Fermented Carica papaya and Morinda citrifolia as Perspective Food Supplements for the Treatment of Post-COVID Symptoms: Randomized Placebo-Controlled Clinical Laboratory Study코로나 이후 증상 치료를 위한 관점 식품 보충제로서의 발효 카리카 파파야 및 모린다 시트리폴리아: 무작위 위약 대조 임상 실험실 연구Randomized Controlled Trial Published on 2022-05-252022-09-11 Journal: Nutrients [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] added addition alleviate Anti-inflammatory effects antioxidant antioxidant activity ATP Carica papaya clinical clinical laboratory clinical symptom Clinical symptoms computer tomography COVID-19 disease cytokine Cytokines delta variant disease Electrocardiography expression fermented food supplements food IL-17A IL-6 IL-8 immune Laboratory leukocyte long-lasting mechanisms metabolite microbiota Moderate COVID-19 modulating Morinda citrifolia Nitrate nitrates nitrates/nitrites nitric oxide nitrite nitrites omicron oral-nasal-pharyngeal microbiota participant Patient per day performed phagocyte phagocytosis physical physical endurance placebo group placebo-controlled polymorphonuclear leukocyte post-COVID symptoms pro-inflammatory cytokines questionnaire Randomized significantly single-center Symptoms the placebo group Treatment protocol tropical variant virus were assessed [DOI] 10.3390/nu14112203 PMC 바로가기 [Article Type] Randomized Controlled Trial
Post-COVID-19 rhino-orbito-cerebral mucormycosis: a new addition to challenges in pandemic control코로나바이러스감염증-19 이후 코뿔소-뇌-대뇌 점막진균증: 전염병 통제의 새로운 도전 과제Article Published on 2022-05-012022-09-11 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID19(2023년), SARS, 치료기술, [키워드] ± S.D addition age analyzed blurring of vision cheek close monitoring COVID COVID-19 COVID-19 symptom COVID-19 symptoms debridement demographic data Diabetic disease document endoscopic sinus surgery examination eyelid feature Features fossa headache high-risk patient High-risk patients Intervention management maxillectomy Mucor Mucormycosis nasal oxygen ophthalmoplegia Orbital apex orbital exenteration orbital pain oxygen Pain palate pandemic paranasal sinus Paranasal sinuses Patient patients presenting Prevent proptosis ptosis reduce mortality SARS-CoV-2 SARS-COV-2 infection sensation severity soft tissues specimen steroid steroid therapy surgical surgical intervention suspicion Symptoms Treatment Treatment protocol Vidian canal vision [DOI] 10.1007/s00405-021-07010-1 PMC 바로가기 [Article Type] Article
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic diseaseResearch article Published on 2022-04-012022-10-05 Journal: Medicina clínica [Category] 바이오마커, [키워드] Admission Anticoagulants approach ARDSsevere acute respiratory distress syndrome Biomarkers C-reactive protein CBCcomplete blood count chronic disease Chronic diseases complete blood count control group Coronavirus disease 2019 Corticosteroid COVID-19 COVID-19 patient COVID-19coronavirus disease 2019 CRP CRP level CRPC-reactive protein Dexamethasone diagnostic effective Effectiveness groups hematological hematological parameter identify Impact lab material mortality rate neutrophil count novel coronavirus disease Patient patients treated protocol protocols Result SARS-CoV-2severe acute respiratory syndrome coronavirus 2 severe acute respiratory distress syndrome severe acute respiratory syndrome coronavirus 2 severity significantly standard treatment statistically significant therapeutic Tocilizumab treated treating COVID-19 patient Treatment Treatment protocol was performed WBC [DOI] 10.1016/j.medcli.2022.02.013 [Article Type] Research article
The dynamics in applied COVID-19 pharmacotherapy and the influence of national guidance in The Netherlands: a quantitative and qualitative studyObservational Study Published on 2022-03-012022-10-04 Journal: European Journal of Hospital Pharmacy [Category] SARS, 임상, [키워드] Admission age analysed applied calculated collected conducted COVID-19 COVID-19 pandemic defined drug explain Guidance hospital hospitals implementation Infectious disease Local men multicentre National Netherlands Observational cohort study off-label organization and administration pandemic Patient percentage Policy practice guideline pulmonary medicine Quantitative receiving regimen specific treatment Support therapy Treatment Treatment protocol Variation Virology working [DOI] 10.1136/ejhpharm-2021-002781 PMC 바로가기 [Article Type] Observational Study
