Prevalence and Risk Factors of SARS-CoV-2 Infection among Parturients and Newborns from Luanda, AngolaArticle Published on 2021-11-162022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] age Angola Antenatal carried China consequence COVID-19 COVID-19 case creating cross-sectional disease Factor Follow-up Infection intensive management investigated Luanda maternal breastfeeding mother Neonate Newborn newborn screening parturient Pharyngeal swab positive Pregnancy pregnant women previous study public health Rapid remains uncertain risk factor RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission Seven severity tested Testing Transmission [DOI] 10.3390/pathogens10111494 PMC 바로가기 [Article Type] Article
Prolonged rectal shedding of SARS-CoV-2 in a 22-day-old-neonate: a case reportCase Report Published on 2021-11-122022-10-28 Journal: BMC Pediatrics [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Admission Adults Asymptomatic Case report cause characterized children clinical picture clinical study coronavirus COVID-19 determine Diagnosis discharged disease course enrolled heart failure hospital initial Intervention intestine investigated Mild Mild symptom Neonate Neonates normalized novel coronavirus disease occurred Pharyngeal swab positive potential risk Prolonged rectal Rectal shedding rectal swab remained Research SARS-CoV-2 Tachycardia tested transfer Transmission [DOI] 10.1186/s12887-021-02976-7 PMC 바로가기 [Article Type] Case Report
Beware of pharyngeal Fusobacterium nucleatum in COVID-19Covid-19에서 인두 푸소 박테리아 핵 신경을 조심하십시오Research Published on 2021-10-112022-09-10 Journal: BMC Microbiology [Category] MERS, 바이오마커, 유전자 메커니즘, [키워드] adjusted alteration an area AUC Bacterial Biomarker Classifier clinician Coinfection Control COVID-19 COVID-19 patient COVID-19 patients Dysbiosis Faecalibacterium Faecalibacterium prausnitzii fecal Female patients Fusobacterium Fusobacterium nucleatum gastrointestinal disease groups Gut healthy controls higher risk Increased male metagenomic Metagenomic next-generation sequencing Microbiome Next-generation sequencing opportunistic pathogen Opportunistic Pathogens pathogen Pathogens pharyngeal Pharyngeal swab positive qPCR remained respiratory respiratory infection Result SARS-CoV-2 SARS-CoV-2 test significantly increased supplementary material the healthy Viral viral respiratory infection [DOI] 10.1186/s12866-021-02336-6 PMC 바로가기 [Article Type] Research
Bowel ischemia as onset of COVID‐19 in otherwise asymptomatic patients with persistently negative swabBrief Report Published on 2021-10-082022-10-30 Journal: Journal of internal medicine [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Asymptomatic asymptomatic patient blood vessels bowel bowel ischemia Case report clinical manifestation condition consecutive patient coronavirus 2 COVID‐19 COVID‐19 determine develop distress events hypercoagulable intestinal intestinal resection Ischemia manifestation Necrosis Patient Pharyngeal swab polymerase chain positive presenting repeated respiratory Result SARS‐CoV‐2 SARS‐CoV‐2 specimen Swab Symptom Symptoms tested the patient thrombosis tissue tissues Vascular vascular event was performed [DOI] 10.1111/joim.13385 PMC 바로가기 [Article Type] Brief Report
Enriched Opportunistic Pathogens Revealed by Metagenomic Sequencing Hint Potential Linkages between Pharyngeal Microbiota and COVID-19인두 미생물총과 COVID-19 사이의 잠재적 연관성을 암시하는 Metagenomic 시퀀싱으로 밝혀진 풍부한 기회 병원체Article Published on 2021-10-012022-09-11 Journal: Virologica Sinica [Category] SARS, 유전자 메커니즘, [키워드] ACE2 Affect Analysis Bacterial infections bacterial specy Campylobacter Combined cough COVID-19 COVID-19 group COVID-19 patient discriminant analysis experiments expression Fever Generalized linear model healthy Host immune response immune system in vitro indicated Infection Linear Discriminant Analysis linkage Metagenome sequencing metagenomic metagenomic sequencing microbiota modulate non-COVID-19 group pathogen Pathogens Patient patients with COVID-19 performed Pharyngeal swab Potential Previous studies previous study Prevotella promote receptor ACE2 respiratory tract Revealed SARS-CoV-2 SARS-COV-2 infection secondary bacterial infection Secondary bacterial infections stimulate Strains Streptococcus Symptom two group upper respiratory tract Vero Cell Vero cells virus Virus-host interaction Virus-host interactions [DOI] 10.1007/s12250-021-00391-x PMC 바로가기 [Article Type] Article
Can a modified-simplified pulmonary embolism severity index (m-sPESI) be used to predict the need for intensive care in hospitalized COVID-19 patients?