Expanding the antiviral potential of the mosquito lipid-transfer protein AEG12 against SARS-CoV-2 using hydrophobic antiviral ligandsArticle Published on 2022-10-012022-11-15 Journal: Febs Letters [Category] COVID19(2023년), SARS, 치료제, [키워드] Antiviral antiviral activity antiviral therapeutics bind Cell complexes Compound cytotoxicity drug delivery enveloped virus fatty Fatty acid hydrophobic inhibitors Ligand ligands lipid-binding protein mechanism membrane membrane disruption. membranes modulated neutralize Protein replaced resulting SARS-CoV-2 Therapeutic compounds unsaturated viruses [DOI] 10.1002/1873-3468.14456 PMC 바로가기
Neutralization effect of plasma from vaccinated COVID-19 convalescents on SARS-CoV-2 Omicron variantsArticle Published on 2022-09-292022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] average B.1.1.529 B.1.617.2 caused convalescent convalescent COVID-19 patients convalescent individual convalescent individuals coronavirus COVID-19 death Delta delta variant determine escaped global pandemic Infection neutralization neutralization activity neutralize Neutralizing activity Neutralizing antibodies not neutralize not significant omicron Patient performed plasma plasma sample pre-vaccination Pseudovirus neutralization assay raise reduction replaced reported SARS-CoV-2 sera shown significant difference significantly three groups Vaccine variant [DOI] 10.3389/fimmu.2022.975533 PMC 바로가기
SARS-CoV-2 variant spike and accessory gene mutations alter pathogenesisArticle Published on 2022-09-132022-11-16 Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 변종, [키워드] accessory gene Accessory genes accessory protein acute respiratory syndrome Affect Alter both virus cells characterized clinical disease clone contribute coronavirus COVID-19 pandemic Deletion driven by Effect ENhance evade Genome Host in vitro in vivo innate immune mouse Mutation pandemic Pathogenesis persists Protein public health crisis Receptor binding replaced Replication replication of SARS-CoV-2 SARS-CoV-2 SARS-CoV-2 pathogenesis SARS-CoV-2 variant shown Signaling spike mutation Spread the spike protein Transmission Vaccine vaccine responses variant variant spike Viral variants virus viruses [DOI] 10.1073/pnas.2204717119 PMC 바로가기
Immune response to SARS-CoV-2 Omicron variant in patients and vaccinees following homologous and heterologous vaccinationsArticle Published on 2022-09-022022-11-16 Journal: Communications Biology [Category] SARS, 변종, [키워드] antibody Antibody Response booster dose Course COVID-19 COVID-19 patient cross-protection delta variant drastic reduction elicited ENhance evaluate Heterologous highest homologous Immunity mRNA vaccine Mutation natural infection neutralization capacity neutralize omicron Patient regimen replaced SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus serum sample survivor susceptibility tested the spike protein vaccinated individual vaccination Vaccine vaccinee variant wild-type virus [DOI] 10.1038/s42003-022-03849-0 PMC 바로가기
Identifying behavior of long-distance virus transmission and mitigation performance from a COVID-19 outbreak of a daycare center어린이집 코로나19 발생에 따른 장거리 바이러스 전파거동 및 완화성능 파악Article Published on 2022-09-012022-09-11 Journal: Environmental research [Category] COVID19(2023년), SARS, 치료기술, [키워드] Air purifier airflow applied Behavior can not Care children close contact conducted contribute COVID-19 COVID-19 outbreak Critical Daycare center experiment field Field investigation flush Flush-out fomite identifying infected with SARS-CoV-2 Long-distance transmission. measure outbreak Particle Prevent reduce replaced reported researcher risk Spread transfer Transmission Ventilation virus virus spread virus transmission [DOI] 10.1016/j.envres.2022.113318 PMC 바로가기 [Article Type] Article
