SAR-CoV-2 – Page 2 – Communicable Diseases Research

A Review of the Presence of SARS-CoV-2 in Wastewater: Transmission Risks in Mexico

폐수 내 SARS-CoV-2 존재에 대한 검토: 멕시코의 전파 위험

Review

Published on 2022-07-082022-09-11
Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 치료기술,

Identification of repurposing therapeutics toward SARS-CoV-2 main protease by virtual screening

가상 스크리닝을 통한 SARS-CoV-2 주요 프로테아제에 대한 용도 변경 치료제 식별

Article

Published on 2022-06-302022-09-11
Journal: PLoS ONE [Category] COVID19(2023년), SARS, 신약개발, 치료제,

[키워드] 3CLpro addition applied binding binding energy carried cause Combination common drug coronavirus disease Coronavirus disease 2019 criteria Critical crystal structure drug effective effective drug effective drugs Efficiency enzyme FDA-approved drug FDA-approved drugs feature FIVE global pandemic HBD IC50 identification in viral inhibit inhibit SARS-CoV-2 inhibitor inhibitors Lapatinib molecular molecular docking molecular dynamics molecular dynamics simulations pandemic performed protease provide residue SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 main protease selected these compounds viral replication Virtual screening
[DOI] 10.1371/journal.pone.0269563 PMC 바로가기 [Article Type] Article

Positivity rates of SAR-CoV-2 infection in orthodontic patients at the orthodontic clinic, University of Illinois Chicago

University of Illinois Chicago 교정 진료소 교정 환자의 SAR-CoV-2 감염 양성률

Article

Published on 2022-06-232022-09-11
Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술,

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

리소자임은 인간 각막 상피 세포의 중증 급성 호흡기 증후군 코로나바이러스 2 감염 및 염증으로부터 보호합니다

Article

Published on 2022-06-012022-09-11
Journal: Investigative ophthalmology & visual science [Category] COVID19(2023년), SARS, 치료기술, 치료제,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Against analyzed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 cell entry Cell toxicity characterized Corneal coronavirus coronavirus 2 Effect entry of SARS-CoV-2 enzyme epithelial cell epithelial cells expressed expression Human IL-6 Infection Inflammatory cytokine Inflammatory response luciferase lysozyme MCP-1 Pathogens pro-inflammatory molecule pro-inflammatory molecules proinflammatory molecule proinflammatory molecules PROTECT protective effect Protective effects pseudotyped respiratory robust RT-PCR SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection secretion Serine Spike protein Spike proteins stimulated suggested susceptibility tears TMPRSS2 TNF-α Toxicity transmembrane serine protease was measured was tested western blotting
[DOI] 10.1167/iovs.63.6.16 PMC 바로가기 [Article Type] Article

A Case of COVID-19-Induced Delayed-Onset Myocarditis

코로나19 유발 지연성 심근염 1예

Case Reports

Published on 2022-05-102022-09-11
Journal: The American journal of case reports [Category] COVID19(2023년), SARS, 치료기술,

[키워드] acute respiratory distress acute respiratory distress syndrome adverse impact Affect affected ailment cardiovascular system cause of death caused center characterized city Complete complete recovery Complication coronavirus COVID-19 COVID-19 infection criteria Critical death in COVID-19 determine diagnosing difficulty breathing discharged disorder Dyspnea Early detection Fever General population heart failure heart muscle Ho Chi Minh Hospitalized include Lake magnetic resonance imaging medications Medicines MRI myocarditis nasal noninvasive organ outcomes oxygen Oxygen treatment pandemic PCR positive Probability respiratory distress Respiratory system SAR-CoV-2 Support syndrome the patient therapy treated Treatment university were used
[DOI] 10.12659/AJCR.935577 PMC 바로가기 [Article Type] Case Reports

Rapid and Accurate Identification of SARS-CoV-2 Variants Using Real Time PCR Assays

Real Time PCR 어세이를 사용한 SARS-CoV-2 변이체의 빠르고 정확한 식별

Article

Published on 2022-05-102022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] Coronavirus, COVID19(2023년), SARS, 변종, 치료기술, 치료제,

