ARDS in the time of corona: context and perspectiveArticle Published on 2022-10-012022-11-16 Journal: American journal of physiology. Lung cellular and [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory distress ARDS COVID-19 disease endothelial infections mutants Perspective Respiratory failure severe COVID-19 syndrome therapeutic therapy to define Treatment Ventilator-induced lung injury ventilator-induced lung injury. [DOI] 10.1152/ajplung.00432.2021 PMC 바로가기
Extracorporeal membrane oxygenation for respiratory failure in phases of COVID-19 variantsArticle Published on 2022-10-012022-11-16 Journal: Journal of cardiac surgery [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory distress acute respiratory distress syndrome, extracorporeal membrane oxygenation affected age average circulatory support. coronavirus coronavirus disease COVID-19 Delta delta variant demographics discharge ECMO Extracorporeal extracorporeal membrane oxygenation Healthcare system Hispanic hospital ICU in-hospital mortality intensive care Intervention laboratory-confirmed SARS-CoV-2 infection later phase LOS male membrane Most patient Mutation no significant difference outcome Oxygenation pandemic Patient patients who survived predominant Prevalence random Respiratory failure SARS-CoV-2 Severe respiratory distress Support supported survival syndrome variant variants Viral genome sequencing virus white [DOI] 10.1111/jocs.16563 PMC 바로가기
Real-life Evidence of Lower Lung Virulence in COVID-19 Inpatients Infected with SARS-CoV-2 Omicron Variant Compared to Wild-Type and Delta SARS-CoV-2 PneumoniaArticle Published on 2022-10-012022-11-16 Journal: Lung [Category] COVID19(2023년), SARS, 변종, [키워드] adult subject ambient animal model ARDS better respiratory function blood gas analysis Comorbidities consolidation COVID-19 Delta described evidence of explain hospital Hospitalization Immunity in vitro Infection Inpatient Italy less Lineage Lower lower mortality lower risk lung parenchyma observation omicron other variant Pneumonia preliminary finding replication capacity respiratory airway Respiratory failure SARS-CoV-2 severe respiratory failure Turin variants of concern virulence virulence. wild type [DOI] 10.1007/s00408-022-00566-7 PMC 바로가기
The current status of thrombosis and anticoagulation therapy in patients with COVID-19 in Japan: From the CLOT-COVID studyObservational Study Published on 2022-10-012022-10-05 Journal: Journal of cardiology [Category] COVID19(2023년), SARS, 임상, [키워드] Anticoagulant Anticoagulants anticoagulation Asian bleeding Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection diagnosed with COVID-19 died disease dose enrolled hospital Hospitalization hospitalized patient incidence Japan Major management Mild Moderate COVID-19 multicenter cohort study occurred Patient patients with COVID-19 pharmacological Pneumonia polymerase chain positive proportion Respiratory failure retrospective severe COVID-19 severity the patient therapy Thromboprophylaxis thrombosis thrombosis. unmet need Venous Thromboembolism with COVID-19 [DOI] 10.1016/j.jjcc.2022.03.015 PMC 바로가기 [Article Type] Observational Study
Sex-dependent characteristics of Neuro-Long-COVID: Data from a dedicated neurology ambulatory serviceShort communication Published on 2022-10-012022-10-05 Journal: Journal of the neurological sciences [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute COVID-19 acute phase response acute respiratory symptom age approach brain fog Characteristics Clinical data Cluster collected conducted demographic Dyspnea feature female headache immune response individuals Infection joint large sample long-COVID male males neurological no significant difference no significant differences offer PACS Pain palpitation Pathogenesis Patient Prevalence Respiratory failure Retrospective study SARS-CoV-2 Sex Sex difference significant difference Standard deviation subgroup analysis Support Symptom Symptoms the mean two groups Ventilation while [DOI] 10.1016/j.jns.2022.120355 [Article Type] Short communication
