Evaluation of the Relationship between Clonal Hematopoiesis and Severe COVID-19 Disease in Rhesus Macaques
Conference abstract
[키워드] Acquired
advanced age
age
Analysis
Asymptomatic
autologous
Autopsy
BAL
benefit
Blood
clinical manifestation
clinical symptom
clinically
co-morbidities
cohort study
Concentration
Control
control group
controls
COVID-19
COVID-19 disease
detectable
develop
died
disease
Evidence
expand
Factor
Genes
group
hallmark
Hematopoiesis
Human
Hyperinflammatory
IL-6
IL-6 level
IL-8
Infection
Inflammation
inoculated
Laboratory
LOF
loss of function
lung tissue
macaque
MCP-1
Mild
MIP-1b
Multiorgan
mutant
Mutation
occur
pathophysiological
pathophysiology
phenotype
progenitor cell
relationship
reported
Respiratory failure
Respiratory samples
rhesus macaque
risk
risk factor
robust
Sample size
SARS-CoV infection
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 RNA
sera
severe COVID-19
severe COVID-19 disease
severe COVID-19 illness
significant difference
somatic mutation
suggested
Symptom
TET2
the median
therapeutic approaches
therapy
Vaccine development
Viral antigen
[DOI] 10.1182/blood-2021-152628 [Article Type] Conference abstract
[DOI] 10.1182/blood-2021-152628 [Article Type] Conference abstract