Aberrant Fibrin Clot Structure Visualized Ex Vivo in Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 InfectionObservational Study Published on 2022-06-012022-10-05 Journal: Critical Care Medicine [Category] 임상, [키워드] acute respiratory syndrome age anticoagulation assessment Biomarkers body mass index buffer clot Coagulation Cohort Comorbidities contribute coronavirus coronavirus 2 COVID-19 COVID-19 patient Critically ill patient cross-sectional determine died failure fibrin clot fluorescent functional Gender ICU ICU admission ICU patient Ill implication Infection interquartile range Laboratory measurement median microthrombi Mortality outcome Patient patients with COVID-19 patients without COVID-19 plasma positively correlated reported required respiratory Sepsis SOFA SOFA score Structure was collected was used widespread with COVID-19 [DOI] 10.1097/CCM.0000000000005465 PMC 바로가기 [Article Type] Observational Study
Clinical and laboratory predictors at ICU admission affecting course of illness and mortality rates in a tertiary COVID-19 center3차 COVID-19 센터의 질병 경과 및 사망률에 영향을 미치는 ICU 입원 시 임상 및 실험실 예측 변수Observational Study Published on 2022-05-012022-09-11 Journal: Heart & lung : the journal of critical care [Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료기술, [키워드] Admission affected affecting age Analysis analyzed applied Arterial hypertension bacterial superinfections baseline clinical clinical feature Clinical features Cohort Comorbidities congestive heart failure Course COVID-19 COVID-19 patient COVID-19 patients Critical care Critically ill critically ill COVID-19 patients Croatia CRP determine Factor Features hospital hypertension ICU ICU admission IL-6 increase Inflammatory biomarker Invasive mechanical ventilation Laboratory laboratory parameter Laboratory parameters Length Mortality mortality rate mortality rates mortality risk multivariate adjustment outcome PaO predict predictor primary endpoint primary endpoints Regression model retrospective risk factor Risk factors Serum ferritin SOFA SOFA score survival survival analysis survival rates Survivors therapeutic intervention therapeutic interventions treated Trial utility [DOI] 10.1016/j.hrtlng.2022.01.013 PMC 바로가기 [Article Type] Observational Study
The early use of sepsis scores to predict respiratory failure and mortality in non-ICU patients with COVID-19Case Reports Published on 2022-05-012022-10-05 Journal: Revista clínica española [Category] 임상, [키워드] adults hospitalized assessment coronavirus COVID-19 COVID-19 patients cutoff point death defined died discrimination Early warning scores English failure Fallo respiratorio Hospitalized ICU intensive care unit mechanical ventilation Mortality non-ICU patient occurred PaO Patient patients with COVID-19 predict qSOFA respiratory Respiratory failure Retrospective study SARS-CoV-2 score Sepsis Sepsis-Related Organ Failure Assessment. SOFA Spanish with COVID-19 [DOI] 10.1016/j.rceng.2020.10.004 PMC 바로가기 [Article Type] Case Reports
Comparison of clinical characteristics and outcomes of COVID-19 patients undergoing early versus late intubation from initial hospital admission: A systematic review and meta-analysisReview article Published on 2022-05-012022-10-05 Journal: Respiratory investigation [Category] COVID19(2023년), SARS, 바이오마커, 임상, [키워드] 95% confidence interval age Alter body mass index Clinical characteristics Clinical outcome Cochrane Library cohort study comparable coronavirus disease COVID-19 COVID-19 pandemic COVID-19 patient database defined delayed intubation determine diabetes Early intubation early phase explain First wave hospital Hospital admission hospital mortality rate IMV in-hospital mortality initial intubation Invasive mechanical ventilation Late intubation mechanical ventilation Meta-analysis mortality rate no significant difference Odds ratio Organ failure outcome pandemic Patient Primary outcome renal replacement therapy required Research Result RRT SARS-CoV-2 searched Sex significantly SOFA SOFA score systematic review Therapies Web of Science while [DOI] 10.1016/j.resinv.2022.02.007 [Article Type] Review article
Interim analysis of the COSA (COVID-19 patients treated with the Seraph® 100 Microbind® Affinity filter) registryCOSA(Seraph® 100 Microbind® Affinity 필터로 치료한 코로나19 환자) 레지스트리의 중간 분석Article Published on 2022-03-252022-09-11 Journal: Nephrology, dialysis, transplantation : official p [Category] SARS, 치료법, [키워드] 30-day mortality rate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adverse adverse events adverse outcome adverse outcomes affinity Analysis assessment authorization average bacterial superinfection Blood Characteristics clinical Complete coronavirus coronavirus disease Coronavirus disease 2019 correlated country COVID COVID-19 COVID-19 patient COVID-19 patients Cox regression demonstrated Device died drug Efficacy Emergency Emergency use authorization evaluate event extracorporeal treatment failure failure rate FDA ferritin ferritin levels Filter Follow-up food Food and Drug Administration hospital ICU ICU admission ICU patient ICU Patients intensive care Interim kidney median Mortality mortality rate multivariate multivariate Cox regression non-ICU non-ICU patients nucleocapsid outcome parameter Pathogens Patient patients patients treated performed predicted Premature reduction registry removal replacement therapy reported representing SARS-CoV-2 SARS-CoV-2 virus Seraph severe acute respiratory syndrome Coronavirus severe coronavirus disease shown SOFA SOFA scores Symptoms the SARS-CoV-2 virus therapy treated Treatment treatment for COVID-19 treatment of COVID-19 Viraemia Viral load viruses were excluded while [DOI] 10.1093/ndt/gfab347 PMC 바로가기 [Article Type] Article
