The INCH-trial: a multicenter randomized controlled trial comparing short- and long-term outcomes of open and laparoscopic surgery for incisional hernia repairarticle Published on 2023-10-092024-09-05 Journal: Surgical endoscopy [Category] update2024, [키워드] abdominal wall Incisional hernia Laparoscopic repair Open repair Quality of life RCT [DOI] 10.1007/s00464-023-10446-7 PMC 바로가기 [Article Type] article
Probiotic vs. placebo and metformin: probiotic dietary intervention in polycystic ovary syndrome – A randomized controlled trialarticle Published on 2023-04-172024-09-05 Journal: BMC Endocrine Disorders [Category] update2024, [키워드] metformin PCOS Probiotic RCT [DOI] 10.1186/s12902-023-01294-6 PMC 바로가기 [Article Type] article
The Michigan Genetic Hereditary Testing (MiGHT) study’s innovative approaches to promote uptake of clinical genetic testing among cancer patients: a study protocol for a 3-arm randomized controlled trialarticle Published on 2023-02-102024-09-05 Journal: Trials [Category] update2024, [키워드] Cancer eHealth Genetic counseling Genetic testing Motivational interviewing RCT [DOI] 10.1186/s13063-023-07125-2 PMC 바로가기 [Article Type] article
Safety and feasibility of faecal microbiota transplant for major depressive disorder: study protocol for a pilot randomised controlled trialarticle Published on 2023-01-092024-09-05 Journal: Pilot and Feasibility Studies [Category] update2024, [키워드] Depression Faecal microbiota transplantation major depressive disorder Mental disorder mental health Microbiome mood disorders neuroscience psychiatry RCT [DOI] 10.1186/s40814-023-01235-z PMC 바로가기 [Article Type] article
Assessing the reporting quality of randomized controlled trials on COVID-19 vaccines: a systematic reviewCOVID-19 백신에 대한 무작위 대조 시험의 보고 품질 평가: 체계적인 검토Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] 임상, [키워드] adverse effect Analysis analysis of variance Assessing CONSORT CONSORT statement controlled trials COVID-19 COVID-19 vaccine COVID-19 vaccines criteria current database effective evaluated Evidence groups independent indicate indicated median Mortality no significant difference predicted Randomized Randomized controlled trial Randomized controlled trials RCT RCTs reported Reporting Reporting quality review Standard systematic review Univariate analysis variance variety [DOI] 10.1080/21645515.2022.2031453 PMC 바로가기 [Article Type] Article
Effect of colchicine on the outcomes of patients with COVID-19: a systematic review and meta-analysis of randomised controlled trialsCOVID-19 환자의 결과에 대한 콜히친의 영향: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-12-012022-09-11 Journal: Annals of Medicine [Category] 임상, [키워드] 95% CI addition adverse event adverse events Clinical efficacy clinical outcomes ClinicalTrials Cochrane Library Colchicine control group COVID-19 database diarrhoea Effect higher risk hospital Hospital stay improve clinical outcome mean difference mechanical ventilation Meta-analysis Mortality no significant difference non-invasive ventilation not reduce Odds ratio outcome OVID Patient patients with COVID-19 Placebo placebos randomised controlled trial RCT RCTs receiving risk SARS-CoV-2 searched significant difference significantly higher standard treatment study group Support systematic review the study group Treatment Web of Science [DOI] 10.1080/07853890.2022.2096919 PMC 바로가기 [Article Type] Meta-Analysis
Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trialArticle Published on 2022-11-012022-11-15 Journal: Intensive care medicine [Category] Fulltext, MERS, 바이오마커, [키워드] ABO-compatible convalescent plasma Adaptive platform trial Adults Analysis assigned Biomarker Biomarkers chemokines community-acquired pneumonia convalescent plasma Convalescent plasma therapy coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critically ill critically ill patients Cytokines difference effector immune responses elevated endothelial explain heterogeneous homogeneous Hypothesis immunologically immunotherapies Inflammation IQR median multifactorial organ support outcome outcomes patients Population precision medicine Prevalence Randomized randomized clinical trial RCT RCTs REMAP-CAP reported secondary analysis Subphenotypes. tested therapy treatment effect Treatment response usual care with COVID-19 [DOI] 10.1007/s00134-022-06869-w PMC 바로가기
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trialsArticle Published on 2022-11-012022-11-15 Journal: European Journal of Clinical Pharmacology [Category] SARS, 치료제, [키워드] 95% CI 95% confidence interval addition anti-inflammatory effect antiparasitic antiviral activity blinded clinical benefit continuous variable COVID-19 D-dimer D-dimer level death dichotomous variable Disease progression Effect effect size Efficacy and safety element eligibility enrolled Evidence Frequency ICU admission in vitro individual Inflammation Invasive mechanical ventilation lactate dehydrogenase LDH magnitude Meta-analysis Mild moderate Moderate COVID-19 nitazoxanide no difference Patient patients peer-reviewed performed Placebo placebo-controlled positive positive RT-PCR Primary outcome randomized clinical trial RCT RCTs receiving reducing reduction in reported risk SARS-CoV-2 SARS-COV-2 infection secondary outcome serum biomarker SMD standardized mean difference systematic review tested to define treat treated Viral load WBC were used White blood cell with COVID-19 [DOI] 10.1007/s00228-022-03380-5 PMC 바로가기
Acupuncture for dry eye disease after recovery from COVID-19: A protocol for systematic review and meta-analysisArticle Published on 2022-10-282022-11-16 Journal: Medicine [Category] meta-analysis, [키워드] acupuncture Chinese clinical decision Cochrane Library coronavirus disease COVID-19 COVID-19 infection COVID-19 patient database disease Diseases Dry eye Efficacy and safety evaluate evaluated exclusion criteria Guidance Inclusion Infrastructure Meta-analysis ophthalmic Patient peer-reviewed Prevalence protocol Randomized controlled trial RCT review risk Science screened Stata Symptom systematic review technology Treatment was performed was used Web of Science [DOI] 10.1097/MD.0000000000031234 PMC 바로가기
Comparative effectiveness of neutralising monoclonal antibodies in high risk COVID-19 patients: a Bayesian network meta-analysisArticle Published on 2022-10-202022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), meta-analysis, SARS, 변종, 진단, [키워드] absolute reduction article baseline Bayesian comparable Comparative COVID-19 Effect effective Effectiveness Efficacy Evidence expected generalisability healthcare high risk hospitalisation ICU admission identify individual infected individual infected with SARS-CoV-2 invasive ventilation moderate monoclonal antibody Mortality network Network meta-analysis neutralising outcome Pairwise comparison patient population patients patients treated Placebo predict Rate RCT reaction reduce mortality reducing reduction in relative risk risk reduction serious AE severe COVID-19 statistically significant reduction systematic review therapy treatment effect vaccination variant [DOI] 10.1038/s41598-022-22431-6 PMC 바로가기