Economic Burden of SARS-CoV-2 Patients with Multi-Morbidity: A Systematic Review ProtocolReview Published on 2022-10-132023-07-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), [키워드] cardio/cerebrovascular Comorbidity COVID-19 diabetes Economic burden hypertension respiratory diseases [DOI] 10.3390/ijerph192013157 PMC 바로가기 [Article Type] Review
The suboptimal fibrinolytic response in COVID-19 is dictated by high PAI-1Article Published on 2022-10-012022-11-16 Journal: Journal of thrombosis and haemostasis : JTH [Category] 변종, [키워드] 113 patient analyzed attenuate clot cofactor Complication confocal microscopy correlated COVID-19 COVID-19 disease COVID-19 sample disease drugs dysregulation elevated ELISA faster fiber FIBRIN fibrinolysis fibrinolytic fibrinolytic system groups healthy control healthy controls highlight Hospitalized inhibitor Non-COVID-19 PAI-1 Patient patients with COVID-19 plasma profile prognostic Prospective Study quantified respiratory diseases respiratory infection reveal severe COVID-19 disease severity significantly substrates thrombotic complication tissue plasminogen activator treat variant Vitronectin with COVID-19 [DOI] 10.1111/jth.15806 PMC 바로가기
The Variation of Transcriptomic Perturbations is Associated with the Development and Progression of Various DiseasesArticle Published on 2022-09-262022-11-16 Journal: Disease Markers [Category] 유전자 메커니즘, [키워드] activities AIDS AIDS patient Algorithm analyzed applied association atrophic gastritis cardiovascular diseases caused cellular chronic obstructive clinical implication clinically controls COPD correlated correlation COVID-19 patient deficiency defined development digestive disease Disease diagnosis Disease progression Diseases Ejection fraction Endocrine diseases expiratory expression greater Health status heterogeneity ICU immune Infection intensive care investigated involved Kidney diseases liver diseases LVEF malaria mechanical ventilatory support negative correlation Neurological disorders non-ICU patients pathway patients Perturbation presymptomatic Prognosis pulmonary disease pulmonary tuberculosis Regulation respiratory diseases severity significantly syndrome the disease Therapies transcriptome datasets transcriptomic transcriptomic data treated upregulated upregulation Variation variety ventricular Viral load Volume [DOI] 10.1155/2022/2148627 PMC 바로가기
Clinical trial and detection of SARS-CoV-2 by a commercial breath analysis test based on Terahertz technologyArticle Published on 2022-09-202022-11-15 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] Algorithm Analysis Asymptomatic Brazil breath clinical Compound correlation COVID-19 diagnosing Diagnostic method evaluate gold standard Health Infection International Local National non-infected noninvasive organic Pandemics Patient Public Rapid required respiratory diseases RT-qPCR SARS-CoV-2 SARS-CoV-2 positivity screening method sensitivity social isolation specificity statistical tested the SARS-CoV-2 threat Trial virus [DOI] 10.1371/journal.pone.0273506 PMC 바로가기
Protective role of zinc in the pathogenesis of respiratory diseases Reviews Published on 2022-08-182022-10-05 Journal: European journal of clinical nutrition [Category] 치료제, [키워드] Analysis Anti-inflammatory antioxidant Antiviral Apoptosis cancer cell disease Effect highlight immune In vitro studies Inflammation inhibit lipid metabolism Lung diseases Lungs morbidity and mortality oxidative stress Pathogenesis Perspective Protective effects protective mechanism provide regulate Regulation Research respiratory Respiratory disease respiratory diseases subjects therapy variety [DOI] 10.1038/s41430-022-01191-6 [Article Type] Reviews
