tissue samples – Page 2 – Communicable Diseases Research

Quantitative proteomics of hamster lung tissues infected with SARS-CoV-2 reveal host factors having implication in the disease pathogenesis and severity

SARS-CoV-2에 감염된 햄스터 폐 조직의 정량적 단백질체학은 질병 발병기전 및 중증도에 영향을 미치는 숙주 인자를 나타냅니다

Article

Published on 2021-07-012022-09-11
Journal: FASEB journal : official publication of the Federa [Category] SARS, 유전자 메커니즘,

Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19

급성 COVID-19 환자에서 설사, 대변 바이러스 RNA 및 SARS-COV-2- 특이 적 IGA에도 불구하고 제한된 장 염증

Article

Published on 2021-06-252022-09-01
Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 변종, 진단, 치료기술, 치료제,

[키워드] acute COVID-19 Antibody Response Antibody responses characterized Cohort controls COVID-19 disease COVID-19 patient COVID-19 patients Cytokines detected in stool diarrhea died difficulty Evidence evidence of fecal Gastrointestinal gastrointestinal symptoms gastrointestinal tract Gut hospitalized COVID-19 patients IgA IgA response IL-10 IL-23 IL-8 immune response individual infected individuals Infection Inflammation inflammatory markers intestinal Intestinal diseases intestinal inflammation Limited microbiome composition Mucosal immunology nasopharynx Patient SARS-CoV-2 SARS-CoV-2 RNA severe COVID-19 disease severe disease specimen Stool stool samples strain Strains survived Symptom tissue samples Translational research uninfected Viral Viral RNA
[DOI] 10.1038/s41598-021-92740-9 PMC 바로가기 [Article Type] Article

Lung histopathological findings in COVID-19 disease – a systematic review

Review

Published on 2021-05-172022-10-30
Journal: Infectious Agents and Cancer [Category] COVID-19,

[키워드] adaptive affecting alveolar alveolar cells ARDS Cell change changes Characteristics characterized clinician Comorbidity component country COVID-19 COVID-19 disease COVID-19 pandemic DAD desquamation diagnostic Diffuse alveolar damage disease endothelial epithelial evaluate Evidence hemorrhage heterogeneous histological histopathological histopathological finding Histopathology immune system Immunocompromised impacted inflammatory cells interstitial interstitial cell lung pathological mechanism pathophysiological pathway Patient proliferative respiratory supplementary material systematic review therapy tissue samples Treatment strategies type I Type II pneumocyte Vascular viral infection
[DOI] 10.1186/s13027-021-00369-0 PMC 바로가기 [Article Type] Review

Mass spectrometry-based proteomic platforms for better understanding of SARS-CoV-2 induced pathogenesis and potential diagnostic approaches

SARS-CoV-2 유도 병인 및 잠재적 진단 접근법에 대한 더 나은 이해를 위한 질량 분석 기반 단백질체 플랫폼

Review

Published on 2021-05-012022-09-11
Journal: Proteomics [Category] SARS, 유전자 메커니즘, 진단,

[키워드] AMPK applied approach Biomarkers cellular Comparative analysis comparative proteomics COVID-19 dataset diagnostic EGFR EPHA2 Ephrin functional humans in vitro experiments indicate Infection kinase kinase-substrate signaling kinases knowledge MAPK mass mass spectrometry mechanism molecular mechanism molecular mechanisms Pathogenesis pathway Pathways phosphoproteome PI3K platform post-translational modifications prognostic Protein protein targets protein-protein interaction proteome proteomic proteomics receptor SARS-CoV-2 SARS-COV-2 infection signaling pathways targeted proteomics the SARS-CoV-2 Therapeutic strategies tissue tissue sample tissue samples top-down proteomics. Viral viral infection while
[DOI] 10.1002/pmic.202000279 PMC 바로가기 [Article Type] Review

Detection of SARS‐CoV‐2 in respiratory samples from cats in the UK associated with human‐to‐cat transmission

사람에서 고양이로의 전염과 관련된 영국 고양이의 호흡기 샘플에서 SARS-CoV-2 검출

Original Research

Published on 2021-04-222022-09-10
Journal: The Veterinary Record [Category] Fulltext, MERS, SARS, 조류인플루엔자, 치료기술, 치료법,

