ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions
Research Article
[키워드] ACE2
analyses
Analysis
can be used
Cell
cell line
COVID-19
COVID-19 patients
COVID-19 research
driving
explain
Express
H353K
hACE2
histological
human ACE2
identify
IFNAR
in vitro
in vivo
infect
infect cells
Infection
inflammatory disease
Inflammatory response
Inflammatory responses
Interaction
interferon response
interferon signaling
involved
key amino acid
lung
lung epithelium
mACE2
mice
Mutagenesis
no significant effect
receptor
Replication
required
rescued
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 replication
SARS-CoV-2 research
substitutions
Support
tissue repair
transcriptomic profile
transduction
type I
utility
Vaccine
Vaccines
virus
virus replication
was used
were used
[DOI] 10.1371/journal.ppat.1009723 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1009723 PMC 바로가기 [Article Type] Research Article