pulmonary lesion – Communicable Diseases Research

Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model

Article

Published on 2022-10-282022-11-15
Journal: Journal of Antimicrobial Chemotherapy [Category] COVID19(2023년), SARS, 진단, 치료제,

Novel application of [18F]DPA714 for visualizing the pulmonary inflammation process of SARS-CoV-2-infection in rhesus monkeys (Macaca mulatta)

Article

Published on 2022-09-012022-11-16
Journal: Nuclear medicine and biology [Category] COVID19(2023년), SARS, 치료기술,

Nebulization Therapy with Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes for COVID-19 Pneumonia

Clinical Trial

Published on 2022-08-012022-10-05
Journal: Stem cell reviews and reports [Category] COVID19(2023년), SARS, 임상,

Feasibility of a new lung ultrasound protocol to determine the extent of lung injury in COVID-19 pneumonia

Research article

Published on 2022-07-312022-10-05
Journal: Chest [Category] 임상, 진단,

Mortality Predictors in Severe SARS-CoV-2 Infection

Observational Study

Published on 2022-07-182022-10-05
Journal: Medicina [Category] COVID19(2023년), SARS, 임상,

[키워드] Admission age Algorithm changes in Cluster Clusters Community COVID-19 CT scan density clusters element evaluate evaluated Evolution form hemoglobin high mortality hospital hypoxic respiratory failure IMPROVE include increase interstitial lactate dehydrogenase lesions less lung lung involvement lung lesion Lymphocytes material Mortality Myoglobin non-survivor Non-survivors objective Observational cohort study oxygen flow PaO parameter parameters Patient performed Platelets Prediction score Predictive predictor Prognosis pulmonary involvement pulmonary lesion Quantitative quantitative evaluation radiological raising Regression model Result retrospective risk factor SARS-CoV-2 SARS-CoV-2 pneumonia semi-quantitative Sensitivity and specificity serum albumin serum creatinine Severe case severe COVID-19 Survivors
[DOI] 10.3390/medicina58070945 PMC 바로가기 [Article Type] Observational Study

Pulmonary lesions induced by SARS-CoV-2 infection in domestic cats

집고양이에서 SARS-CoV-2 감염으로 유발된 폐 병변

Article

Published on 2022-07-012022-09-11
Journal: Veterinary pathology [Category] COVID19(2023년), SARS, 치료기술,

[키워드] acute infection acute respiratory syndrome acute respiratory syndrome coronavirus affected alveolar alveolar fibrin B and T lymphocytes Blood blood vessel bronchiolar Bronchiolitis cat cats Chain Reaction consolidation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 disease DPI Endothelium epithelial expression fatal disease FIBRIN fibrosis histologic Histopathology hypertrophy immunohistochemistry in some individuals Infection interstitial pneumonia lesion limit of detection lung Lung disease lung lesion macrophages MHC II Microscopic Mild mild to moderate moderate occlusive patchy Patient Pneumonia polymerase chain polymerase chain reaction proliferation pulmonary pulmonary lesion pulmonary lesions quantitative polymerase chain reaction reactive respiratory signs reverse transcriptase SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA septal thickening severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 T lymphocytes type II pneumocytes vacuolar vacuolar degeneration Vasculitis vessel Viral load viral loads Viral RNA
[DOI] 10.1177/03009858211066840 PMC 바로가기 [Article Type] Article

Chronic lung lesions in COVID-19 survivors: predictive clinical model

COVID-19 생존자의 만성 폐 병변: 예측 임상 모델

Article

Published on 2022-06-132022-09-11
Journal: BMJ Open [Category] COVID19(2023년), SARS, 치료기술,

[키워드] Abnormalities abnormality architectural distortion automated Brazil bronchiectasis build Chest Chest CT chest imaging chest X-ray chronic Complete country COVID-19 COVID-19 infection CXR detect Dyspnoea e parameters Early detection eligible forced vital capacity FVC Ground-glass opacities hospital hospital discharge hospitalised joint lung lung lesion lung lesions Medical Research Council mMRC outcome oximetry parameter parenchymal Patient Predictive prospective cohort study protocol Pulmonary function pulmonary involvement pulmonary lesion pulmonary lesions respiratory medicine (see thoracic medicine) reticulation RT-PCR SARS-COV-2 infection SARS-CoV-2-infected patient sensitivity specificity spirometry survivor Thoracic traction bronchiectasis vital capacity were used
[DOI] 10.1136/bmjopen-2021-059110 PMC 바로가기 [Article Type] Article

SARS CoV-2 (Delta Variant) Infection Kinetics and Immunopathogenesis in Domestic Cats

SARS CoV-2(Delta Variant) 감염 역학 및 국내 고양이의 면역 병인 발생

Article

Published on 2022-06-012022-09-11
Journal: Viruses [Category] COVID19(2023년), SARS, 변종,

[키워드] ACE2-expressing cell ACE2-expressing cells acute COVID-19 acute infection animal model animal models B.1.617.2 chemokine chemokine signaling circulating Clinical sign Cluster correlated correlation COVID-19 disease COVID-19 disease course Critical cytokine receptor Delta delta variant develop differentially expressed gene Differentially expressed genes disease Disease progression disease transmission Divergence domestic cats dose downstream dysregulated evaluate feline ferrets flexible genetic modification help highlight Host hub genes identify immunopathology include Infection Infectious virus Inflammatory inflammatory pathways inoculated Interaction interactions intranasally Kinetics lesion lesions limitation lung lung tissue Lungs Mild nasal network analysis non-human primates pathology pathway peribronchial Pneumocytes Post-infection Prevent progression pulmonary inflammation pulmonary lesion pulmonary lesions Respiratory disease RNA sequencing SARS CoV SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants secretion significantly Spread target therapeutic timepoints transgenic mice translational upregulation variant Vascular endothelium Vasculitis Viral antigen Viral protein virus WGCNA wild-type SARS-CoV-2
[DOI] 10.3390/v14061207 PMC 바로가기 [Article Type] Article

Nebulized exosomes derived from allogenic adipose tissue mesenchymal stromal cells in patients with severe COVID-19: a pilot study

Clinical Trial

Published on 2022-05-262022-10-04
Journal: Stem Cell Research & Therapy [Category] 임상,

[키워드] adipose administration adverse event adverse events assigned chest imaging Clinical characteristics clinical study COVID-19 COVID-19 patient COVID-19 patients D-dimer daily dose demographic data dose Efficacy Efficiency enrolled event Evidence Exosome Exosomes Extracellular vesicles feasible females Hospital admission IL-6 incidence inhalation interquartile range IQR laboratory result Lymphocyte count male median median age median time Mesenchymal stromal cell. MSC nebulized onset of symptom Patient patients patients with COVID-19 pilot study Pneumonia Primary outcome pulmonary lesion receive safety profile Serious Adverse Events serum Seven severe COVID-19 single-arm slight increase stromal cell supported tested tissue Toxicity Treatment Trial Vesicle vesicles Wuhan, China
[DOI] 10.1186/s13287-022-02900-5 PMC 바로가기 [Article Type] Clinical Trial

The Impact of SARS-CoV-2 Infection on Premature Birth-Our Experience as COVID Center

Observational Study

Published on 2022-04-252022-10-05
Journal: Medicina [Category] COVID19(2023년), SARS, 임상,