The Yin and Yang of Pneumolysin During Pneumococcal Infectionarticle Published on 2022-04-302024-09-01 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] cholesterol-dependent cytolysin plasma membrane Pneumolysin Pneumonia pore-forming toxin pro- and anti-inflammatory immune responses Streptococcus pneumoniae [Article Type] article
Inhibitory effect of hederagenin on Streptococcus pneumoniae pneumolysin in vitroarticle Published on 2022-03-312024-09-01 Journal: Microbes and Infection [Category] 폐렴구균 감염증, [키워드] Anti-virulence hederagenin Pneumolysin Streptococcus pneumoniae [Article Type] article
Platelets, Bacterial Adhesins and the Pneumococcus혈소판, 세균 부착 인자 및 폐렴구균Article Published on 2022-03-252024-08-24 Journal: Cells [Category] 폐렴구균 감염증, [키워드] MSCRAMMs platelet activation platelet killing Pneumolysin pore formation Staphylococcus aureus Streptococcus pneumoniae surface proteins toxin.
Pandemic Influenza Infection Promotes Streptococcus pneumoniae Infiltration, Necrotic Damage, and Proteomic Remodeling in the Heart전염병 인플루엔자 감염은 심장에서 폐렴구균 침투, 괴사성 손상 및 단백질체 재구성을 촉진한다.Article Published on 2022-01-042024-07-30 Journal: mBio [Category] 폐렴구균 감염증, [키워드] adhesion heart Influenza necroptosis Pneumolysin pore-forming toxins proteomics Secondary bacterial infections Streptococcus pneumoniae [DOI] 10.1128/mbio.03257-21 PMC 바로가기
Clarithromycin Inhibits Pneumolysin Production via Downregulation of ply Gene Transcription despite Autolysis Activation클라리트로마이신은 자가 용해 활성화에도 불구하고 ply 유전자 전사를 하향 조절하여 폐렴용혈소체 생산을 억제한다.Research Article Published on 2021-09-012024-07-30 Journal: Microbiology Spectrum [Category] 폐렴구균 감염증, [키워드] autolysis clarithromycin erythromycin Lung injury macrolides Neutrophil elastase Pneumolysin Pneumonia Streptococcus pneumoniae [DOI] 10.1128/Spectrum.00318-21 PMC 바로가기 [Article Type] Research Article
Reversion of Pneumolysin-Induced Executioner Caspase Activation Redirects Cells to Survival폐렴용혈소독소 유도 집행자 카스파제 활성화의 재전환은 세포를 생존으로 유도한다.Article Published on 2021-06-042024-08-24 Journal: Nanoscale [Category] 폐렴구균 감염증, [키워드] Apoptosis calcium cell survival Mitochondria Pneumolysin Streptococcus pneumonia
Pneumolysin Is Responsible for Differential Gene Expression and Modifications in the Epigenetic Landscape of Primary Monocyte Derived Macrophages폐렴용혈소는 1차 단핵구 유래 대식세포의 차별적인 유전자 발현 및 후생유전학적 환경의 변화를 담당한다.Original Research Published on 2021-05-112024-07-30 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] histone post translational modifications monocyte derived macrophages Pneumolysin Streptococcus pneumoniae tumour necrosis factor [DOI] 10.3389/fimmu.2021.573266 PMC 바로가기 [Article Type] Original Research
The Role of Neutrophils and Neutrophil Elastase in Pneumococcal Pneumonia폐렴구균 폐렴에서 호중구와 호중구 엘라스테이스의 역할Article Published on 2021-03-162024-07-30 Journal: Frontiers in Cellular and Infection Microbiology [Category] 폐렴구균 감염증, [키워드] Innate immunity neutrophil Neutrophil elastase Pneumolysin Pneumonia Streptococcus pneumoniae virulence factor [DOI] 10.3389/fcimb.2021.615959 PMC 바로가기
Preclinical in vitro and in vivo profile of a highly-attenuated, broadly efficacious pneumolysin genetic toxoid고도로 약화된, 광범위하게 효능이 있는 폐렴구균 독소의 전임상 인 비트로 및 인 비보 프로필Article Published on 2021-03-122024-08-24 Journal: Vaccine [Category] 폐렴구균 감염증, [키워드] mouse model Pneumolysin serotype replacement Serotype-independent pneumococcal vaccine Streptococcus pneumoniae Universal pneumococcal vaccine. [DOI] 10.1016/j.vaccine.2020.04.064
Streptococcus pneumoniae and Its Virulence Factors H 2 O 2 and Pneumolysin Are Potent Mediators of the Acute Chest Syndrome in Sickle Cell Disease폐렴구균과 그 독소 인자 H2O2 및 폐독소는 겸상적혈구병에서 급성 흉부 증후군의 강력한 매개체이다.Review Published on 2021-02-172024-07-30 Journal: Toxins [Category] 폐렴구균 감염증, [키워드] acute chest syndrome H2O2 Pneumolysin Sickle cell disease Streptococcus pneumoniae [DOI] 10.3390/toxins13020157 PMC 바로가기 [Article Type] Review