Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and BenefitsReview Published on 2021-01-302022-10-31 Journal: Nutrients [Category] COVID-19, MERS, [키워드] Action candidate complementary COVID-19 current demonstrated Effect Efficacy Evidence flavonoids immune health immune system immunomodulating in silico in vitro in vivo nutraceutical other respiratory infections pharmacological treatments phytonutrients review SARS-CoV-2 therapeutic agent therapeutic intervention Treatment Validity Viral diseases viral infections viruses [DOI] 10.3390/nu13020464 PMC 바로가기 [Article Type] Review
Neprilysin expression and functions in development, ageing and disease발달, 노화 및 질병에서의 네프릴리신 발현 및 기능Review Published on 2020-12-012022-08-31 Journal: Mechanisms of ageing and development [Category] MERS, SARS, 바이오마커, [키워드] Ageing AICD Alzheimer's disease Alzheimer’s disease amyloid-degrading enzyme angiotensin angiotensin receptor blocker approved Aβ peptide brain development CALLA Cancer CD10 cell proliferation changes in cognitive cognitive behaviour Compound cortex COVID-19 pathogenesis diabetes disease EGCG embryogenesis endopeptidase endopeptidase 24.11 enkephalinase enzyme Epigenetic epigenetic regulation expression foetal development function functions green tea HDACs heart failure hippocampus hypertension hypoxia immune response implicated inhibitor Intensive kidney membrane-bound memory NEP inhibitors olfactory bulbs neprilysin obesity olfactory Organisms Pathogenesis pathological conditions Pathologies peptide pharmacological treatment pharmacological treatments physiological functions prenatal prenatal hypoxia Prevent Preventive medicine Prostate cancer proteolytic receptor blocker Regulation Research Sacubitril striatum striatum. substrate substrates suggested therapeutic target Treatment type-2 diabetes upregulating valsartan [DOI] 10.1016/j.mad.2020.111363 PMC 바로가기 [Article Type] Review
Impact of COVID‐19 pandemic lockdown on narcolepsy type 1 managementOriginal Research Published on 2020-11-282022-10-28 Journal: Brain and Behavior [Category] Coronavirus, SARS, [키워드] Abstract ameliorated behavioral therapy BMI body mass index Combination coronavirus disease COVID‐19 COVID‐19 current eight extension groups Impact Intervention Italy lockdown males management Narcolepsy narcolepsy type 1 no significant difference nocturnal not differ objective pandemic Patient patient groups performed pharmacological treatments presenting reported Result significant increase significantly increased smart working Symptom management symptom severity the patient Treatment while [DOI] 10.1002/brb3.1955 PMC 바로가기 [Article Type] Original Research
Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly populationReview Published on 2020-11-062022-10-29 Journal: Seminars in immunopathology [Category] COVID-19, MERS, SARS, [키워드] age boost candidate clinical study clinical testing Comorbidities complex COVID-19 cytokine effective Effectiveness effort exacerbate Factor fraction help identify immune responses immune responsiveness immunopathological immunosenescence inflammaging lack marker mechanism Older older population overlap pharmacological treatments phenotype Prognosis recent response risk robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 vaccine Systems biology tested vaccination vaccination efficacy Vaccination strategy Vaccine Vaccine development vaccine response virulence [DOI] 10.1007/s00281-020-00821-0 PMC 바로가기 [Article Type] Review
A role of glycation and methylation for SARS-CoV-2 infection in diabetes?당뇨병에서 SARS-CoV-2 감염에 대한 당화 및 메틸화의 역할?Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 바이오마커, 진단, [키워드] ACE2 ACE2 expression adipose Adipose tissue affected Amino acid angiotensin Angiotensin II Angiotensin-converting enzyme angiotensin-converting enzyme 2 Biomarker blockers Cancer Comorbidity conditions COVID-19 demonstrated diabete diabetes DNA methylation enzyme Extracellular Glycation glycemic control high mortality rate human cells hydrogen hypertension IMPROVE insulin insulin resistance Interaction Intervention involved islet liver lysine Methylation muscle obesity observation outcome patients with diabete peripheral tissue peripheral tissues pharmacological treatments predict Protein RBD receptor Receptor binding domain Receptor Blockers residue responsible risk SARS-CoV-2 SARS-COV-2 infection suggested T2D target tertiary structure the SARS-CoV-2 tissue treated Trigger triggers type-2 diabetes upregulation [DOI] 10.1016/j.mehy.2020.110247 PMC 바로가기 [Article Type] Article
Current pharmacological treatments for SARS-COV-2: A narrative reviewArticle Published on 2020-06-272023-07-01 Journal: European journal of pharmacology [Category] SARS, [키워드] clinical trials coronavirus COVID-19 pharmacological treatments SARS-CoV-2 Therapies [DOI] 10.1016/j.ejphar.2020.173328 PMC 바로가기 [Article Type] Article
Vaccines against Coronaviruses: The State of the ArtReview Published on 2020-06-172022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] absence accelerate acute respiratory syndrome Affect animal model approved candidate carried caused concerning contagious contagiousness coronavirus Coronavirus vaccines country COVID-19 Efficacy Epidemic Epidemics First wave health system IMPROVE less MERS MERS-CoV Middle East new coronavirus SARS-CoV-2 occur pandemic Perspective pharmacological treatments Prognosis responsible SARS SARS-CoV SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 vaccine shown state subsequent syndrome the disease the vaccine Treatment Trial Vaccine vaccine candidate virus [DOI] 10.3390/vaccines8020309 PMC 바로가기 [Article Type] Review
Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 InfectionsBioengineering and Biotechnology Published on 2020-05-262022-10-31 Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19, [키워드] Administered Advancing anti-inflammatory agents Anti-viral attenuate Beat Can caused clinical trial clinical utility Combination coronavirus (2019-nCoV) COVID-19 COVID-19 disease curative Cytokine storm disease EVs Exosome extracellular vesicle Extracellular vesicles immunomodulatory IMPROVE Inflammation intravenously investigated lung damage lung injuries mainstream majority mechanism Medicine MSC MSCs outcome Patient people with COVID-19 pharmacological treatments regenerative properties reported risk SARS-CoV-2 SARS-CoV-2 virus secreted STEM stem cell Stem cell therapy survival therapeutic agents therapeutic effect therapeutic potential therapeutic strategy Therapies therapy Treatment treatment for COVID-19 Trial while [DOI] 10.3389/fbioe.2020.00554 PMC 바로가기 [Article Type] Bioengineering and Biotechnology
Current pharmacological treatments for COVID‐19: What’s next?Article Published on 2020-05-152023-06-15 Journal: British Journal of Pharmacology [Category] MERS, SARS, [키워드] antiinflammatory agents antivirals Clinical practice Clinical research COVID‐19 immuno‐modulatory agents pharmacological treatments [DOI] 10.1111/bph.15072 PMC 바로가기
COVID-19: a basic approach to understanding potential treatmentsReview Published on 2020-01-012023-07-05 Journal: Gaceta médica de México [Category] SARS, [키워드] COVID-19 pharmacological treatments renin-angiotensin system Sistema renina-angiotensina Tratamientos farmacológicos. [DOI] 10.24875/GMM.M21000459 [Article Type] Review