Quantitative CT comparison between COVID-19 and mycoplasma pneumonia suspected as COVID-19: a longitudinal studyCovid-19와 Mycoplasma pneumonia 간의 정량적 CT 비교 Covid-19로 의심되는 : 종단 연구Comparative Study Published on 2022-02-062022-09-01 Journal: BMC Medical Imaging [Category] Fulltext, MERS, 진단, [키워드] Algorithm analyzed automatically baseline C-reactive protein Chest computed tomography Computed tomography COVID-19 COVID-19 group curative curative effects declining deep learning Effect evaluate feature involved lobe lobes longitudinal change longitudinal changes lymphocyte Lymphocyte count lymphocyte counts material Mild Mycoplasma pneumonia no difference objective parameter Patient patients with COVID-19 peaked Pneumonia Prognosis pulmonary lesion pulmonary lesions Quantitative Quantitative CT reached Result significantly higher two group two groups Volume was used were assessed [DOI] 10.1186/s12880-022-00750-4 PMC 바로가기 [Article Type] Comparative Study
Effective deep learning approaches for predicting COVID-19 outcomes from chest computed tomography volumes흉부 컴퓨터 단층 촬영 부피에서 Covid-19 결과를 예측하기위한 효과적인 딥 러닝 접근Article Published on 2022-02-022022-09-01 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] aggregate Algorithm approach artificial intelligence AUC automated Chest computed tomography Chest CT Clinical data clinically Combination Computed tomography Computer science coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 patients COVID-19 pneumonia COVID-19 prognosis deep learning develop effective Evolution feature healthy IMPROVE joint lung Metadata Mortality Novel coronavirus novel coronavirus disease Numerous other viral pneumonia outcome pandemic participant Pneumonia predict problems Prognosis pulmonary lesion pulmonary lesions reduce risk stratification Transmission viral infection Viral pneumonia Volume volumetric [DOI] 10.1038/s41598-022-05532-0 PMC 바로가기 [Article Type] Article
Hamsters as a Model of Severe Acute Respiratory Syndrome Coronavirus-2중증 급성 호흡기 증후군 코로나바이러스-2의 모델로서의 햄스터Review Published on 2021-10-012022-09-11 Journal: Comparative medicine [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Affect age alveolar animal model animal models clinical disease Clinical outcome clinical outcomes Clinical sign Clinical signs contributed convalescent serum coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical death develop edema Effect Efficacy granulocyte hamster hamsters Health hemorrhage highlight human infection human infections humans Implications infected with SARS-CoV-2 Infection infiltration Injury inoculation interstitial lead lethargy lose weight Mesocricetus Model Mortality pandemic Pathogenesis Pneumonia preclinical studies preclinical study progression of disease pulmonary lesion pulmonary lesions Pulmonary pathology renal required respiratory Respiratory disease Respiratory system ruffled fur SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Severe infection severe infections Sex shown Spread Therapeutics Treatment vaccination virus variant virus variants weight while [DOI] 10.30802/AALAS-CM-21-000036 PMC 바로가기 [Article Type] Review
Longitudinal Radiological Findings in Patients With COVID-19 With Different Severities: From Onset to Long-Term Follow-Up After DischargeMedicine Published on 2021-09-212022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI abnormality absorbed age changed chest CT scan collected consolidation coronavirus disease COVID-19 COVID-19 cases Cox regression Cox regression analysis CT scan discharge discharged patient discharged patients Evolution Factor finding Follow-up GGO ground-glass opacity group help hospital Hospitalization Hospitalized identify independent indicated infected with COVID-19 Kaplan–Meier analysis Laboratory lactate dehydrogenase LDH lesion linear longitudinal manifestation morphology nine non-severe group Onset parenchymal parenchymal bands Participants Patient patients with COVID-19 Pneumonia predict Predictive Probability procalcitonin Prognosis pulmonary pulmonary lesion radiological radiological feature radiological finding reached Retrospective study risk severe group Severe patient severity stratified subpleural distribution the patient the WHO two group variable was performed was selected were used with COVID-19 [DOI] 10.3389/fmed.2021.711435 PMC 바로가기 [Article Type] Medicine
A 3D Hologram With Mixed Reality Techniques to Improve Understanding of Pulmonary Lesions Caused by COVID-19: Randomized Controlled TrialRandomized Controlled Trial Published on 2021-09-102022-10-04 Journal: Journal of Medical Internet Research [Category] SARS, 임상, [키워드] adverse impact age All participant can be used caused Chinese clinical Computed tomography Controlled COVID-19 COVID-19 outbreak determine diagnostic Efficiency global public health help hologram identify imaging IMPROVE independent index involved IQR lesion Likert scale load lung lung lesion median mixed reality objective pandemic participant Participants professionals pulmonary pulmonary lesion questionnaire radiologist Radiologists randomly divided REALITY Registration registry Result scored significantly higher significantly lower Space surgeon technique three group two group two groups understanding utility [DOI] 