SOFA
[대역어] 소파
[용어속성] Term
[용어속성] Term
Exploring the pathogen diagnosis and prognostic factors of severe COVID-19 using metagenomic next-generation sequencing: A retrospective study
Original Paper
[키워드] APACHCE-II
conventional pathogen test
konvencionalni test na patogene
mNGS
Pathogens
patogeni
SOFA
[DOI] 10.5937/jomb0-49102 PMC 바로가기 [Article Type] Original Paper
[DOI] 10.5937/jomb0-49102 PMC 바로가기 [Article Type] Original Paper
Clinical prediction models in hospitalized patients with COVID-19: A multicenter cohort study
Article
[키워드] Accuracy
acute COVID-19
Admission
age
APACHE II
asymptomatic infection
calculated
Care
clinical
Clinical decision rules
COVID-19
COVID-GRAM
Critical
CURB-65
death
died
Hospital stay
Hospitalized
hospitalized patient
IMPROVE
In-hospital death
independent predictor
intubation
Italian
majority
Mortality
multicenter cohort study
Negative predictive value
novel coronavirus disease
outbreak
PaO2/FiO2 ratio
Patient
patients with COVID-19
Pneumonia
Positive predictive value
predict
predictor
Prognosis
prognostic
risk
SARS-CoV-2
Sepsis
severe respiratory failure
SOFA
[DOI] 10.1016/j.rmed.2022.106954 PMC 바로가기
[DOI] 10.1016/j.rmed.2022.106954 PMC 바로가기
Identification of COVID-19 patients at risk of hospital admission and mortality: a European multicentre retrospective analysis of mid-regional pro-adrenomedullin
Observational Study
[키워드] age
Analysis
assessment
Bacterial infections
Classifier
collected
Combination
COVID-19 patient
CRP
death
demographics
Department
discharge
Emergency
emergency department
Europe
European
examined
failure
hospital
Hospital admission
hospitalisation
identification
identify
IMPROVE
in viral
increased risk
infected with SARS-CoV-2
Infection
Inflammatory biomarker
International
LDH
mid-regional pro-adrenomedullin
Mortality
MR-proADM
multicenter
multicentre
Organ failure
outcome
Patient
patients
performed
presenting
previous study
primary endpoint
prognostic
Prognostic factor
random
Retrospective analysis
risk
RT-qPCR
Safe
SARS-CoV-2
SARS-COV-2 infection
secondary care
Sepsis
Septic shock
SOFA
SOFA score
the patient
Treatment
utility
was performed
[DOI] 10.1186/s12931-022-02151-1 PMC 바로가기 [Article Type] Observational Study
[DOI] 10.1186/s12931-022-02151-1 PMC 바로가기 [Article Type] Observational Study
IgG Against Human Betacoronavirus Spike Proteins Correlates With SARS-CoV-2 Anti-Spike IgG Responses and COVID-19 Disease Severity
Article
[키워드] acute respiratory syndrome
Against
anti-S
anti-S antibody
anti-S2
anti-SARS-CoV-2 antibody
Anti-spike
antibody
Antibody Response
bidirectional
cohorts
common cold
common cold human coronaviruses (HCoVs)
coronavirus
correlated
COVID-19
cross-react
cross-reactive antibody
cross-reactive antibody response
decrease
disease
disease severity
domain
Effect
elicited
HKU1
homologous
Human
human coronavirus
IgG
IgG antibody
immune
immune imprinting.
Immunoglobulin
morbidity and mortality
Multiplex assay
OC43
Organ failure
Protective
RaTG13
recognizing
response
S proteins
S1-reactive antibodies
SARS-CoV-1
SARS-CoV-2
SARS-CoV-2 IgG
SARS-COV-2 infection
sera
serum sample
severe coronavirus disease
Severity of disease
significantly increased
SOFA
spike
strain
subject
with COVID-19
[DOI] 10.1093/infdis/jiac022 PMC 바로가기
[DOI] 10.1093/infdis/jiac022 PMC 바로가기
Early prediction of COVID-19 patient survival by targeted plasma multi-omics and machine learning
Research article
Published on
Journal: Molecular & Cellular Proteomics : MCP [Category] COVID19(2023년), SARS, 바이오마커, 변종, 진단, 치료기술,
Journal: Molecular & Cellular Proteomics : MCP [Category] COVID19(2023년), SARS, 바이오마커, 변종, 진단, 치료기술,
[키워드] BSAbovine serum albumin COVID-19
Dickinson and Company
3-nitrophenylhydrazine
AAAamino acid analysis
Accuracy
ACDacid citrate dextrose
acetonitrile
acid citrate dextrose
ACNacetonitrile
Alpha 1-antichymotrypsin
Alpha-1-antichymotrypsin
amino acid analysis
analysis of variance
ANOVAanalysis of variance
APCS
APOA2
APOA4
APOH Beta-2-glycoprotein 1
Apolipoprotein A-IIAPOA4
Apolipoprotein A-IVAPOH Beta-2-glycoprotein 1
area under the curve
AUC
AUCarea under the curve
B2MBeta-2-microglobulin
BDBecton
Becton
Beta-2-microglobulin
BHTbutylated hydroxyl toluene
bovine serum albumin COVID-19
BQC19
building
butylated hydroxyl toluene
C-reactive protein
