pro-inflammatory mediators – Page 2 – Communicable Diseases Research

Potential Immunomodulatory Properties of Biologically Active Components of Spices Against SARS-CoV-2 and Pan β-Coronaviruses

SARS-CoV-2 및 Pan β-Coronavirus에 대한 향신료의 생물학적 활성 성분의 잠재적 면역 조절 특성

Cellular and Infection Microbiology

Published on 2021-08-272022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 치료제,

Possible therapeutic effects of Nigella sativa and its thymoquinone on COVID-19

Covid-19에 대한 Nigella sativa와 Thymoquinone의 가능한 치료 효과

Review

Published on 2021-06-102022-08-31
Journal: Pharmaceutical Biology [Category] SARS, 치료제,

[키워드] animal Anti-inflammatory Antiviral antiviral effects cause Clinical studies clinical study clinical trial clinical trials Context COVID-19 database Effect Effects Efficacy flowering plant Google Scholar IFN-γ IgG1 IgG2a IL-12 IL-2 IL-4 IL-6 immunomodulation immunomodulatory effect immunomodulatory effects immunomodulatory properties immunomodulatory property infected patient infected patients ISI literature review mediators medicinal plant molecular docking Nigella Sativa Novel coronavirus objective Preliminary data pro-inflammatory mediator pro-inflammatory mediators Pulmonary function test randomize reduced respiratory respiratory disorders Respiratory system Result searched Serum level serum levels Severe infection suggested therapeutic effect thymoquinone Treatment Web of Science with COVID-19
[DOI] 10.1080/13880209.2021.1931353 PMC 바로가기 [Article Type] Review

Cytokine storm modulation in COVID-19: a proposed role for vitamin D and DPP-4 inhibitor combination therapy (VIDPP-4i)

Perspective

Published on 2021-04-282022-10-04
Journal: Immunotherapy [Category] MERS, SARS, 신약개발,

[키워드] Abstract acute respiratory syndrome Anti-inflammatory cardiovascular disease characterized combination therapy coronavirus COVID-19 Cytokine storm diabete diabetes Dipeptidyl peptidase-4 DPP-4 inhibitors Drug repurposing dysregulated immune response Evidence homeostasis immunomodulation immunomodulator immunomodulators immunomodulatory properties immunomodulatory property increasingly inhibitor inhibitors modulate modulation pathophysiology patients with diabete Prevent prevent disease progression pro-inflammatory cytokine pro-inflammatory mediators progression Regulation reported SARS-CoV-2 severe coronavirus disease shown synergistic the cytokine storm Therapeutic approach Treatment Type type 2 diabetes VIDPP-4i virulence Vitamin D
[DOI] 10.2217/imt-2020-0349 PMC 바로가기 [Article Type] Perspective

Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study

Research

Published on 2021-02-042022-10-05
Journal: Molecular Psychiatry [Category] SARS, 임상, 진단, 치료제,

[키워드] 95% CI adjusted adults hospitalized Analysis Antiviral effect AP-HP association biological marker Characteristics conducted COVID-19 Cox model death depressive disease severity disorder Endpoint epithelial cell examined Hospital admission hospitalized patient hospitals In-vitro Infection inhibit intubation lower risk medication Meta-analysis multicenter multiple sensitivity analyses multivariable Paris Patient patients hospitalized plasma Prevent primary analysis primary endpoint pro-inflammatory mediators Probability psychotropic medications randomized clinical trial recent reduced reduced risk remained retrospective cohort study SARS-CoV-2 severe COVID-19 university Weighting
[DOI] 10.1038/s41380-021-01021-4 [Article Type] Research

Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets

패혈증 관련 사이토카인 폭풍의 유료 유사 수용체 및 미래 면역 조절 표적으로서의 내인성 음성 조절자

Review

Published on 2020-12-012022-09-11
Journal: International immunopharmacology [Category] SARS, 유전자 메커니즘,

[키워드] activate Activation acute infections Acute inflammation cells chemokines COVID-19 cytokine Cytokine storm Cytokines damage DAMPs death Diseases downstream signaling pathway downstream signaling pathways expressed generate Genetic Host host cells host cells) Immune cell immune cells Immune homeostasis immunomodulatory implicated include induction inflammatory conditions Inflammatory diseases Inflammatory response Innate Innate immunity interferons lead maintain MAMP MAMPs mechanism mechanisms mediators MODS molecular pattern multi-organ dysfunction multi-organ failure negative feedback negative feedback mechanisms neurons nitrogen non-immune organ dysfunction oxygen PAMPs pandemic pathogen Pathogens Pathways Pattern recognition pattern recognition receptor persistence pro-inflammatory mediator pro-inflammatory mediators PRRs reactive oxygen Recognition recognize released repair ROS Sepsis severe COVID-19 subject syndrome systemic inflammatory target the patient therapeutic drug TLR TLR signaling TLR signaling pathways TLRs Toll-like receptor Toll-like receptors
[DOI] 10.1016/j.intimp.2020.107087 PMC 바로가기 [Article Type] Review