Epigenetic mechanisms regulate sex-specific bias in disease manifestations후성 유전적 메커니즘은 질병 발현에서 성별에 따른 편향을 조절합니다Review Published on 2022-08-012022-09-11 Journal: Journal of Molecular Medicine (Berlin, Germany) [Category] 유전자 메커니즘, [키워드] affecting Anatomy Autoimmune disorders Cancer change chromosome Clinical outcome clinical study COVID-19 COVID-19 infection differential expression disease disease manifestation disease onset Diseases Effect Epigenetic epigenetic modification epigenetics exhibit explained expression fibrosis Genes Genetic Genetic and epigenetic changes Hormones immune response immune responses immune system implicated inactivation infections input involved Liver fibrosis mechanism Neuropsychiatric Neuropsychiatric diseases progression recent regulate Respiratory disease respiratory diseases response to therapy responsible Sex Sex bias Sex chromosome sex hormone Sex hormones susceptibility therapeutic targets therapy underlying disease X chromosome X-inactivation X-linked X-linked gene X-linked genes. [DOI] 10.1007/s00109-022-02227-x PMC 바로가기 [Article Type] Review
Human Lung Fibroblasts Exhibit Induced Inflammation Memory via Increased IL6 Gene Expression and Release인간 폐 섬유아세포는 증가된 IL6 유전자 발현 및 방출을 통해 유도된 염증 기억을 나타냅니다Article Published on 2022-07-222022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ACTA2 affected Analysis ANOVA Cell cell line cell lines chronic respiratory disease chronic respiratory diseases Col1a1 contribute COVID-19 determine determined by downregulated ELISA fibroblast fibroblasts fibrosis followed by Gene Expression Human human lung IL1B IL2 IL6 IL8 Immunity Increased induced Inflammatory inflammatory memory Inflammatory response inhibition inhibitor interleukin-6 investigated involved lung memory Mmp8 mRNA expression multiple groups NF-κB not affect pathway Pathways Poly (I:C) POSTN predict qRT-PCR Release respiratory diseases respond SARS-CoV-2 SARS-CoV-2 spike protein significantly significantly increased Simultaneous Simultaneous treatment Spike protein statistical significance subsequent TGFB1 TLR3 TNFα trained immunity treated Treatment two-way ANOVA viral infection was determined were measured were used Withdrawal [DOI] 10.3389/fimmu.2022.921728 PMC 바로가기 [Article Type] Article
Making cough count in tuberculosis care Reviews Published on 2022-07-062022-10-05 Journal: Communications Medicine [Category] 진단, [키워드] Acoustic Biomarker Care cascade Clinical management condition cough detect disease Epidemiology Health IMPROVE increasingly Making management outcome Patient public health respiratory diseases Stage Support Tuberculosis while [DOI] 10.1038/s43856-022-00149-w [Article Type] Reviews
Rational development of a combined mRNA vaccine against COVID-19 and influenza Research Published on 2022-07-012022-10-05 Journal: NPJ Vaccines [Category] 임상, 진단, 치료기술, 치료법, [키워드] Antigen Cellular immune response characterized clinical outcomes COVID-19 COVID-19 pandemic Delta demonstrated dose elicited ENCODE Final H1N1 highlight IAV immunization Influenza influenza A influenza A virus mice morbidity and mortality mRNA vaccine platform Protective antibody RBD respiratory diseases robust S protein SARS-CoV-2 Seasonal influenza the receptor-binding domain the SARS-CoV-2 Vaccine vaccine platform variants virus [DOI] 10.1038/s41541-022-00478-w [Article Type] Research
First COVID-19 lockdown resulted in most respiratory viruses disappearing among hospitalised children, with the exception of rhinoviruses첫 번째 COVID-19 잠금으로 인해 병원에 입원한 어린이들 사이에서 리노바이러스를 제외한 대부분의 호흡기 바이러스가 사라졌습니다.Article Published on 2022-07-012022-09-11 Journal: Acta paediatrica (Oslo, Norway : 1992) [Category] 치료기술, [키워드] acute communicable diseases Admission carried cause childhood children communicable communicable diseases COVID-19 COVID-19 pandemic effective emergency room evaluated Face masks Hospital admission Hospital admissions hospitalisation hospitalisations hospitalised Italian Italy less lockdown measure nasal pandemic reduced reducing remained Respiratory disease respiratory diseases respiratory infections respiratory syncytial virus respiratory tract infection respiratory virus respiratory viruses rhinovirus rhinoviruses Rome RSV significantly lower social distancing tested university virus [DOI] 10.1111/apa.16326 PMC 바로가기 [Article Type] Article