Efficient inactivation of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in human apheresis platelet concentrates with amotosalen and ultraviolet A lightamotosalen 및 자외선 A 광선으로 인간 성분채집 혈소판 농축액에서 중증 급성 호흡기 증후군 코로나바이러스-2(SARS-CoV-2)의 효율적인 비활성화Article Published on 2022-02-012022-09-11 Journal: Transfusion clinique et biologique : journal de la [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome Amotosalen Asymptomatic Blood Blood safety cell line collected conducted Coronavirus-2 donors Efficacy efficient English followed by French genomic human coronaviruses in vitro experiments inactivated inactivation inhibited limit of detection Log reduction material MERS MERS-CoV mitigate negative controls nucleic acid Nucleic acid detection Particle passage pathogen Pathogen reduction Plaque assay plasma Platelet platelet concentrate platelet concentrates Platelets positive potential risk Quantitative Quantitative RT-PCR raised reduction Réduction des agents pathogènes RT-PCR SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 RNA Sécurité transfusionnelle. System titre transfusion Transmission Treatment ultraviolet viral particle Viral particles viral replication viral titer [DOI] 10.1016/j.tracli.2021.08.005 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Remains Infectious on Refrigerated Deli Food, Meats, and Fresh Produce for up to 21 DaysArticle Published on 2022-01-212022-11-01 Journal: Foods [Category] COVID-19, [키워드] antiviral effects cause Cooking COVID-19 Day determine exhibited fat food food contamination food handling foodborne transmission Fresh highlighting inactivated infect Infection Infectious virus ingestion intestinal cells medium occur pathogen PCR-based assay Plaque assay processed Produce Protein qRT-PCR remained risk of infection SARS-CoV-2 source of infection Support survival thermal processing Viral RNA virus [DOI] 10.3390/foods11030286 PMC 바로가기 [Article Type] Article
Identification and characterisation of SARS-CoV-2 and Human alphaherpesvirus 1 from a productive coinfection in a fatal COVID-19 case치명적인 COVID-19 사례에서 생산적인 동시 감염에서 SARS-CoV-2 및 인간 알파헤르페스바이러스 1의 식별 및 특성화Research Article Published on 2022-01-102022-09-10 Journal: Memórias do Instituto Oswaldo Cruz [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplicon-based sequencing Analysis approach can not causal relationship Chain Reaction characterisation Coinfection collected Coronaviridae coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity determine Diagnosis etiological agent explain fatal COVID-19 Genetic variant herpes simplex virus Herpes Simplex Virus 1 Herpesviridae high viral load HSV-1 Human identification Infection metagenomic Nasopharyngeal swab nasopharyngeal swab sample Neurological symptom Neurological symptoms neutralisation test outcome Patient PCR performed plaque Plaque assay plaque phenotypes polymerase chain polymerase chain reaction predominant reduction respiratory responsible reverse transcription reverse transcription real-time polymerase chain reaction RT-qPCR SARS-CoV-2 SARS-CoV-2 strain Sequencing severe symptom severe symptoms severity strain Strains suggested Support the disease Viral Viral load Virological virus [DOI] 10.1590/0074-02760210176 PMC 바로가기 [Article Type] Research Article
Persimmon-derived tannin has antiviral effects and reduces the severity of infection and transmission of SARS-CoV-2 in a Syrian hamster model감에서 추출한 탄닌은 항바이러스 효과가 있으며 시리아 햄스터 모델에서 SARS-CoV-2의 감염 및 전염의 심각성을 감소시킵니다.Article Published on 2021-12-082022-09-10 Journal: Scientific Reports [Category] SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition administration antioxidant Antiviral effect antiviral effects approach carboxymethyl cellulose caused Cellulose control group coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Donor dose hamster help human-to-human transmission immunology in vitro in vivo models inoculated investigated Microbiology oral administration oral cavity Persimmon Plaque assay Pneumonia Prevent reduce reduced respiratory Saliva SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severity Severity of infection Spread suppressed tannin These data Transmission transmission of SARS-CoV-2 transmitted uninfected virus virus titer virus titers [DOI] 10.1038/s41598-021-03149-3 PMC 바로가기 [Article Type] Article
Porcine Deltacoronavirus Utilizes Sialic Acid as an Attachment Receptor and Trypsin Can Influence the Binding ActivityArticle Published on 2021-12-062022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] acid activity Adsorption alleviate aminopeptidase N atomic attachment binding Can carbohydrate carbohydrates cause Cell cell membrane cells Critical demonstrated dependent on diarrhea distribution ENhance entry receptor facilitate functional in vivo experiments Infection influence Interaction intestine Invasion involved mechanism Microscopy Novel coronavirus Plaque assay Porcine deltacoronavirus promoted provide receptor sialic acid significantly susceptibility trypsin virus western blotting [DOI] 10.3390/v13122442 PMC 바로가기 [Article Type] Article
