Validation of SARS-CoV-2 pooled testing for surveillance using the Panther Fusion® system: Impact of pool size, automation, and assay chemistryArticle Published on 2022-11-072022-11-15 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] approach assays authorization automated conducted cut-off threshold cycle threshold decrease demonstrated diagnostic Emergency evaluated expected FDA FIVE generate Impact less limit of detection lowering nasopharyngeal sample nucleic acid amplification positive positive sample resources SARS-CoV-2 SARS-CoV-2 RNA sensitivity specificity specimen Surveillance surveillance testing System tested validation was used [DOI] 10.1371/journal.pone.0276729 PMC 바로가기
Evaluation of the Boson rapid Ag test vs RT-PCR for use as a self-testing platformArticle Published on 2022-11-012022-11-15 Journal: Diagnostic microbiology and infectious disease [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Accuracy Antigen asymptomatic patient Boson Card COVID-19 cases COVID-19 patient COVID–19 detection rate equipment evaluate facilitate gold standard identify infected individuals Laboratory less Negative predictive value platform positive professionals Rapid rapid antigen test Real Time RT–PCR RT-PCR RT-rtPCR SARS–CoV–2 screening method Self–testing. sensitivity specificity Test the WHO time [DOI] 10.1016/j.diagmicrobio.2022.115786 PMC 바로가기
A computational approach to biological pathogenicityArticle Published on 2022-11-012022-11-15 Journal: Molecular genetics and genomics : MGG [Category] 바이오마커, [키워드] Accuracy adverse impact approach assessment Biochemistry Biomarkers clinical trial COVID-19 death Digital Digital genomic signature DNA DNA sequence energy event feature genomic Gibbs energy h-distance. Health Host humans hybridization machine machine learning machine learning model methodology microbe mitigate new strain oligonucleotide Other pandemic pathogen pathogenic Pathogenic relationship pathogenicity Pathogens/nonpathogens Perspective predict Quality reducing sensitivity Sensitivity and specificity Sickness specificity structural property [DOI] 10.1007/s00438-022-01951-w PMC 바로가기
Nucleocapsid Antigenemia Is a Marker of Acute SARS-CoV-2 InfectionArticle Published on 2022-11-012022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 바이오마커, 치료기술, [키워드] acute infection acute respiratory syndrome acute SARS-CoV-2 infection Analysis antigenemia Biomarker Blood coronavirus coronavirus disease COVID-19 determine Diagnosis ENhance exhibited Frequency highest individual Infection infection control infections Isolation nucleocapsid nucleocapsid. patients PCR polymerase chain reaction resolved retrospective RNA SARS-CoV-2 SARS-CoV-2 testing sensitivity seronegative Serosurvey severe disease specificity specimen Treatment Treatment strategies [DOI] 10.1093/infdis/jiac225 PMC 바로가기
Rapid and universal detection of SARS-CoV-2 and influenza A virus using a reusable dual-channel optic fiber immunosensorArticle Published on 2022-11-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 신종인플루엔자, 치료기술, [키워드] clinical sample colloidal gold Delta demonstrated detect dual-channel optic fiber immunosensor enzyme-linked immunosorbent Evanescent fiber H1N1 H3N2 H7N9 Infectious disease influenza A influenza A virus influenza A virus limit of detection linear mobile phase detection. much higher omicron optical pathogenic viruses platform presenting Rapid Real-time monitoring respond SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 pseudovirus sensitivity specificity Strains Surveillance TCID the epidemic the SARS-CoV-2 the spike protein variants viruses [DOI] 10.1002/jmv.28015 PMC 바로가기
Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccinationArticle Published on 2022-11-012022-11-15 Journal: Journal of Immunological Methods [Category] SARS, 진단, 치료기술, 치료제, [키워드] Antibody Response Antigen antigenic target assays correlated COVID-19 IgG immune response increasingly Infection infection with SARS-CoV-2 measure measurement multiplex Multiplex assay nucleocapsid antigen performance platform Quantitative ranged RBD Receptor binding domain S1 and S2 SARS-CoV-2 SARS-COV-2 infection sensitivity serologic assay Serologic response Serology. specificity subunit vaccination Variation [DOI] 10.1016/j.jim.2022.113345 PMC 바로가기
Diagnostic accuracy of a novel SARS CoV-2 rapid antigen test and usefulness of specimens collected from the anterior nasal cavityArticle Published on 2022-11-012022-11-15 Journal: International Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] Accuracy Ag-RDT age Antigen collected criteria cycle threshold Cycle threshold value diagnostic Diagnostic accuracy enrolled Hospitalization meet moderate nasal nasal mucosa nasopharyngeal Patient polymerase chain primary end point provide Rapid diagnostic test real-time polymerase chain reaction remained SARS CoV-2 SARS-CoV-2 sensitivity Sensitivity and specificity specificity specimen specimens utility Viral load Viral load. World Health Organization [DOI] 10.1016/j.ijid.2022.09.018 PMC 바로가기
A triple-RBD-based mucosal vaccine provides broad protection against SARS-CoV-2 variants of concernArticle Published on 2022-11-012022-11-15 Journal: Cellular and Molecular Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibodies antigenic chimeric correlated Delta effective elicit flagellin Flagellin adjuvant human ACE2 IgA immunization Infection initial intranasal intranasal immunization Lower lung mucosal mucosal vaccine Mutation nasal neutralizing antibody neutralizing immunity omicron pathology Protein provide RBD reduce SARS-CoV-2 SARS-CoV-2 variant secretory IgA significantly specificity Spread tissue pathology transgenic mice transmission potential Triple-RBD Vaccine vaccine candidate variant Variant of concern. Viral RNA [DOI] 10.1038/s41423-022-00929-3 PMC 바로가기
Comparison of SARS-CoV-2 spike antibody quantitative titer reporting using the World Health Organization International Standard Units by four commercial assaysArticle Published on 2022-11-012022-11-15 Journal: Journal of Clinical Virology [Category] SARS, 진단, [키워드] Abbott Accuracy antibodies antibody Antibody Response Antibody titer Architect BAU BNT162b2 ChAdOx1-S collected comparable correlation COVID-19 DiaSorin effective Elecsy elicited Genscript greater IgG immune response Immunoglobulin indicated individual International LIAISON Moderna mRNA-1273 naïve Neutralizing antibody titer Oxford-AstraZeneca Pfizer/BioNTech plasma protective immunity Quantitative Quantitative serological assays ranged regression analysis response Roche SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccination sensitivity seroconverted serological serological response significantly higher specificity Standard tested the WHO unit Vaccine Vaccines virus neutralization assays WHO WHO international standard. World Health Organization [DOI] 10.1016/j.jcv.2022.105292 PMC 바로가기
Oral saliva swab reverse transcription PCR for Covid-19 in the paediatric populationArticle Published on 2022-11-012022-11-16 Journal: Archives of Disease in Childhood [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] 95% CI Ag-RDT Antigen children Cohort collected COVID-19 diagnostic evaluate hospital infectious disease medicine IQR less Microbiology Molecular biology multicentre Nasopharyngeal swab NPs oral Patient performance performed positive Rapid diagnostic test reverse transcription PCR RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 testing Spain specificity Swab Symptom tested Virology Virology. younger patients [DOI] 10.1136/archdischild-2021-323712 PMC 바로가기