수정-단순 폐색전증 중증도 지수(m-sPESI)를 사용하여 입원한 COVID-19 환자의 집중 치료 필요성을 예측할 수 있습니까?Article Published on 2021-10-012022-09-11 Journal: Journal of Thrombosis and Thrombolysis [Category] MERS, 바이오마커, [키워드] acute respiratory syndrome advanced age age Analysis approach AUC C-reactive protein C-reactive protein (CRP CAD Can Care cause Chain Reaction clinical manifestation clinical manifestations clinician coronavirus disease Coronavirus disease 2019 Coronavirus-2 Course COVID-19 COVID-19 disease COVID-19 infection COVID-19 patient COVID-19 patients detect develop diagnosis of COVID-19 disease examined female fibrinogen Health Organization Healthcare provider healthcare providers hemoglobin Hospitalized hospitalized COVID-19 hospitalized patients ICU admission identify imperative intensive care intensive care unit lab male malignancy mechanical ventilatory support Mild moderate moderate to severe morbidity Mortality multivariable logistic regression Multivariable logistic regression analysis nasal pandemic Patient patients PCR PESI Pharyngeal swab polymerase chain polymerase chain reaction positive predict pulmonary Pulmonary thromboembolism respiratory respiratory symptoms risk risk factor Risk factors SARS-CoV-2 scoring system sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome-associated coronavirus-2 Severe case severe respiratory symptoms severity significantly higher single center specificity SPESI the disease the patient thrombosis Treatment troponin Troponin-I Univariate analysis Validity ventilatory support WHO with COVID-19 World Health Organization [DOI] 10.1007/s11239-021-02405-7 PMC 바로가기 [Article Type] Article
SARS-CoV-2: Viral Loads of Exhaled Breath and Oronasopharyngeal Specimens in Hospitalized Patients with COVID-19SARS-CoV-2: COVID-19로 입원한 환자의 호기 및 구강 비인두 표본의 바이러스 부하Article Published on 2021-09-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 변종, 치료기술, [키워드] Airborne transmission Assessing breath Chain Reaction COVID-19 COVID-19 patient Delta examined Exhaled Breath Hospitalization hospitalized COVID-19 patients hospitalized patient hospitalized patients individual infectiousness load no correlation noninvasive Pharyngeal swab polymerase chain polymerase chain reaction positive proof of concept Quantitative Respiratory droplets reverse transcription SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection SARS-CoV-2 viral load significantly higher specimen Swab tested variant Viral load viral loads was determined was performed widespread with COVID-19 [DOI] 10.1016/j.ijid.2021.07.012 PMC 바로가기 [Article Type] Article
Laryngotracheal aspiration test reduce the false negative rate in patients with suspected SARS-COV-2 pneumonia despite a negative nasopharyngeal swabObservational Study Published on 2021-09-012022-10-05 Journal: European journal of internal medicine [Category] SARS, 임상, [키워드] Accuracy adverse events BAL Bronchoalveolar lavage consecutive patient COVID-19 cross-sectional definitive diagnosis diagnose diagnosed Diagnosis Emergency emergency department enrolled evaluate False negative rate false negative results feasible final diagnosis hospital hospitals Laryngotracheal aspiration limitations LTA majority Nasopharyngeal swab Negative predictive value not be collected NPs Patient patients performed Pharyngeal swab Pneumonia positive pulmonary diseases reduce reduced Safe SARS-CoV-2 specimen sputum Strategy time-consuming was performed [DOI] 10.1016/j.ejim.2021.06.019 PMC 바로가기 [Article Type] Observational Study
Diagnostic performance of a colorimetric RT -LAMP for the identification of SARS-CoV-2: A multicenter prospective clinical evaluation in sub-Saharan AfricaResearch Paper Published on 2021-08-282022-10-31 Journal: EClinicalMedicine [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome African appear Asymptomatic Cameroon caused clinical evaluation comparable conducted coronavirus coronavirus SARS-CoV-2 COVID-19 COVID-19 pandemic cycle threshold dependent on detection diagnostic Diagnostic accuracy Ethiopia evaluate extrinsic finding foundation funding individual infected individual intrinsic isothermal amplification Italy Kenya management Melinda Gate multicenter multicentre Negative predictive value Nigeria observational study Pharyngeal swab polymerase chain Positive predictive value prevention of COVID-19 Prospective prospective observational study real time reverse transcription Reverse transcription loop-mediated isothermal amplification RLS RNA RT LAMP RT-LAMP RT-PCR SARS-CoV-2 sensitivity Sensitivity and specificity specificity specimen specimens sub-Saharan Africa subset Trial Viral load Viral RNA virus was determined was tested [DOI] 10.1016/j.eclinm.2021.101101 PMC 바로가기 [Article Type] Research Paper
Subacute SARS-CoV-2 replication can be controlled in the absence of CD8+ T cells in cynomolgus macaques아급성 SARS-CoV-2 복제는 시노몰구스 원숭이에 CD8+ T 세포가 없을 때 제어할 수 있습니다.Research Article Published on 2021-07-192022-09-10 Journal: PLoS Pathogens [Category] SARS, 진단, 치료기술, [키워드] absence administration Analysis anti-CD8 antibody Antibody titers Arm Asymptomatic CD8 Cell clinical manifestation clinical manifestations comparable contribute convalescent individuals cynomolgus macaques days post-infection deficiency determinant determinants effectors eight examined failure fatal disease FIVE functional immune in viral Infection inoculated intranasally Kinetics lead Lymph node macaque macaques monoclonal Nasopharyngeal swab nasopharyngeal swabs necropsy Neutralizing antibody titer pharyngeal mucosa Pharyngeal swab plasma Post-infection progression Respiratory failure retropharyngeal lymph node RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication SARS-CoV-2 RNA Subacute T cell T cells T-cell dysfunction T-cell Response T-cell responses TCID treated undetectable Viral viral control viral replication Viral RNA [DOI] 10.1371/journal.ppat.1009668 PMC 바로가기 [Article Type] Research Article