Perturbation – Page 2 – Communicable Diseases Research

A cautionary note on altered pace of aging in the COVID-19 era

코로나19 시대 고령화 속도 변화에 대한 주의사항

Article

Published on 2022-07-012022-09-11
Journal: Forensic science international. Genetics [Category] COVID19(2023년), MERS, SARS, 바이오마커, 유전자 메커니즘,

Psychoneuroimmunology in the time of COVID-19: Why neuro-immune interactions matter for mental and physical health

Research article

Published on 2022-07-012022-10-05
Journal: Behaviour research and therapy [Category] COVID19(2023년), SARS, 비임상, 치료제,

Singular Interface Dynamics of the SARS-CoV-2 Delta Variant Explained with Contact Perturbation Analysis

접촉 섭동 분석으로 설명되는 SARS-CoV-2 Delta 변이체의 단일 인터페이스 역학

Article

Published on 2022-06-272022-09-11
Journal: Journal of Chemical Information and Modeling [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

[키워드] ACE2 Alpha Analysis angiotensin Beta can not changes in Contact contact with COVID-19 pandemic crystallographic structure Delta delta variant Delta variants Dihedral angle direct contact drastic Dynamics Epsilon explain FIVE Gamma human ACE2 receptor human Angiotensin-converting enzyme interface L452R mechanism of action molecular molecular dynamics Mutation outcome pandemic PCA Perturbation Principal component principal component analysis provoke raise RBD receptor Receptor binding domain residue SARS-CoV-2 variant similarity singular Spike protein Spike receptor binding domain T478K the SARS-CoV-2 the spike protein variant variants wild type
[DOI] 10.1021/acs.jcim.2c00350 PMC 바로가기 [Article Type] Article

Neuroimmune contributions to Alzheimer’s disease: a focus on human data

Reviews

Published on 2022-06-062022-10-05
Journal: Molecular Psychiatry [Category] 바이오마커, 신약개발,

Tracing the SARS-CoV-2 infection on the ocular surface: Overview and preliminary corneoscleral transcriptome sequencing

안구 표면의 SARS-CoV-2 감염 추적: 개요 및 예비 각막 공막 전사체 시퀀싱

Article

Published on 2022-04-012022-09-11
Journal: Experimental eye research [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술,

[키워드] absence ADAMTS4 Analysis AQP5 associable caused Cluster Clusters component Cornea Corneal Corneoscleral ring COVID-19 CTRL Cytokines DEGs differentially expressed gene Differentially expressed genes Donor down-regulated gene down-regulated genes enrichment analysis Eye bank gene expression profile Gene ontology Genes genomic genomic RNA GO analysis GO term IL6 Illumina inactive indicated infected individual infected individuals Infection interferon interferon pathway ISG ISG15 ISGs Local Manifestations MMP1 modulation molecular mechanism molecular mechanisms ocular Ocular surface pathway PCA PCA analysis performed Perturbation positive Post-mortem principal Principal component principal component analysis proinflammatory cytokines Protective qRT-PCR RNA RNA-sequencing RSAD2 SARS-CoV-2 SARS-CoV-2 RNA several gene several genes Support tears the interferon the SARS-CoV-2 tissue tracing transcriptional Transcriptome transcriptome analysis transcriptome sequencing virus was performed
[DOI] 10.1016/j.exer.2022.108975 PMC 바로가기 [Article Type] Article

Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells

Research

Published on 2022-03-172022-10-05
Journal: Nature Immunology [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘,

Landscape of Molecular Crosstalk Perturbation between Lung Cancer and COVID-19

폐암과 COVID-19 사이의 분자 누화 섭동의 풍경

Article

Published on 2022-03-152022-09-11
Journal: International Journal of Environmental Research an [Category] 유전자 메커니즘,

Longitudinal Tracking of Immune Responses in COVID-19 Convalescents Reveals Absence of Neutralization Activity Against Omicron and Staggered Impairment to Other SARS-CoV-2 Variants of Concern

COVID-19 회복기의 면역 반응에 대한 종단적 추적은 우려의 다른 SARS-CoV-2 변종에 대한 오미크론 및 시차 손상에 대한 중화 활성의 부재를 나타냅니다

Article

Published on 2022-03-142022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 진단, 치료기술,

[키워드] activity Against Alpha alpha and delta variants analyzed antibodies association B cell B cells Beta cellular immunity cellular response Cellular responses changes in clearance Cohort concern Correlation analysis COVID-19 decrease Delta Delta variants Evaluating flow cytometry Gamma humoral humoral and cellular immunity humoral immune response IgG antibody IgG titer immune Immunity indicate indicated individual investigated lack long-lasting longitudinal memory memory B cell memory B cells neutralization capacity neutralization test Neutralizing antibodies neutralizing antibody omicron Omicron variants Other Patient patients persistence Perturbation phenotype Prospective Study protection Protective response SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 variant SARS-CoV-2 variants sera spike Spike-specific memory B cells surrogate virus neutralization test the disease variant variants variants of concern Viral virus neutralization test was measured Wuhan strain
[DOI] 10.3389/fimmu.2022.863039 PMC 바로가기 [Article Type] Article

Cardiovascular disturbances in COVID-19: an updated review of the pathophysiology and clinical evidence of cardiovascular damage induced by SARS-CoV-2

Review

Published on 2022-03-092022-10-27
Journal: BMC Public Health [Category] COVID-19,

[키워드] angiotensin-converting enzyme-2 Asymptomatic binding cardiovascular cardiovascular damage cardiovascular disorder Cardiovascular disorders cardiovascular morbidity cardiovascular system cause clinical evidence coronavirus Coronavirus-2 COVID-19 Critical Cytokine storm disease disease manifestation Evolution expresse Follow-up imaging Infection intensive care Mild morbidity and mortality myocarditis outcome pathophysiology patients Perturbation phenotype Phenotypes Positron emission tomography receptor respiratory virus SARS-CoV-2 SARS-COV-2 infection severe disease significantly Symptomatic patients systemic Takotsubo cardiomyopathy the disease Thromboembolism Treatment virus
[DOI] 10.1186/s12872-022-02534-8 PMC 바로가기 [Article Type] Review

Cardiovascular disturbances in COVID-19: an updated review of the pathophysiology and clinical evidence of cardiovascular damage induced by SARS-CoV-2

COVID-19의 심혈관 장애 : SARS-COV-2에 의해 유도 된 심혈관 손상의 병리 생리학 및 임상 증거에 대한 업데이트 된 검토.

Review

Published on 2022-03-092022-09-10
Journal: BMC Public Health [Category] 치료기술,

[키워드] angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 Asymptomatic binding cardiovascular cardiovascular damage cardiovascular disorder Cardiovascular disorders cardiovascular morbidities cardiovascular morbidity cardiovascular system causative agent cause clinical evidence coronavirus coronavirus disease coronavirus disease-2019 Coronavirus-2 COVID-19 Critical cytokine Cytokine storm disease disease manifestation Evolution expresse Follow-up imaging Infection intensive care intensive care unit Mild Mild disease morbidity morbidity and mortality Most patients myocarditis outcome pathophysiology patients Perturbation phenotype Phenotypes Positron emission tomography receptor respiratory respiratory virus SARS-Co SARS-CoV-2 SARS-COV-2 infection severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 severe disease significantly Symptomatic patients systemic Takotsubo cardiomyopathy the disease Thromboembolism Treatment virus
[DOI] 10.1186/s12872-022-02534-8 PMC 바로가기 [Article Type] Review