[키워드] Analysis Antigen cats collected conjunctivitis coronavirus COVID‐19 COVID‐19 detection eight Evidence evidence of FIVE immunofluorescence infect lung tissue Mild MONITOR mutations New coronavirus nine nucleocapsid antigen nucleotide objective occurred oropharyngeal swab oropharyngeal swabs pandemic positive quantitative PCR reference sequence respiratory Respiratory disease respiratory pathogen respiratory sample Result reverse transcriptase reverse zoonosis rhinitis RNA SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 sequence Sequencing severe respiratory disease Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs submitted tested tissue tissue samples transcriptase Transmission Viral viral genome Viral RNA virus was tested
[DOI] 10.1002/vetr.247 PMC 바로가기 [Article Type] Original Research

Experimental Inoculation of Young Calves with SARS-CoV-2

SARS-CoV-2 어린 송아지 실험 접종

Article

Published on 2021-03-092022-09-10
Journal: Viruses [Category] SARS, 치료기술,

[키워드] ACE2 ACE2 receptor age analyses angiotensin angiotensin I Blood bovine calf cattle collected Course criteria determine distribution enzyme euthanasia evaluate exposure to facilitated host range implicated Infectious virus inoculated inoculation International intravenous kidney liver Lungs Lymph node nasal swab necropsy not recovered nucleic acid PCR cycle performed positive Protein Pyrexia receptor rectal swab replication of SARS-CoV-2 reported SARS-CoV-2 SARS-CoV-2 RNA Scientific community sequence Seroconversion Structural analysis susceptibility susceptible threshold tissue tissue sample tissue samples tissues tracheobronchial Urine Viral viral shedding Viremia virus was used
[DOI] 10.3390/v13030441 PMC 바로가기 [Article Type] Article

Infectivity of deceased COVID-19 patients

사망한 코로나19 환자의 감염력

Original Article

Published on 2021-03-052022-09-10
Journal: International Journal of Legal Medicine [Category] SARS, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Autopsy Cell culture Chain Reaction coronavirus coronavirus disease COVID-19 COVID-19 patient death Deceased decomposition Determination examination examined Forensic medicine group handling Infectivity interval involved Masks MOST non-infectious organ pathology Patient patients Post mortem examination Post-mortem post-mortem interval Prevent qPCR reducing respiratory respiratory tract Ribonucleic acid RNA RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe acute respiratory syndrome Coronavirus Swab swabs symptom onset tissue sample tissue samples virus isolation was performed
[DOI] 10.1007/s00414-021-02546-7 PMC 바로가기 [Article Type] Original Article

Mucosal immune responses in COVID19 – a living review

Short Communication

Published on 2021-01-252022-10-29
Journal: Oxford Open Immunology [Category] COVID-19,

Establishment of Murine Hybridoma Cells Producing Antibodies against Spike Protein of SARS-CoV-2

Article

Published on 2020-12-012022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS,

Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study

심각한 치명적인 COVID-19를 가진 영국 환자의 조직병리학적 발견 및 바이러스 친화성: 사후 연구

Article

Published on 2020-10-012022-09-11
Journal: The Lancet. Microbe [Category] SARS, 치료기술,

[키워드] Activation active viral replication acute pancreatitis acute respiratory syndrome alveolar damage aortic dissection Autopsies Autopsy Biological Biotechnology Brain Case series cause of death Clinical course Clinical data clinically Cohort Comprehensive coronavirus Council COVID-19 death description Diagnosis died diffuse Diffuse alveolar damage disseminated mucormycosis dominant eight eligible Endocarditis Evidence evidence of examined feature FIVE Genome heart high mortality rate histopathological finding histopathological findings Immune cell Immunohistochemical analysis Infarction Infection Injury IQR kidney lung lymphocyte Major major organs marantic endocarditis median age microglial Mucormycosis nine Older organ Pancreatitis Pathologists Patient patients Pericarditis Post-mortem provided Quantitative reported respiratory respiratory tract RT-PCR analysis sampling Science severe acute respiratory syndrome Coronavirus severe COVID-19 subset Support T cells thrombosis thrombotic tissue sample tissue samples transcript Viral viral genomes Viral RNA viral tropism was done Wellcome Trust
[DOI] 10.1016/S2666-5247(20)30115-4 PMC 바로가기 [Article Type] Article