Assessment of a cellular host response test to risk-stratify suspected COVID-19 patients in the Emergency Department settingClinical Trial Published on 2022-03-162022-10-04 Journal: PLoS ONE [Category] 임상, [키워드] Admission assessment Blood CBC cellular clinical outcomes clinician COVID-19 COVID-19 pandemic COVID-19 patient Department Emergency green had more hospital host response index initial Interpretation ISI median mortalities Mortality pandemic Patient patients positive presenting prospective cohort required respiratory infection respiratory symptom risk risk stratification SARS-CoV-2 single-center study SOFA Standard of care study enrollment tested vital signs [DOI] 10.1371/journal.pone.0264220 PMC 바로가기 [Article Type] Clinical Trial
The Effects of Enteral Nutrition in Critically Ill Patients with COVID-19: A Systematic Review and Meta-AnalysisReview Published on 2022-03-072022-10-31 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] 95% CI Analysis article articles assessment conducted COVID-19 Critically ill Critically ill patient database days on mechanical ventilation delayed enteral nutrition early enteral nutrition Effect effective Enteral enteral nutrition evaluate the effect failure gastrointestinal intolerance Google Scholar Hospital stay ICU Ill Inflammation intestinal mucosa Length of hospital stay Malnutrition Meta-analysis Mortality no significant difference not significant nutrition on mechanical ventilation parenteral nutrition Patient patients patients with COVID-19 PICO Protein reduce reduced reducing reduction in reductions in relative review risk searched significant increase significantly SOFA Stress Support systematic review with COVID-19 [DOI] 10.3390/nu14051120 PMC 바로가기 [Article Type] Review
High serum nitrates levels in non-survivor COVID-19 patientsObservational Study Published on 2022-03-012022-10-05 Journal: Medicina intensiva [Category] SARS, 바이오마커, 임상, [키워드] 30-Day mortality ABC APACHE II association AUC Blood Canary Island carried Coronavirus 2019 coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Determination English healthy subjects hospital ICU ICU admission ICUs intensive care unit Kaplan-Meier Kaplan-Meier analysis Logistic regression analysis Mortalidad Mortality mortality rate Nitrate nitrite Niveles séricos de nitratos no difference non-survivor observation Patient patients Prognosis Pronóstico prospectivo serum Serum nitrate levels Serum nitrate levels. SOFA SOFA score Spain Spanish surviving patient variable [DOI] 10.1016/j.medine.2020.10.007 PMC 바로가기 [Article Type] Observational Study
Continuous Renal Replacement Therapy With oXiris Filter May Not be an Effective Resolution to Alleviate Cytokine Release Syndrome in Non-AKI Patients With Severe and Critical COVID-19Pharmacology Published on 2022-02-042022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Admission alanine aminotransferase ALB albumin alleviate ALT Aspartate aminotransferase AST C-reactive protein circulating cytokine clinical collected Concentration Continuous Continuous renal replacement therapy control group coronavirus disease COVID-19 Critical CRP CRRT CRS Cytokine release syndrome Cytokine storm demographic determine fibrinogen Filter hospital Hospitalization hyper inflammation ICU IFN-γ IL-10 IL-2 IL-4 IL-6 individual inflammatory chemokines intervention group IRB lymphocyte Lymphocyte count medical records medical system neutrophil no significant difference non-acute kidney injury Organ failure oXiris filter Patient Platelet proportion Protein random number table randomly divided Release renal replacement therapy replacement Resolution SARS-COV-2 infection sensitivity serum creatinine severe and critical COVID-19 severity of COVID-19 significantly significantly higher significantly lower SOFA strained TNF-α total bilirubin treated Treatment two groups WBC White blood cell [DOI] 10.3389/fphar.2022.817793 PMC 바로가기 [Article Type] Pharmacology
Effect of COVID 19 pneumonia on hyperglycemia: Is it different from non COVID pneumonia?Observational Study Published on 2022-02-012022-10-05 Journal: Diabetes & metabolic syndrome [Category] COVID19(2023년), SARS, 임상, [키워드] Admission age Comorbidities Comorbidity correlated Corticosteroids COVID COVID 19 COVID pneumonia COVID-19 Critical Critical illness demonstrated diabete diabetes Diabetic Diagnosis Diseases dose Effect Factors Glucose glucose control glycemic control greater Healthcare system Hospital stay hospitalized patient ICU insulin lower mortality multicenter Non-COVID-19 not correlated outcomes Patient patients with COVID-19 performed Pneumonia protocol receive Regression model retrospective cohort significant interaction SOFA steroid time with COVID-19 [DOI] 10.1016/j.dsx.2022.102407 PMC 바로가기 [Article Type] Observational Study