C1RLComplement C1r subcomponent-like protein
C2Complement C2
C3Complement C3
C4AComplement C4
C4b-binding protein alpha chain
C4BPAC4b-binding protein alpha chain
C5Complement C5
C7Complement C7
C9Complement C9
CAMPCathelicidin antimicrobial peptide
capillary zone electrophoresis
Carboxypeptidase B2
Cathelicidin antimicrobial peptide
CFBComplement factor B
CFHComplement factor H
Clinical Proteomic Tumor Analysis Consortium
Coagulation factor XIII A chain
Complement C1r subcomponent-like protein
Complement C2
Complement C3
Complement C4
Complement C5
Complement C7
Complement C9
Complement factor B
Complement factor H
Concentration
concentrations
Control
COVID-19 hospitalization
COVID-19 patient
CPB2Carboxypeptidase B2
CPTACClinical Proteomic Tumor Analysis Consortium
CRPC-reactive protein
CST3Cystatin-C
Cystatin-C
CZEcapillary zone electrophoresis
disease severity
dithiothreitol
DTTdithiothreitol
ECMOextracorporeal membrane oxygenation
extracorporeal membrane oxygenation
F13A1Coagulation factor XIII A chain
FAFormic acid
false discovery rate
FDRfalse discovery rate
FGAFibrinogen alpha chain
FGBFibrinogen beta chain
FGGFibrinogen gamma chain
Fibrinogen alpha chain
Fibrinogen beta chain
Fibrinogen gamma chain
FIVE
Formic acid
Gelsolin
Gene name /Protein nameAPCS
globe
GSNGelsolin
haptoglobin
Healthcare system
Heparin cofactor 2
Hospitalization
hospitalized COVID-19 patients
HPhaptoglobin
IAAiodoacetamide
ICUIntensive Care Unit
IGFALSInsulin-like growth factor-binding protein complex acid labile subunit
Insulin-like growth factor-binding protein complex acid labile subunit
intensive care unit
Inter-alpha-trypsin inhibitor heavy chain H2
Inter-alpha-trypsin inhibitor heavy chain H4
iodoacetamide
ITIH2Inter-alpha-trypsin inhibitor heavy chain H2
ITIH4Inter-alpha-trypsin inhibitor heavy chain H4
K3EDTAtripotassium ethylenediaminetetraacetic acid
L-(tosylamido-2-phenyl) ethyl chloromethyl ketoneTrisHCl
LC-MSliquid chromatography-mass spectrometry
LC/MRM-MSliquid chromatography/multiple reaction monitoring mass spectrometry
Leucine-rich alpha-2-glycoprotein
liquid chromatography-mass spectrometry
liquid chromatography/multiple reaction monitoring mass spectrometry
LLOQLower Limit of Quantitation
Lower Limit of Quantitation
LRG1Leucine-rich alpha-2-glycoprotein
lysoPClysophosphatidylcholine
lysophosphatidylcholine
MALDImatrix assisted laser desorption ionization
mass spectrometry
matrix assisted laser desorption ionization
MeOHmethanol
metabolite
methanol
Mortality
MSmass spectrometry
N-acetylmuramoyl-L-alanine amidase
Neuropilin-2
Non-survivors
NPH3-nitrophenylhydrazine
NRP2Neuropilin-2
patient survival
PBSPhosphatase buffered saline
PCAprincipal component analysis
PCRpolymerase chain reaction
PGLYRP2N-acetylmuramoyl-L-alanine amidase
phenylisothiocyanate
Phosphatase buffered saline
PITCphenylisothiocyanate
plasma
polymerase chain reaction
post-translational modification
predict
Predictive
PRG4Proteoglycan 4
principal component analysis
PROS1Vitamin K-dependent protein S
Protein
Proteoglycan 4
PTMpost-translational modification
QCquality control
Quality control
reversed phase ultrahigh performance liquid chromatography
robust
RP-UHPLCreversed phase ultrahigh performance liquid chromatography
SAA2Serum amyloid A-1 and A-2 proteins
SAA4Serum amyloid A-4 protein
SARS-CoV-2SIS
Scientific and Cultural Organization
Sequential Organ Failure AssessmentSPE
SERPINA1Alpha-1-antichymotrypsin
SERPINA3Alpha 1-antichymotrypsin
SERPIND1Heparin cofactor 2
Serum amyloid A-1 and A-2 proteins
Serum amyloid A-4 protein
Serum amyloid P-componentAPOA2
significant difference
SIS
SOFA
solid-phase extractionSVM
SPE
stable-isotope labeled internal standardSOFA
Stratification
Support Vector MachineTPCK
survival
survivor
SVM
The Universal Protein Resource
TPCK
Transthyretin
Treatment
tripotassium ethylenediaminetetraacetic acid
Tris (hydroxymethyl) aminomethane hydrochlorideUNESCO
TrisHCl
TTRTransthyretin
UNESCO
UniProtThe Universal Protein Resource
unique
United Nations EducationalScientific and Cultural Organization
Vascular cell adhesion protein 1
VCAM1Vascular cell adhesion protein 1
Vitamin K-dependent protein S
[DOI] 10.1016/j.mcpro.2022.100277 [Article Type] Research article
[DOI] 10.1016/j.mcpro.2022.100277 [Article Type] Research article