Rapid determination of infectious SARS-CoV-2 in PCR-positive samples by SDS-PMA assisted RT-qPCRSDS-PMA 지원 RT-qPCR을 통한 PCR 양성 샘플의 감염성 SARS-CoV-2의 신속한 측정Article Published on 2021-11-252022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, [키워드] assistance circumvent comparable conditions conjugate COVID-19 COVID-19 pandemic Ct value Culture Cutoff dead detect experiment facilitate Formation gold gold standard groups Health Health crisis heat heat-inactivated inactivated inactivation infectious particles less Live virus management MONITOR nucleic acid Patient PCR amplification PCR-positive Plaque assay PMA Prevent Rapid reduce released RT-qPCR SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2 transmission SARS-CoV-2 virion SDS storage Viral particles Viral RNA virion virions [DOI] 10.1016/j.scitotenv.2021.149085 PMC 바로가기 [Article Type] Article
Antibody cocktail effective against variants of SARS-CoV-2SARS-CoV-2 변종에 효과적인 항체 칵테일Research Published on 2021-11-232022-09-10 Journal: Journal of Biomedical Science [Category] MERS, SARS, 변종, 진단, [키워드] (Alpha) (Beta) acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha analyzed antibody antibody cocktail B.1.1.7 B.1.351 B.1.429 B.1.526 B.1.617.1 B.1.617.2 Beta binding ability binding activity Brazil caused circulating SARS-CoV-2 variant cocktail Cocktail therapy Combination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Delta effective Efficacy Epsilon evaluate exhibited Gamma hamsters high mutation rate India Iota mutation rate neutralization Neutralizing neutralizing activities Neutralizing activity Neutralizing antibodies neutralizing antibody new SARS-CoV-2 New York Plaque assay plaque assays Post-infection PRNT Prophylactic pseudovirus pseudoviruses Receptor-binding domain (RBD) respiratory Result retained RNA virus SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) South Africa Spike protein Spike proteins tested the SARS-CoV-2 the spike protein therapeutic effect Treatment United Kingdom Vaccine variant variants variants of SARS-CoV-2 [DOI] 10.1186/s12929-021-00777-9 PMC 바로가기 [Article Type] Research
Clinical severe acute respiratory syndrome coronavirus 2 isolation and antiviral testingProtocol Published on 2021-11-202023-06-15 Journal: Antiviral chemistry & chemotherapy [Category] MERS, [키워드] antiviral assay Plaque assay severe acute respiratory syndrome coronavirus 2 variant virus isolation [DOI] 10.1177/20402066211061063 PMC 바로가기 [Article Type] Protocol
Curcumin Inhibits In Vitro SARS-CoV-2 Infection In Vero E6 Cells through Multiple Antiviral MechanismsCurcumin은 다중 항바이러스 메커니즘을 통해 Vero E6 세포의 시험관 내 SARS-CoV-2 감염을 억제합니다Article Published on 2021-11-162022-09-10 Journal: Molecules [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료제, [키워드] addition Affect anti-inflammatory effect anti-inflammatory property Antiviral antiviral activity Antiviral effect COVID-19 Curcumin Cytokines cytotoxicity D614G D614G strain delta variant ELISA evaluated exhibit exhibited IL-1β IL-6 IL-8 immune response in vitro independent Infection Inflammation inhibited investigated mononuclear cell mononuclear cells MTT Multiple PBMC PBMCs Peripheral blood Peripheral blood mononuclear cells Plaque assay Post-infection pro-inflammatory cytokine pro-inflammatory cytokines qPCR quantified released replicative required SARS-CoV-2 SARS-COV-2 infection scarcity the SARS-CoV-2 Therapeutic approach therapeutic approaches to define Treatment treatment strategy triggered Vero E6 VERO E6 cells Viral viral titer virucidal were used [DOI] 10.3390/molecules26226900 PMC 바로가기 [Article Type] Article
Detection of human coronavirus RNA in surgical smoke generated by surgical devices수술 장치에서 생성된 수술 연기에서 인간 코로나바이러스 RNA 검출Article Published on 2021-11-012022-09-11 Journal: The Journal of hospital infection [Category] SARS, 치료기술, 치료제, [키워드] addition Cell Chain Reaction clinical settings collected coronavirus coronavirus RNA cultured cells demonstrated detection Electric scalpel evaluate Evidence experiment facilitated filtration hazard human coronavirus hydrosol induce Infection infective Infectivity mitigate Patient plaque Plaque assay polymerase chain polymerase chain reaction quantitative polymerase chain reaction reduced referred to reverse transcription risk SARS-CoV-2 SARS-CoV-2 transmission smoke surgical Surgical smoke Transmission Ultrasonic Ultrasonic scalpel. viral infectivity Viral RNA virus was determined was used [DOI] 10.1016/j.jhin.2021.08.022 PMC 바로가기 [Article Type] Article