Targeting Myeloperoxidase Activity and Neutrophil ROS Production to Modulate Redox Process: Effect of Ellagic Acid and AnaloguesArticle Published on 2023-06-022024-08-29 Journal: Molecules [Category] 말라리아, [키워드] ellagic acid horseradish peroxidase malaria myeloperoxidase PMNs polyphenols reactive oxygen species
Supramolecular Polyphenol‐DNA Microparticles for In Vivo Adjuvant and Antigen Co‐Delivery and Immune StimulationDrug Delivery Published on 2023-02-102024-09-05 Journal: Angewandte Chemie (International ed. in English) [Category] update2024, [키워드] drug delivery Hybrid Materials polyphenols self-assembly Vaccines [DOI] 10.1002/anie.202214935 PMC 바로가기 [Article Type] Drug Delivery
Anti-hepatitis B virus activity of lithospermic acid, a polyphenol from Salvia miltiorrhiza, in vitro and in vivo by autophagy regulationArticle Published on 2023-02-102023-06-13 Journal: Journal of ethnopharmacology [Category] B형 간염, [키워드] Antiviral autophagy Hepatitis B virus Lithospermic acid polyphenols Traditional Chinese medicine [DOI] 10.1016/j.jep.2022.115896
Insights into Antiviral Properties and Molecular Mechanisms of Non-Flavonoid Polyphenols against Human HerpesvirusesReview Published on 2022-11-112023-06-02 Journal: International Journal of Molecular Sciences [Category] 두창, 홍역, [키워드] antiviral activity Epstein–Barr virus (EBV) herpes simplex virus HSV-1 HSV-2 human cytomegalovirus (HCMV) Kaposi sarcoma-associated herpesvirus (KSHV) natural products non-flavonoid polyphenols polyphenols Varicella-zoster virus (VZV) [DOI] 10.3390/ijms232213891 PMC 바로가기 [Article Type] Review
Hormonal regulation of health-promoting compounds in tea (Camellia sinensis L.)Review Published on 2022-08-152023-07-09 Journal: Plant physiology and biochemistry : PPB [Category] COVID19(2023년), [키워드] catechins health benefits Plant hormones polyphenols secondary metabolites Tea quality Theanine. [DOI] 10.1016/j.plaphy.2022.06.021 [Article Type] Review
In Silico and In Vitro Studies of Alchemilla viridiflora Rothm-Polyphenols’ Potential for Inhibition of SARS-CoV-2 InternalizationAlchemilla viridiflora Rothm-Polyphenols의 SARS-CoV-2 내재화 억제 가능성에 대한 실리코 및 체외 연구Article Published on 2022-08-142022-09-11 Journal: Molecules [Category] SARS, 변종, [키워드] ACE2 Alchemilla viridiflora Rothm. angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Antiviral agents binding binding energy binding interaction Compound computational studies Computational study Contact COVID-19 COVID-19 pandemic dose doses E484K effective Effectiveness exhibited flavonoid G476S glycoprotein Health higher affinity highest in silico in vitro inhibited inhibition internalization investigated K417N methanol molecular docking studies Molecular docking study Mutation N439K N501Y neuropilin Neuropilin-1 NRP1 outbreak plants polyphenols Potential Prevent quercetin receptor receptors resulting SARS-CoV-2 SARS-CoV-2 strain selected significantly spike glycoprotein tested V483A virus virus infection Virus spike wild strain [DOI] 10.3390/molecules27165174 PMC 바로가기 [Article Type] Article
In silico evaluation of Vitis amurensis Rupr. Polyphenol compounds for their inhibition potency against COVID-19 main enzymes Mpro and RdRpReview article Published on 2022-05-012022-10-05 Journal: Saudi Pharmaceutical Journal : SPJ [Category] 신약개발, 치료제, [키워드] anti-viral activity antiviral activities antiviral activity approach approved binding caffeic acid caused Characteristics Chinese Compound compounds COVID-19 COVID-19 disease docking study drug drug candidate drug-likeness drugs enzyme explained ferulic acid FIVE Health Infection Inhibitory effects molecular docking Molecular docking study MPro naringenin novel SARS-CoV-2 virus offer pandemic pharmacokinetic analysis Pneumonia polyphenol polyphenols quercetin RdRP RdRp active site recent Replication reported SARS-CoV-2 the SARS-CoV-2 therapeutic effect Transcription Transmission Treatment Vitis amurensis WHO World Health Organization [DOI] 10.1016/j.jsps.2022.02.014 [Article Type] Review article
A Phase II Study on the Effect of Taurisolo ® Administered via AEROsol in Hospitalized Patients with Mild to Moderate COVID-19 Pneumonia: The TAEROVID-19 StudyClinical Trial Published on 2022-04-292022-10-04 Journal: Cells [Category] COVID19(2023년), SARS, 임상, [키워드] Anti-inflammatory antioxidant effects clinical trial Compound conducted Controlled trial Coronavirus infections COVID-19 COVID-19 pandemic COVID-19 patients COVID-19 pneumonia demonstrated Effect Efficacy evaluate faster feasibility First wave hospitalized patient ICU ICU access intensive care patients treated phase plants polyphenol polyphenols SARS-CoV-2 pneumonia secondary metabolites Symptom Symptoms therapy Treatment Trial [DOI] 10.3390/cells11091499 PMC 바로가기 [Article Type] Clinical Trial
Molecular Interactions of Tannic Acid with Proteins Associated with SARS-CoV-2 InfectivityArticle Published on 2022-02-272022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 3CLpro ACE2 acid acute respiratory syndrome angiotensin-converting enzyme 2 approach bind binding biochemical building cell membrane Combination Compound coronavirus coronavirus disease COVID-19 Effect Extracellular higher affinity Host Infectivity inhibit Inhibition assays inhibitors Interaction involved Ligand molecular molecular docking molecular dynamics organism pandemic physicochemical polyphenols Prevent protease RBD Receptor binding domain Replication SARS-CoV-2 SARS-CoV-2 cell serine 2 Spike protein Structural properties target target receptor targets the SARS-CoV-2 TMPRSS2 transmembrane [DOI] 10.3390/ijms23052643 PMC 바로가기 [Article Type] Article
New Insights into Potential Beneficial Effects of Bioactive Compounds of Bee Products in Boosting Immunity to Fight COVID-19 Pandemic: Focus on Zinc and PolyphenolsReview Published on 2022-02-232022-10-30 Journal: Nutrients [Category] COVID-19, [키워드] acute respiratory syndrome Antiviral effect approach bee bee products caused chronic disease Complication Compound contribute coronavirus coronavirus disease COVID-19 develop diabetes dysfunction Effect Epidemic evaluate focus hypertension immune immune system Immunity immunomodulatory information insight natural products New polyphenol polyphenols Population Potential Prevent product reduce Research risk SARS-CoV-2 SARS-COV-2 infection serious complication severity of COVID-19 Symptom Symptoms viral infections Zinc [DOI] 10.3390/nu14050942 PMC 바로가기 [Article Type] Review