Comparative Upper Respiratory Tract Transcriptomic Profiling Reveals a Potential Role of Early Activation of Interferon Pathway in Severe COVID-19Article Published on 2022-10-012022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제, [키워드] Acute respiratory infection Comparative Coronavirus disease 2019 COVID-19 COVID-19 negative COVID-19 patient COVID-19 patients death driving evaluated Genes Host transcriptional response host-pathogen interactions IFN-I IFN-I response Inflammation initial symptom interferon involved ISG ISGs lung mechanism Mild OAS Potential Profiling progression respiratory Respiratory failure RNA-Seq RNA-sequencing role SARS-CoV-2 severe COVID-19 patient severe COVID-19 patients severe symptom stimulated symptomatic patient the disease tract type I interferon upper upper respiratory tract upregulated viral infection Viral infection. Viral load [DOI] 10.3390/v14102182 PMC 바로가기
Characteristics and outcomes of SARS-COV 2 critically ill patients after emergence of the variant of concern 20H/501Y.V2: A comparative cohort studyArticle Published on 2022-09-302022-11-16 Journal: Medicine [Category] SARS, 변종, [키워드] 24 hours 95 % CI 95% CI 95% confidence interval absence Admission Analysis change Characteristics cohort of patient cohort study Complete coronavirus 2 Critical care Critically ill patient demographic data dominant expected Fever forest higher risk ICU immunological improvement increased risk Indian Ocean indicated intensive care Invasive mechanical ventilation island less Lineage management Mayotte Mortality outcome outcomes Patient patients performed respiratory Respiratory failure SARS-CoV-2 second wave severe patients severity suggested survival Transmissibility unique VAP variant Ventilator-associated pneumonia Viral genome sequencing VoC [DOI] 10.1097/MD.0000000000030816 PMC 바로가기
Human genetic basis of severe or critical illness in COVID-19Article Published on 2022-09-202022-11-16 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome affecting association Asymptomatic base caused contribute coronavirus COVID-19 Critical Critical illness death determinant disease disease severity enhanced Enzymes Factor Genetic Genetic variation genetic. Host Human human leukocyte antigen immune component indicated Interaction Interleukins loci mild infection morbidity and mortality multi-organ dysfunction outcome Precision preventive measure Respiratory failure SARS-CoV-2 SARS-CoV-2 receptor Serine severity of COVID-19 Toll-like receptor transmembrane [DOI] 10.3389/fcimb.2022.963239 PMC 바로가기
Usefulness of fibrosis-4 (FIB-4) score and metabolic alterations in the prediction of SARS-CoV-2 severityArticle Published on 2022-09-012023-07-09 Journal: Internal and Emergency Medicine [Category] COVID19(2023년), [키워드] FIB-4 hepatic steatosis Metabolic burden Respiratory failure type 2 diabetes. [DOI] 10.1007/s11739-022-03000-1 PMC 바로가기
Network analysis for elucidating the mechanisms of Shenfu injection in preventing and treating COVID-19 combined with heart failureResearch article Published on 2022-09-012022-10-05 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, [키워드] acting acute respiratory syndrome Analysis approach biological process biological processe caused cell differentiation China Chinese components Compound compound screening coronavirus COVID-19 COVID-19 case Critical cytokine signaling Cytoscape Cytoscape software Diagnosis drug-likeness Effectiveness enrichment analysis Evidence heart failure Hemostasis identify IL-17 immune system indicated Infection Inflammatory response injection involved KEGG pathway Kyoto Lung injury mechanism Medicine National Health Commission network network analysis novel coronavirus disease objective overlapped Pathway analysis Pathway enrichment analysis Pathways patients with COVID-19 pharmacological mechanism Pharmacological mechanisms Pharmacology progression protein-protein interaction regulated Respiratory failure Result SARS-CoV-2 Shenfu injection signaling pathway Stage suggested syndrome System target targets TCM Th17 therapeutic therapy Traditional treat treating COVID-19 Treatment was used [DOI] 10.1016/j.compbiomed.2022.105845 [Article Type] Research article