Ligand-based discovery of coronavirus main protease inhibitors using MACAW molecular embeddingsArticle Published on 2023-12-012022-11-15 Journal: Journal of Enzyme Inhibition and Medicinal Chemist [Category] 치료제, [키워드] antiviral properties binding affinity cells Cheminformatics Compound compounds conducted coronavirus dataset dose-dependent inhibition drug design Drug discovery evaluate half-maximal inhibitory concentration in silico inhibitor inhibitory effect ligand-based drug design M pro machine learning machine-learning molecular protease Protease inhibitor screened selected thought Toxicity Virtual screening virus infectivity [DOI] 10.1080/14756366.2022.2132486 PMC 바로가기
Achillea millefolium : Mechanism of action, pharmacokinetic, clinical drug-drug interactions and tolerabilityReview Article Published on 2023-11-302024-09-05 Journal: Heliyon [Category] update2024, [키워드] Achillea millefolium Drug interactions mechanism of action Pharmacodynamics pharmacokinetics Toxicity [DOI] 10.1016/j.heliyon.2023.e22841 PMC 바로가기 [Article Type] Review Article
Bioinformatics analysis of multi-epitope peptide vaccines against Hepatitis C virus: a molecular docking studyarticle Published on 2023-11-142024-09-05 Journal: Journal of Genetic Engineering & Biotechnology [Category] update2024, [키워드] antigenicity CD4 CD8 Cellular responses docking scores HCV Humoral response Toxicity Vaccine development [DOI] 10.1186/s43141-023-00583-w PMC 바로가기 [Article Type] article
From oceans to dinner plates: The impact of microplastics on human healthReview Article Published on 2023-09-262024-09-05 Journal: Heliyon [Category] update2024, [키워드] COVID-19 Human exposure human health microplastics Risk assessment Toxicity [DOI] 10.1016/j.heliyon.2023.e20440 PMC 바로가기 [Article Type] Review Article
Potential Medical Use of Fullerenols After Two Decades of Oncology ResearchReview Published on 2023-09-192024-09-05 Journal: Technology in cancer research & treatment [Category] update2024, [키워드] cytostatic fullerenol oncology organ protection oxidative stress Toxicity [DOI] 10.1177/15330338231201515 PMC 바로가기 [Article Type] Review
Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapyarticle Published on 2023-08-192024-09-02 Journal: Journal of Nanobiotechnology [Category] 대상포진, [키워드] Bioavailability biocompatibility Controlled release nanomaterials Ophthalmic inflammatory diseases Targeted delivery Toxicity [DOI] 10.1186/s12951-023-01974-4 PMC 바로가기 [Article Type] article
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and agingarticle Published on 2023-08-192024-09-05 Journal: Archives of Toxicology [Category] update2024, [키워드] aging antioxidants Metals oxidative stress ROS signaling pathways Toxicity [DOI] 10.1007/s00204-023-03562-9 PMC 바로가기 [Article Type] article
Bioinformatic and literature assessment of toxicity and allergenicity of a CRISPR-Cas9 engineered gene drive to control Anopheles gambiae the mosquito vector of human malaria인간 말라리아의 모기 매개체인 Anopheles gambiae를 제어하기 위한 CRISPR-Cas9 엔지니어링 유전자 드라이브의 독성 및 알레르기성에 대한 생물정보학 및 문헌 평가Article Published on 2023-08-142024-08-01 Journal: Malaria Journal [Category] 말라리아, [키워드] allergenicity Cas9 CRISPR DsRed Environmental risk assessment (ERA) gene drive Genetically modified mosquitoes (GMM) gRNA Population suppression Toxicity [DOI] 10.1186/s12936-023-04665-5 PMC 바로가기
Toxicity of insecticidal plant oils on the larval and adult stages of a major malaria vector (Anopheles gambiae Giles 1920)article Published on 2023-05-312024-09-01 Journal: Parasitology Research [Category] 말라리아, [키워드] insecticidal malaria management Plant oils Toxicity [Article Type] article
Cell atlas of CCl 4 -induced progressive liver fibrosis reveals stage-specific responsesArticle Published on 2023-05-182024-09-05 Journal: Zoological research [Category] update2024, [키워드] Angiogenesis cell-cell interactions Gene regulatory networks Hepatic stellate cells hepatocytes Liver fibrosis Single-cell and single-nucleus RNA-sequencing Toxicity [DOI] 10.24272/j.issn.2095-8137.2023.031 PMC 바로가기 [Article Type] Article