[키워드] allele Alpha B.1.1.7 B.1.351 B.1.617.2 Beta blinded Combination correlated COVID-19 COVID-19 pandemic Delta delta variant Diagnosis diagnostic testing disease severity E484K effort Epidemiology evade Gamma Genomic surveillance genotyping help host immunity identification Laboratory lack Lineage management Mutation N501Y omicron P.1 P681R Patient Patient management PCR positive primer Rapid real-time RT-PCR resource reverse transcription-PCR routine diagnostic testing RT-PCR S982A SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants screened Sequencing specimen specimens spike gene Surveillance susceptibility tested the SARS-CoV-2 Therapeutics These data time Transmissibility variant variants Viral variants WGS while whole-genome sequencing
[DOI] 10.3389/fcimb.2022.894613 PMC 바로가기 [Article Type] Article

Identification of a novel SARS-CoV-2 variant with a truncated protein in ORF8 gene by next generation sequencing

차세대 시퀀싱에 의한 ORF8 유전자의 절단된 단백질을 갖는 신규 SARS-CoV-2 변이체 식별

Article

Published on 2022-03-172022-09-11
Journal: Scientific Reports [Category] SARS, 변종, 유전자 메커니즘,

Emergency SARS-CoV-2 Variants of Concern: Novel Multiplex Real-Time RT-PCR Assay for Rapid Detection and Surveillance

긴급 SARS-CoV-2 우려 변종: 신속한 탐지 및 감시를 위한 새로운 멀티플렉스 실시간 RT-PCR 분석

Research Article

Published on 2022-02-232022-09-10
Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 치료기술, 치료제,

[키워드] ΔHV 69/70 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha Analysis applied assays B.1.1.7 B.1.351 B.1.617.2 Beta caused circulating clinical sample clinical samples coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 patient Critical cross-reactivity Delta detect detection diagnostic difficulty E484K E484R effective Efficiency Emergency ENhance Epidemic epidemiological epidemiological surveillance Evolution feasibility FIVE Gamma gold gold standard Government infection control issue K417N K417T L452R Laboratory lineages Local local government multiplex Multiplex PCR Mutation mutations N501Y novel omicron outbreak P.1 P681H P681R PCR PCR assay Previous studies previous study primer probe probes provided public health measures Rapid real-time reverse transcriptase real-time RT-PCR receptor Receptor-binding domain reduced reported respiratory reverse transcriptase RT-PCR S gene SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Sequencing severe acute respiratory syndrome Coronavirus specificity Spike protein Spread Surveillance susceptibility Taiwan targets the receptor-binding domain the spike protein time intervals Transmissibility treatment regimens understanding upper respiratory Vaccine Vaccines variant variants variants of concern variants of SARS-CoV-2 viruses VoC VOC genotyping VOCs whole-genome sequencing
[DOI] 10.1128/spectrum.02513-21 PMC 바로가기 [Article Type] Research Article

Estimating SARS-CoV-2 Seroprevalence in Canadian Blood Donors, April 2020 to March 2021: Improving Accuracy with Multiple Assays

2020년 4월부터 2021년 3월까지 캐나다 헌혈자의 SARS-CoV-2 혈청유병률 추정: 다중 분석으로 정확도 개선

Research Article

Published on 2022-02-232022-09-10
Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 진단, 치료법,

[키워드] 95% CI Abbott advent Analysis Antibody Response antibody tests approach Architect assays blood donor Blood donors can be used Chicago IL cross-sectional cross-sectional design cross-sectional study diagnostic diagnostic testing disease Epidemics evaluate evaluated fatality full-length spike glycoprotein gold gold standard house identify IgG IgG antibodies IgG ELISA Improving indicate Infection infections laboratory assay laboratory assays latent class latent class analysis less Multiple nucleocapsid nucleocapsid antigen occur Pandemics Prevalence provide public health random RBD Receptor binding domain recognizing reference standard Reference standards repeated resulting SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody Sensitivity and specificity sera serological data serological studies SEROLOGICAL STUDY Seropositivity Seroprevalence seroreversion silent spike spike glycoprotein Support Surveillance vaccination
[DOI] 10.1128/spectrum.02563-21 PMC 바로가기 [Article Type] Research Article

A Trans-Governmental Collaboration to Independently Evaluate SARS-CoV-2 Serology Assays

Article

Published on 2022-02-232023-06-19
Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS,

[키워드] Emergency use authorization evaluation panel SAR-CoV-2 serology assay.
[DOI] 10.1128/spectrum.01564-21 PMC 바로가기