Acute estradiol and progesterone therapy in hospitalised adults to reduce COVID-19 severity: a randomised control trial
Randomized Controlled Trial
[키워드] addition
Admission
adverse events
Anti-inflammatory
antibody production
approved drug
Biology
center
clinically
Corticosteroids
COVID-19
death
determine
disease severity
double blind
drug
Efficacy
Ethical approval
Ethics
evaluate
food
general endocrinology
Hospital stay
hospitalised
Hospitalised patients
HRT
HRT.
immune response
immune tolerance
include
Infectious diseases
Inflammatory biomarker
intramuscular
mechanical ventilation
Medicine
mitigate
New
New Orleans
Occurrence
Oestradiol
outcome
Participants
Patient
peer-reviewed
Phase 2
Placebo
placebo-controlled
primary endpoint
Primary outcome
progesterone
proportion
randomised
readmission
reduce
reducing
Result
Sample size
secondary
Sex
sex steroids &
Sponsor
Standard of care
steroid
subjects
submitted
the WHO
therapeutic option
therapy
Trial
university
USA
was obtained
WHO ordinal scale
[DOI] 10.1136/bmjopen-2021-053684 PMC 바로가기 [Article Type] Randomized Controlled Trial
[DOI] 10.1136/bmjopen-2021-053684 PMC 바로가기 [Article Type] Randomized Controlled Trial