Preliminary Genomic Analysis of the Omicron Variants of SARS-CoV-2 in Central India During the third wave of the COVID-19 PandemicResearch article Published on 2022-08-012022-10-05 Journal: Archives of medical research [Category] SARS, 변종, 유전자 메커니즘, 치료기술, 치료제, [키워드] Antiviral approach Beta bioinformatics clade COVID-19 Delta determine evolutionary relationship Gamma Health Illumina immune evasion India isolate Lineage machine Medicines Mutation Next-generation sequencing non-structural protein omicron Omicron variant other variants Phylogenetic Phylogenetic tree positive prevalent Result RNA SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 variant SARS-CoV-2 variants SARS‐CoV‐2 sequence sequenced South Africa specimen spike Toxicity Transmissibility unique UPGMA Vaccine-induced immunity variant variants Variation virus VOCs [DOI] 10.1016/j.arcmed.2022.08.006 [Article Type] Research article
Immune Escape Associated with RBD Omicron Mutations and SARS-CoV-2 Evolution DynamicsRBD 오미크론 돌연변이 및 SARS-CoV-2 진화 역학과 관련된 면역 탈출Review Published on 2022-07-222022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] absence Affect appearance bioinformatics COVID-19 COVID-19 pandemic described Dynamics escape Evolution explained Features Genome high affinity high mutation rate Host immune Immune escape Lineage Mutation mutation rate natural immunity omicron pathogenicity Protein RBD RBD mutations receptor SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 strains serotype Spike protein the Spike therapeutic therapeutic agent therapeutic agents Transmissibility Vaccine Vaccine development Vaccine development. variant virus virus [DOI] 10.3390/v14081603 PMC 바로가기 [Article Type] Review
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution바이러스 진화 중 SARS-CoV-2 수용체 결합 도메인의 돌연변이 제약 조건 이동Article Published on 2022-07-222022-09-11 Journal: Science (New York, N.y.) [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 ACE2 binding acute respiratory syndrome acute respiratory syndrome coronavirus Affect Alpha Amino acid angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibodies antibody Beta coronavirus Delta domain Effect epistasis Eta Evolution example facilitate Interpretation modulating Mutation N501Y occur omicron performed phenomenon RBD RBDs receptor Recognition respiratory SARS-CoV-2 SARS-CoV-2 evolution severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike receptor-binding domain subsequent Substitution substitutions the SARS-CoV-2 variant variants viral evolution Wuhan-Hu-1 [DOI] 10.1126/science.abo7896 PMC 바로가기 [Article Type] Article
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection Amendments and Corrections Published on 2022-07-212022-10-05 Journal: Nature [Category] 유전자 메커니즘, 진단, [키워드] chronic infection SARS-CoV-2 evolution Treatment [DOI] 10.1038/s41586-022-05104-2 [Article Type] Amendments and Corrections
Evolutionary insight into the emergence of SARS-CoV-2 variants of concern우려의 SARS-CoV-2 변종 출현에 대한 진화론적 통찰력Article Published on 2022-07-012022-09-11 Journal: Nature Medicine [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] antibody chronic infection Mutation reveal SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 variant Transmissibility variants variants of concern virus [DOI] 10.1038/s41591-022-01892-2 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Whole-Genome Sequencing by Ion S5 Technology-Challenges, Protocol Optimization and Success Rates for Different StrainsIon S5 기술에 의한 SARS-CoV-2 전체 게놈 시퀀싱 - 다양한 균주에 대한 과제, 프로토콜 최적화 및 성공률Article Published on 2022-06-062022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Amplicon arise assigned cDNA Concentration construction COVID-19 COVID-19 pandemic demonstrated diagnostics Effectiveness Emergency genomic data idea immunization Ion less library library preparation lineages Modification molecular Molecular epidemiology mRNA mRNA or viral vector vaccines Mutation Next-generation sequencing NGS optimization Panel Patient Poland produced protocol Public public health emergency Rate Real-time PCR required RT-PCR SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 lineage SARS-CoV-2 sequencing Scientific community Sequencing strain Support Surveillance Thermo Fisher Scientific variant variants variants of concern Viral Viral load Viral RNA Viral vector vaccines whole-genome whole-genome sequencing Whole-genome sequencing. [DOI] 10.3390/v14061230 PMC 바로가기 [Article Type] Article