10.2196/24081 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues두 개의 원숭이 종에서 SARS-COV-2 감염의 급성기 후에는 폐 및 외부 조직에서 진행중인 바이러스 복제 및 병리의 징후와 관련이 있습니다.Article Published on 2021-08-232022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] activated acute phase animal models Computed tomography Conjunctiva consequence COVID-19 cynomolgus macaque cynomolgus macaques detectable Extrapulmonary extrapulmonary tissue feces heart histological Histopathology humans immune activation Infection investigated lesion lung lung tissue Lungs Lymph node lymph nodes macaque macaques Messenger RNA necropsy NHPs non-human primates nose nose and throat phase positron emission Positron emission tomography pulmonary pulmonary lesion pulmonary lesions respiratory respiratory tract rhesus salivary salivary gland SARS-CoV-2 SARS-COV-2 infection SIGN Specy tissue sample tissue samples tomography tracheobronchial tracheobronchial lymph nodes Viral Viral RNA virus replication [DOI] 10.3390/v13081673 PMC 바로가기 [Article Type] Article
Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patientsArticle Published on 2021-06-042022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 임상, 진단, 치료기술, 치료법, [키워드] Acute inflammation Anti-inflammatory CHRFAM7A Control controls correlated COVID-19 COVID-19 patient critical COVID-19 patient Critical disease CRP cytokine decreased expression dominant dominant negative expressed expressing expression healthy hypercytokinemia investigated leukocyte lymphopenia moderate pathway patients with COVID-19 plasma pro-inflammatory pulmonary lesion RNA expression SARS-COV-2 infection severity significantly lower subunit symptoms onset TNF viral infection Viral load Whole blood whole blood sample with COVID-19 [DOI] 10.1038/s41598-021-91417-7 PMC 바로가기 [Article Type] Article
Chest Computed Tomography (CT) as a Predictor of Clinical Course in Coronavirus Disease코로나바이러스 질병의 임상 경과 예측인자로서의 흉부 컴퓨터 단층촬영(CT)Article Published on 2021-06-032022-09-11 Journal: Medical science monitor : international medical jo [Category] SARS, 치료기술, [키워드] air bronchogram Air bubble analyzed bronchiolectasis bronchogram change character Chest CT chest imaging clinical Clinical data conducted consolidations correlation Course COVID-19 patients CT scan CT scans Diagnosis diagnostic discharged patient discharged patients disease course disease severity dominant Ground-glass opacities group Halo Halo sign Hospitalization Hospitalized imaging modality Infection infections interior Łańcut lesions lung Lung CT Lymphadenopathy non-survivor Non-survivors Occurrence Patient patients with SARS-CoV-2 pleural effusion pleural thickening Poland positive correlation Prognosis prognostic Prognostic value pulmonary lesion pulmonary lesions radiological feature retrospective retrospective review rRT-PCR SARS-COV-2 infection semi-quantitative severity statistically significant difference subpleural subsegmental the disease TSS utility vessel Warsaw was used [DOI] 10.12659/MSM.931285 PMC 바로가기 [Article Type] Article
Tocilizumab in patients with moderate or severe COVID-19: a randomized, controlled, open-label, multicenter trial중등도 또는 중증 COVID-19 환자의 토실리주맙: 무작위, 대조, 공개, 다기관 시험Randomized Controlled Trial Published on 2021-06-012022-09-12 Journal: Frontiers of medicine [Category] SARS, 임상, 진단, [키워드] 1:1 addition adverse event ameliorated assigned attenuate benefit Biomarker change Concentration conducted Control control group Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 patients cytokine Cytokine storm Effectiveness elevated hypoxia identify IL-6 levels IMPROVE Inflammation influences on Inhaled less Mild moderate disease Multicenter trial occurred Open-label outcome oxygen oxygen saturation Patient patients with moderate pulmonary lesion pulmonary lesions Randomized Randomly receive recipient reported severe adverse event Side effect standard care statistically significant Tocilizumab tocilizumab therapy Treatment virus load were recorded [DOI] 10.1007/s11684-020-0824-3 PMC 바로가기 [Article Type] Randomized Controlled Trial
Particulate matter exposure exacerbates susceptibility to SARS-CoV-2 infection in humanized ACE2 mice미립자 물질 노출은 인간화 ACE2 마우스에서 SARS-CoV-2 감염에 대한 감수성을 악화시킵니다Article Published on 2021-05-182022-09-11 Journal: Zoological research [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adsorption angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 caused Chinese coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 case COVID-19 cases death demonstrated English enzyme epidemic risk epidemiological epithelial cell epithelial cells exacerbate exacerbated expression expression level global pandemic hACE2 hACE2 mice. humanized indicate Infection Instillation Lungs Mask mechanism mice outbreak Particulate Particulate matter pulmonary lesion pulmonary lesions SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 entry factor SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 spike protein Serine severe acute respiratory syndrome Coronavirus significantly increased Spike protein Spread surpassed susceptibility the SARS-CoV-2 TMPRSS2 transmembrane serine protease transmembrane serine protease 2 viral replication [DOI] 10.24272/j.issn.2095-8137.2021.088 PMC 바로가기 [Article Type] Article