Antiviral Plants from Marajó Island, Brazilian Amazon: A Narrative ReviewReview Published on 2022-02-242022-10-30 Journal: Molecules [Category] Coronavirus, [키워드] Abstract Amazon Region Antiviral article Brazil caused complementary Direct Diseases Epidemics EPO Europe Google Scholar HAV HBV Influenza INPI Intellectual island medicinal plants narrative organization Outbreaks over Pandemics Perspective pharmacological plant plants plants extract problem property reported resulting review SARS-CoV-2 Science Treatment United State Viral diseases virus Web of Science [DOI] 10.3390/molecules27051542 PMC 바로가기 [Article Type] Review
Redressing COVID-19 vaccine inequity amidst booster doses: charting a bold path for global health solidarity, together추가 접종으로 인한 COVID-19 백신 불평등 해소: 함께 글로벌 건강 연대를 위한 대담한 길을 개척하다Commentary Published on 2022-02-222022-09-11 Journal: Globalization and Health [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] access Activation addition adopted affected allocation approach booster booster dose component Connector country COVAX COVID-19 COVID-19 vaccine COVID-19 vaccine booster COVID-19 vaccines Critical distribution dose equity exacerbate Fair framework global health Health health equity health system help immunization initiative Intellectual intellectual property International Intervention involved mechanism minimum mitigate offer pandemic population at risk populations Prevent property receive risk scaled System Vaccine variants [DOI] 10.1186/s12992-022-00817-5 PMC 바로가기 [Article Type] Commentary
Immunomodulatory and Anti-Inflammatory Properties of Selenium-Containing Agents: Their Role in the Regulation of Defense Mechanisms against COVID-19셀레늄 함유 물질의 면역 조절 및 항염증 특성: COVID-19에 대한 방어 기제 조절에서의 역할Review Published on 2022-02-212022-09-10 Journal: International Journal of Molecular Sciences [Category] 치료제, [키워드] addition available data Complete Compound Coronavirus infection COVID-19 creating Defense defense mechanisms disease drug immune immune system information Laboratory mechanism methylseleninic acid methylselenocysteine pharmacological physical physical properties property Regulation role selenite Selenium selenium nanoparticles selenomethionine Selenoproteins sodium sodium selenite therapeutic these compounds Viral viral infections [DOI] 10.3390/ijms23042360 PMC 바로가기 [Article Type] Review
Design and Immunological Properties of the Novel Subunit Virus-like Vaccine against SARS-CoV-2Article Published on 2022-01-022022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Antigen betulin candidate vaccine COVID-19 COVID-19 pandemic domain effective effective vaccine elicited fused human IgG1 Fc Immunity immunization immunostimulatory Infection mice mimicking nanoparticle vaccine Neutralizing antibody response novel Particle Prevent property Protein RBD RBD-Fc-based vaccine RBD-specific antibodies Safe SARS-CoV-2 Spread subunit T cell Vaccine vaccine candidate Viral particles virus [DOI] 10.3390/vaccines10010069 PMC 바로가기 [Article Type] Article
Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcomeCOVID-19 환자 혈청의 비표적 대사체학은 심각성과 결과 모두의 잠재적인 예후 마커를 나타냅니다Original Article Published on 2021-12-202022-09-10 Journal: Metabolomics [Category] SARS, 바이오마커, 치료기술, [키워드] among others Analysis approach Bayesian Bayesian logistic regression model blind capture Cohort COVID-19 COVID-19 patient COVID-19 patient serum cross Deceased deoxycytidine diagnosis of COVID-19 discharged energy metabolism high resolution Hospital admission Host host inflammatory response host response include infected individual infected individuals Infection Kynurenine LC–MS/MS Orbitrap logistic regression model marker metabolism metabolite metabolites metabolomics Mild nucleic acid objective outcome Patient patient treatment Planning positive predict predicted Predictive predictor profile Prognostic marker property qualitative detection Result reveal ROC AUC ROC Curve selected serum severity statistical significance subset supplementary material Treatment UHPLC UHPLC-MS/MS uninfected control Untargeted metabolomics validation study Viral Viral load viral nucleic acid was performed [DOI] 10.1007/s11306-021-01859-3 PMC 바로가기 [Article Type] Original Article