Persistence of Anti-SARS-CoV-2 Antibodies in Non-Hospitalized COVID-19 Convalescent Health Care Workers

Article

Published on 2020-10-012022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

[키워드] addressed affected anti-SARS-CoV-2 antibodies Antibody Response Antibody titer Blood collected correlation COVID-19 COVID-19 infections ELISA assay expressing full length General population healthcare worker ICU IgA antibody IgG IgM immune response Infection intensive care unit magnitude Patient patients hospitalized persistence Prevalence pro-inflammatory cytokine pro-inflammatory mediator pro-inflammatory mediators profile Protein question RBD Re-infection SARS-CoV-2 SARS-COV-2 infection sera Serological testing short duration spike subject tested the antibody the N protein viral clearance Viral protein worker
[DOI] 10.3390/jcm9103188 PMC 바로가기 [Article Type] Article

Immunological Criteria for Predicting Severe and Complicated Forms of Chickenpox

수두의 중증 및 합병증 형태 예측을 위한 면역학적 기준

Article

Published on 2020-08-272023-05-23
Journal: Modern Technologies in Medicine [Category] Fulltext, 대상포진, 두창, 수두, 홍역,

[키워드] Varicella zoster cellular immunity. Cytokines interferons neutrophils chemiluminescence polymerase chain reaction pro-inflammatory mediators
[DOI] 10.17691/stm2020.12.4.06 PMC 바로가기

Central nervous system complications associated with SARS-CoV-2 infection: integrative concepts of pathophysiology and case reports

Review

Published on 2020-08-062022-10-30
Journal: Journal of Neuroinflammation [Category] COVID-19, MERS,

[키워드] ACE2 activate acute respiratory syndrome ARDS Autoimmunity beta-coronavirus blood-brain barrier Brain C-reactive protein Case report caused Central nervous system chemokines CNS Complication contributing to coronavirus Coronavirus disease 2019 CoV COVID-19 CoVs Critical CRP Cytokines Direct disorders disrupt dysregulation elevated Encephalitis Encephalopathy endothelial cells endothelial function Endotheliitis Fever highlight hyper-inflammation Hyperferritinemia hypoxemic illnesses impair include induce Inflammatory responses innate immune Innate immunity lymphocytopenia MERS-CoV microglia Middle East multi-organ system dysfunction nervous system Neurological complication Neurovascular Novel coronavirus pandemic Pathogenesis pathophysiology pro-inflammatory mediators Protein provide RAS renal respiratory Respiratory failure respiratory symptom SARS-CoV SARS-CoV-2 SARS-COV-2 infection secondary hemophagocytic lymphohistiocytosis signaling pathways stroke syndrome systemic hyper-inflammation Thrombotic events upregulation viral infection with COVID-19
[DOI] 10.1186/s12974-020-01896-0 PMC 바로가기 [Article Type] Review

Anti-plasmodial and anti-inflammatory activities of cyclotide-rich extract and fraction of Oldenlandia affinis (R. & S.) D.C. ( Rubiaceae )

올덴란디아 아피니스 (R. & S.) D.C. (꼭두서니과)의 사이클로타이드 풍부 추출물 및 분획의 항말라리아 및 항염증 활성이미지

Article

Published on 2017-09-012024-08-12
Journal: African Health Sciences [Category] 말라리아,

[키워드] Oldenlandia affinis Parasitemia Plasmodium berghei pro-inflammatory mediators Reactive oxygen/nitrogen species
[DOI] 10.4314/ahs.v17i3.26 PMC 바로가기 [Article Type] Article

Allicin enhances host pro-inflammatory immune responses and protects against acute murine malaria infection

알리신은 숙주 프로염증 면역 반응을 강화하고 급성 쥐 말라리아 감염으로부터 보호합니다.

Research

Published on 2012-08-082024-08-14
Journal: Malaria Journal [Category] 말라리아,

[키워드] dendritic cells macrophages Plasmodium yoelii pro-inflammatory mediators
[DOI] 10.1186/1475-2875-11-268 PMC 바로가기 [Article Type] Research