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Molecular diagnostics of SARS-CoV-2: Findings of an international survey

SARS-CoV-2의 분자 진단: 국제 조사 결과

Article

Published on 2022-06-012022-09-11
Journal: Clinica chimica acta; international journal of cli [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술,

[키워드] array Chain Reaction Chemistry clinical clinical chemistry Committee concerning Contact tracing contagious Containment country COVID COVID 19 COVID-19 pandemic Diagnosis diagnostic Diagnostic method diagnostic testing diagnostics Federation finding Genetic identify individual initiated International Laboratory laboratory procedures majority Medicine molecular molecular diagnostics NAAT participated Participation performed polymerase chain polymerase chain reaction processing Quality assurance quarantine question raise reported Reporting response reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 testing Sequencing Standardization survey the disease transcriptase Transmission variant variants
[DOI] 10.1016/j.cca.2022.04.007 PMC 바로가기 [Article Type] Article

[Nirmatrelvir plus ritonavir (Paxlovid) a potent SARS-CoV-2 3CLpro protease inhibitor combination]

[니르마트렐비르와 리토나비르(팍슬로비드)의 강력한 SARS-CoV-2 3CLpro 프로테아제 억제제 조합]

Review

Published on 2022-06-012022-09-11
Journal: Revista española de quimioterapia : publicación [Category] COVID19(2023년), SARS, 변종, 치료제,

Mining voices from self-expressed messages on social-media: Diagnostics of mental distress during COVID-19

Research article

Published on 2022-05-012022-10-05
Journal: Decision Support Systems [Category] 진단,

SARS-CoV-2 and wastewater: What does it mean for non-human primates?

SARS-CoV-2와 폐수: 인간이 아닌 영장류에게 어떤 의미가 있습니까?

Article

Published on 2022-05-012022-09-11
Journal: American journal of primatology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] accumulating acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected approach best changed Contact contracting the virus coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 disease disease transmission Evidence genetic susceptibility global pandemic help Human human pathogen Infection monkeys NHP NHPs non-human primate non-human primates Novel coronavirus novel coronavirus disease occurred one health Outbreaks pandemic Pathogens predict processing PROTECT recent researchers respiratory resulting risk risk of transmission SARS-CoV-2 severe acute respiratory syndrome Coronavirus Spread susceptibility susceptible synanthropic primates Transmission transmission of disease unique Viral Viral RNA virus wastewater zoonosis zoos
[DOI] 10.1002/ajp.23340 PMC 바로가기 [Article Type] Article

Combination of QSAR, molecular docking, molecular dynamic simulation and MM-PBSA: analogues of lopinavir and favipiravir as potential drug candidates against COVID-19

QSAR, 분자 도킹, 분자 동적 시뮬레이션 및 MM-PBSA의 조합: COVID-19에 대한 잠재적 약물 후보로서 로피나비르 및 파비피라비르의 유사체

Article

Published on 2022-05-012022-09-11
Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 치료제,

[키워드] Absorption active site analogue Analysis anti-viral drug Anti-viral drugs binding affinity candidate Candidates Compound COVID-19 COVID-19 infection COVID-19 infections demonstrated disease distribution docked complex docking drug candidate druggability effective enzyme Enzymes Favipiravir feature form identify IMPROVE in vitro inhibit Interaction less Lopinavir M pro metabolism Modification molecular molecular docking molecular dynamic simulations molecular dynamics Molecular dynamics simulation novel drug physicochemical polyprotein polyproteins processing protease QSAR Quantitative RdRP Replication residue RNA RNA polymerase RNA-dependent RNA polymerase SARS-CoV-2 selected shown significantly small molecule Small molecules Spread stable complex Toxicity trajectory translated Treatment Viral RNA viral RNA-dependent RNA polymerase
[DOI] 10.1080/07391102.2020.1850355 PMC 바로가기 [Article Type] Article

Computational investigation of binding of chloroquinone and hydroxychloroquinone against PLPro of SARS-CoV-2

SARS-CoV-2의 PLPro에 대한 클로로퀴논과 하이드록시클로로퀴논의 결합에 대한 전산 조사

Article

Published on 2022-04-012022-09-11
Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발, 치료제,

[키워드] Amino acid amino acid residue anticipated approved binding binding affinity carried Chloroquine cleavage complex conformational coronavirus SARS-CoV-2 COVID-19 docked drug target effective Epidemic FDA FDA approved drug HCQ Hydroxychloroquine identify Immune suppression inhibitor inhibitors of SARS-CoV-2 integrity involved MDs mechanism mechanism of action molecular molecular docking molecular dynamics Molecular dynamics simulation molecular dynamics simulations molecular target Mortality MPro novel Novel coronavirus pandemic Papain PLPro polyprotein processing protease repurposing rising SARS-CoV-2 SARS-CoV2 Simulation study the SARS-CoV-2 therapeutic interventions therapeutic targeting
[DOI] 10.1080/07391102.2020.1844804 PMC 바로가기 [Article Type] Article

The “LLQY” Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles

SARS-CoV-2 스파이크 단백질의 "LLQY" 모티프는 S가 바이러스 입자에 통합되는 데 영향을 줍니다.

Article

Published on 2022-03-232022-09-11
Journal: Journal of Virology [Category] SARS, 변종,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Affect Alter Amino acid amino acid residue amino acids antiviral drug antiviral drugs assembly biological significance Biosynthesis caused Cell culture cleavage cleavage site cleavage sites cleaved conformational conservation conserved Contact contribute coronavirus COVID-19 epidemic Critical demonstrated Effectiveness expressed glycoprotein hydrogen Hydrogen bond hydrogen bonds incorporation Infection intrachain junction key amino acid key amino acids less Lineage LLQY domain membrane fusion motif mutated Mutation Neutralizing antibodies Particle Prevent processing producer cell protease Protein protein synthesis protein synthesis and cleavage Pseudotyped virus pseudovirus pseudoviruses reduce residue S protein S1/S2 SARS-CoV-2 SARS-CoV-2 pseudoviruses SARS-CoV-2 variant SARS-CoV-2 variants sensitivity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike Spike protein stability subcellular localization synthesis the S protein the SARS-CoV-2 Transmission tyrosine Vaccines viral entry viral infection virus virus assembly Virus-like particle virus-like particles
[DOI] 10.1128/jvi.01897-21 PMC 바로가기 [Article Type] Article

Positive attitudes towards COVID-19 vaccines: A cross-country analysis

Research Article

Published on 2022-03-102022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

Identifying COVID-19 Outbreaks From Contact-Tracing Interview Forms for Public Health Departments: Development of a Natural Language Processing Pipeline

Original Paper

Published on 2022-03-082022-10-31
Journal: JMIR Public Health and Surveillance [Category] Coronavirus, MERS, SARS,

Effect of not vortexing nasopharyngeal and throat swabs on SARS-CoV-2 nucleic acid detection: A pilot study

SARS-CoV-2 핵산 검출에 대한 비인두 및 인후 면봉 검사의 효과: 파일럿 연구

Article

Published on 2022-03-012022-09-11
Journal: Journal of virological methods [Category] SARS, 치료기술,