Structural diversity of the SARS-CoV-2 Omicron spikeSARS-CoV-2 오미크론 스파이크의 구조적 다양성Article Published on 2022-06-022022-09-11 Journal: Molecular Cell [Category] COVID19(2023년), SARS, 변종, [키워드] affecting Analysis changes in communication conformational conformational change Critical cryo Cryo-electron microscopy cryo-EM structure cryo-EM structures Crystallography Delta delta variant determine domain dominant electron microscopy epitope fusion peptide immune immune evasion Impact interprotomer communication intraprotomer communication Mutation Neutralizing Neutralizing antibodies neutralizing antibody omicron Omicron spike peptide RBD Receptor-binding domain SARS-CoV-2 evolution spike Spike protein the SARS-CoV-2 Transmissibility variant vector analysis. virus transmissibility X-ray X-ray crystallography [DOI] 10.1016/j.molcel.2022.03.028 PMC 바로가기 [Article Type] Article
Co-infection with SARS-CoV-2 Omicron and Delta variants revealed by genomic surveillance게놈 감시로 밝혀진 SARS-CoV-2 오미크론 및 델타 변이체와의 동시 감염Article Published on 2022-05-182022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] Amplicon Chronic kidney disease Co-infection Community Delta delta variant detect determine diagnostic epidemiologically events Frequency genomic genomic data Genomic surveillance Haemodialysis highlight Kidney disease omicron pathway Patient Population precursor quantified Rapid recombination event required Respiratory samples SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 variants Sequencing severe COVID-19 subpopulation subpopulations Surveillance the SARS-CoV-2 variant variants of concern variants of SARS-CoV-2 virus [DOI] 10.1038/s41467-022-30518-x PMC 바로가기 [Article Type] Article
Genetic and Structural Analysis of SARS-CoV-2 Spike Protein for Universal Epitope Selection보편적 에피토프 선택을 위한 SARS-CoV-2 스파이크 단백질의 유전 및 구조 분석Article Published on 2022-05-032022-09-11 Journal: Molecular Biology and Evolution [Category] COVID19(2023년), SARS, 변종, [키워드] Accessibility addition Amino acid amino acid sequence approach Comparative conserved coronavirus coronavirus diseases COVID-19 determine epitope Epitopes explain Genetic genome replication immunogenic molecular dynamics Molecular dynamics simulation molecular dynamics simulations mutated mutational rate observation omicron Omicron variant performed predicted Protein SARS-CoV SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 variant SARS-CoV-2 variants Selection sequence Sequence analysis spike translation Universal utility vaccine candidate vaccine candidates Vaccine development variant variants variants of SARS-CoV-2 variants. [DOI] 10.1093/molbev/msac091 PMC 바로가기 [Article Type] Article
Inter-domain communication in SARS-CoV-2 spike proteins controls protease-triggered cell entrySARS-CoV-2 스파이크 단백질의 도메인 간 통신은 프로테아제에 의해 유발된 세포 진입을 제어합니다Article Published on 2022-05-032022-09-11 Journal: Cell Reports [Category] COVID19(2023년), SARS, 변종, [키워드] adaptive addition antibody Antibody neutralization cell entry changes changes in cleavage Control coronavirus CP: Microbiology domain driving facilitate fusion activation hypersensitive identify Infection Inter-domain mechanism membrane membrane fusion Microbiology Mutagenesis neutralization NTD NTDs Particle proteolysis proteolytic activation provide recognize restriction SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 spike protein SARS-CoV-2 virus SARS-CoV-2 virus particle selective Spike protein Spike proteins subsequent Transmission Variability variant variants variants of concern Variation virus virus virus entry Virus evolution Virus neutralization virus particles virus variation. VoC [DOI] 10.1016/j.celrep.2022.110786 PMC 바로가기 [Article Type] Article