Noninvasive ventilation in COVID-19 patients aged ≥ 70 years-a prospective multicentre cohort study
Observational Study
[키워드] 30-Day mortality
95% CI
Admission
age
assessment
Care
CFS
clinical
cohort study
COVID-19
COVID-19 pandemic
COVID-19 patient
Critically ill
death
defined
elderly
Endotracheal intubation
enrolled
Europe
European
European country
evaluate
Factor
failure
frailty
Frequency
ICU
ICU admission
IMV
intensive care
intensive care unit
International
Invasive mechanical ventilation
male
multicentre
NIV
Noninvasive ventilation
occurred
Older
outcome
Patient
patients
patients treated
primary endpoint
prospective observational study
Registered
Registration
risk
scale
severity
SOFA
the mean
treated
Ventilation
with COVID-19
[DOI] 10.1186/s13054-022-04082-1 PMC 바로가기 [Article Type] Observational Study
[DOI] 10.1186/s13054-022-04082-1 PMC 바로가기 [Article Type] Observational Study
ICU strain and outcome in COVID-19 patients-A multicenter retrospective observational study
Observational Study
[키워드] 28-day mortality
Admissions
Characteristics
Chronic kidney disease
collected
Coronavirus Disease (COVID)-19
COVID-19
COVID-19 admission
COVID-19 patient
Cox proportional-hazards model
evaluate
Factor
First wave
FIVE
France
had more
hospital
Hypoxemia
ICU
ICU admission
intensive care unit
intubation
less
management
medical records
Mortality
multicenter
multicentre
nasal
obesity
Older
Older age
outbreak
outcome
overweight
pandemic
Patient
prognosis of patient
retrospective
Retrospective study
second wave
severity
SOFA
SOFA score
study period
[DOI] 10.1371/journal.pone.0271358 PMC 바로가기 [Article Type] Observational Study
[DOI] 10.1371/journal.pone.0271358 PMC 바로가기 [Article Type] Observational Study
Major candidate variables to guide personalised treatment with steroids in critically ill patients with COVID-19: CIBERESUCICOVID study
Observational Study
[키워드] Administered
administration
affected
age
Analysis
assessment
Bacterial
baseline
benefit
Care
clinically
Corticosteroid
corticosteroid treatment
Corticosteroids
covariate
COVID-19
COVID-19 patient
Critically ill
Critically ill patient
Dexamethasone
dosage
dose
doses of corticosteroid
early administration
Evidence
failure
higher risk
hospitalisation
ICU
ICU admission
ICUs
Illness severity
in-hospital mortality
increased risk
Inflammation
information
intensive care
interaction term
Invasive mechanical ventilation
investigated
Laboratory
lower risk
Major
mechanical ventilation
Modification
Mortality
multivariable analysis
no effect
nosocomial
Observational cohort study
organ damage
Patient
patients with COVID-19
performed
personalised
Pneumonia
potential benefit
Primary outcome
Protective
receiving
severe coronavirus disease
severity
Significant
SOFA
Spanish
steroid
subgroup
subgroups
subgroups of patient
symptom onset
systemic corticosteroid
Treatment
use of corticosteroid
variable
with COVID-19
[DOI] 10.1007/s00134-022-06726-w PMC 바로가기 [Article Type] Observational Study
[DOI] 10.1007/s00134-022-06726-w PMC 바로가기 [Article Type] Observational Study
A multiplex protein panel assay for severity prediction and outcome prognosis in patients with COVID-19: An observational multi-cohort study
Research article
[키워드] accelerate
Accuracy
agency
APACHE II
assessment
Berlin
Biomarker
Biomarkers
Charité
clinical
clinical disease progression
Clinical outcome
clinical risk
clinical trials
Cohort
conducted
Council
COVID-19
COVID-19 infection
COVID-19 pandemic
COVID-19 severity
death
Dexamethasone
disease prognosis
disease severity
education
ERC
European
finding
foundation
funding
Germany
hallmark
Healthcare system
healthy individuals
help
hospitalised
introduced
LC-MS/MS
LLOQ
machine learning
median
Medicine
Mild
Mobility
moderate
multiplex
node
observational study
outcome
Patient
patient cohort
patients with COVID-19
peptide
peptides
predicted
Prognosis
Prognostic value
Protein
proteomics
quantification
Registered
registry
Research
resource
SARS-CoV2
Science
sensitivity
severe COVID-19
severity
Severity stratification
SOFA
Spectrometry
Standard of care
stratified
Support
supported
survival
System
targeted proteomics
the median
the WHO
Therapies
Treatment
Wellcome Trust
[DOI] 10.1016/j.eclinm.2022.101495 [Article Type] Research article
[DOI] 10.1016/j.eclinm.2022.101495 [Article Type] Research article