Covid-19, an unfinished storyMini review Published on 2022-09-012022-10-05 Journal: La Presse Médicale [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] activities acute respiratory distress age amplitude bat coronavirus Beta Betacoronavirus caused China Cluster Comorbidities compulsory vaccination condition confirmed case coronavirus COVID-19 Critical cross deaths degree Delta detect development drug effective Efficacy epidemic waves epidemiological surveillance evade Face mask FIVE form Gamma Genome genomic Health highly pathogenic homogeneity Host Human immune response Immunity incidence rate include Inflammatory Innovation intensive care Measures Messenger RNA mild infection Moderna mRNA vaccine multiorgan failure nucleotides occupancy rate omicron Oxygen therapy pandemic Patient Pfizer-BioNTech Pneumonia preventing the transmission progressed Protective replaced RNA SARS-CoV-2 SARS-CoV-2 vaccine Sequencing severity syndrome the WHO thromboembolic complications Vaccine Vaccines variant variants variants of concern viral invasion VoC WHO World Health Organization [DOI] 10.1016/j.lpm.2022.104131 [Article Type] Mini review
X-ray image based COVID-19 detection using evolutionary deep learning approachResearch article Published on 2022-09-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 변종, 치료기술, [키워드] Accuracy Algorithm approach automatically boundary Chest Chest X-ray images Classifier CNN complex Comprehensive Convolutional neural network coronavirus coronavirus disease COVID-19 COVID-19 disease deep learning Deep neuroevolution learning detect detectable develop diagnose effective help image classification IMPROVE K-nearest neighbor classifier labeling MONITOR radiological radiologist replaced significantly more time-consuming Trial X-ray [DOI] 10.1016/j.eswa.2022.116942 [Article Type] Research article
Replication of SARS-CoV-2 Omicron BA.2 variant in ex vivo cultures of the human upper and lower respiratory tractArticle Published on 2022-09-012022-11-16 Journal: EBioMedicine [Category] SARS, 변종, [키워드] airway antibody bronchial Bronchial tissue characterized China clinical manifestation Committee comparable Culture Delta delta variant disease severity Ex vivo explain explained Hong Kong human lung tissue immune evasion Infectious disease Lower respiratory tract lung lung tissue nasal nasal tissue observation omicron Omicron BA.2 parenchymal pathogenicity Patient Region replaced replicated Replication respiratory tissue SARS-CoV-2 strain Strains supported tested tissue Transmissibility Transmission university variant virus viruses wild-type wild-type virus [DOI] 10.1016/j.ebiom.2022.104232 PMC 바로가기
Differentiation of SARS-CoV-2 Variants Using RT-qPCRs by Targeting Recurrent Mutation Sites: A Diagnostic Laboratory Experience from Multi-Center Regional Study, August 2020-December 2021, Poland재발성 돌연변이 부위를 표적으로 하는 RT-qPCR을 사용한 SARS-CoV-2 변이체의 분화: 다중 센터 지역 연구의 진단 실험실 경험, 2020년 8월-2021년 12월, 폴란드Multicenter Study Published on 2022-08-202022-09-11 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 치료기술, 치료제, [키워드] Alpha Alpha variant assigned Beta can be used changed collected conducted COVID-19 Delta delta variant diagnostics differentiation distribution epidemiological epidemiological surveillance experience Kappa Mutation mutations National omicron Omicron variants Poland proportion Rapid Recurrent Regional replaced REPLACED BY RT-qPCR RT-qPCR variant differentiation SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants screened specimen Surveillance targeting tested time interval variant variants virus [DOI] 10.3390/ijms23169416 PMC 바로가기 [Article Type] Multicenter Study
Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines포괄적인 백신 패널에 의해 유도된 오미크론 스파이크 기능 및 중화 활성Article Published on 2022-08-192022-09-11 Journal: Science (New York, N.y.) [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin angiotensin-converting enzyme 2 Antibody titers binding booster breadth coronavirus dominant elicited evade evaluated homologous or heterologous Infection leads Neutralizing activity Neutralizing antibody response Neutralizing antibody titer neutralizing antibody titers omicron plasma polyclonal Prevalence reduced replaced respiratory SARS-CoV-2 sequence Seven severe acute respiratory syndrome Coronavirus severe disease spike mutation Vaccine variant virus Wuhan-Hu-1 [DOI] 10.1126/science.abq0203 PMC 바로가기 [Article Type] Article