Psychometric Properties of the Persian Version of the Center for Epidemiological Studies Depression Scale Among the Iranian Public People During COVID-19 PandemicPublic Health Published on 2021-12-142022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, SARS, [키워드] affects Analysis center conducted construct validity COVID-19 COVID-19 pandemic cross-sectional demonstrated Depression evaluate evaluated explained Exploratory factor analysis Factor indicated internal internal consistency Iran Persian version positive Prevalence property psychometric properties psychometric property Public reliability scale Sociodemographic characteristics total variance validation Version [DOI] 10.3389/fpubh.2021.728904 PMC 바로가기 [Article Type] Public Health
Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies코로나바이러스 결합 항체에서 시연된 컴퓨터 구조 모델링을 사용한 에피토프 프로파일링Research Article Published on 2021-12-132022-09-12 Journal: PLoS Computational Biology [Category] SARS, 진단, [키워드] 3D structure Algorithm Analysis antibodies antibody Antibody therapeutics approach approaches binding binding site Cluster Clustering complementary computational method conserved convergent evolution coronavirus database defined demonstrated detect domains engage epitope Epitopes Evolution experiment functional Genetic greater high accuracy identify identifying immune response immune responses immune system indicate Laboratory Lineage lineages molecular Mutation pathogen Pathogens population immunity predicted property sequence Space Specificities Strains Structure structure-function suggested therapeutic while yielding [DOI] 10.1371/journal.pcbi.1009675 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 Delta Variant Displays Moderate Resistance to Neutralizing Antibodies and Spike Protein Properties of Higher Soluble ACE2 Sensitivity, Enhanced Cleavage and Fusogenic ActivityArticle Published on 2021-12-112022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] ACE2 activity antibody antigenic distance AY.1 B.1.351 B.1.526 B.1.617 B.1.617 variants B.1.617.1 B.1.617.2 cleavage Complete contribute convalescent sera Delta delta variant display dominant effective enhanced exhibited greater India Infection Lineage mRNA mRNA-based vaccine neutralization neutralization resistance Neutralizing antibodies neutralizing antibody P.1 P681R property pseudovirus Pseudovirus neutralization assay pseudoviruses reduction reduction in resistance SARS-CoV-2 second wave sensitivity sera soluble ACE2 spike spike cleavage Spike protein Spread syncytia formation tested therapeutic variant variants [DOI] 10.3390/v13122485 PMC 바로가기 [Article Type] Article
Beneficial Properties of Bromelain브로멜라인의 유익한 특성Review Published on 2021-11-292022-09-10 Journal: Nutrients [Category] SARS, 변종, [키워드] acquisition activity Anti-inflammatory Anti-viral Blood coagulation Bromelain Cancer cardiovascular diseases Coagulation complementary concerning COVID-19 disease Diseases disorders Efficiency enzyme Escalation fibrinolysis help high availability Infectious diseases Inflammation mechanism object plants Post-COVID-19 patients Prevent progression property proteolytic proteolytic enzyme SARS-CoV-2 virus Spread sulfhydryl the SARS-CoV-2 virus therapy for COVID-19 Toxicity variant [DOI] 10.3390/nu13124313 PMC 바로가기 [Article Type] Review
Factor Structure and Psychometric Properties for the PTSD Checklist of Chinese Adolescents in the Closed Period after the COVID-19 OutbreakArticle Published on 2021-11-222022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] Adolescent adolescents Asymptomatic can be used caused CFA checklist China Chinese confirmatory factor analysis COVID-19 effective Epidemics Factor Factor analysis Gender groups Measurement invariance Measures mental health negatively affected participant Period property psychometric property PTSD public health reliability Structure suggested the epidemic were used [DOI] 10.3390/ijerph182212245 PMC 바로가기 [Article Type] Article