [Article Type] Clinical Trial