Immune Profiling of COVID-19 in Correlation with SARS and MERSReview Published on 2022-01-172022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] Adaptive immune response analyzed ARDS articles chemokine chemokines Clinical studies clinical trial coronavirus disease correlated COVID-19 COVID-19 pathogenesis cytokine Cytokine storm Cytokines death rate determine Disease diagnosis disease severity distress dosage dysregulated immune response Effect effective elevated Evidence highlight identify Immunosuppression infections inflammatory mediator information lack maintain management marker medication MERS MERS-CoV Patient profile Profiling provided regimen Research Respiratory illness responsible SARS-CoV SARS-CoV-2 SARS-CoV-2 pathogenesis shown syndrome therapeutic Treatment protocol Web of Science [DOI] 10.3390/v14010164 PMC 바로가기 [Article Type] Review
Integrative management of critical case of Covid 19 with Ayurveda and modern medicine: A case reportCase report Published on 2022-01-012022-10-05 Journal: Journal of Ayurveda and Integrative Medicine [Category] 신약개발, [키워드] age Ayurveda breathlessness Case report clinical symptom cough COVID 19 Critical Critical case dropped Health HRCT Hypothyroidism ICU Immunity integrative medicine intensive care male management medication Medicine oxygen pandemic Patient PCR performed positive provide raised Research respiratory rate Significant thalassemia treated Treatment Treatment protocol [DOI] 10.1016/j.jaim.2021.07.012 [Article Type] Case report
Genome sequencing of SARS-CoV-2 reveals the prevalence of variant B 1.1.7 in EgyptSARS-CoV-2의 게놈 시퀀싱은 이집트에서 변이 B 1.1.7의 유행을 보여줍니다Article Published on 2022-01-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome coronavirus Alpha Alpha variant authorization B 1.1.7 B.1.1.7 case fatality rates clade compatibility convalescent coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 Egypt eight Emergency expected feasibility Government Hospitalization hospitalizations majority measure Ministry of Health Monoclonal antibody treatments neutralization new SARS-CoV-2 new strain no effect outbreak Prevalence public health raised recorded respiratory reveal Sample SARS-CoV-2 SARS-CoV-2 B.1.1.7 Sequencing sera severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity shown strain susceptibility the SARS-CoV-2 transmission rate Treatment protocol Vaccine variant Viral Viral transmission [DOI] 10.1016/j.meegid.2021.105191 PMC 바로가기 [Article Type] Article
The Impact of the COVID-19 Pandemic on Cancer Care and Health-Related Quality of Life of Non-Hispanic Black/African American, Hispanic/Latina and Non-Hispanic White Women Diagnosed with Breast Cancer in the U.S.: A Mixed-Methods Study ProtocolStudy Protocol Published on 2021-12-112022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Affect Breast Breast cancer can be used Cancer cancer care cancer care disruption cancer patient Care care transitions Complete consequence contribute COVID-19 COVID-19 pandemic Critical distal ethnic and racial minorities ethnic group Evidence exacerbated Factor Health Health disparities health-related quality of life help identify Impact IMPROVE Intervention life long-term survival mixed-methods design outcomes participant Participants protocol proximal Quality Quality of life Racial resource social determinant subsequent subset Support Treatment Treatment protocol white women women’s health [DOI] 10.3390/ijerph182413084 PMC 바로가기 [Article Type] Study Protocol
Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized TrialInfectious Disease Published on 2021-11-252022-10-31 Journal: Cureus [Category] COVID-19, [키워드] addition Admission approved Azithromycin clinical Combination Comorbidities contributed correlated COVID-19 COVID-19 treatment death deficiency diabete diarrhea died disease effective Effectiveness eligibility enrolled evaluate female Future Good HCQ High dose High-dose hospital Hospital stay Hospitalization hospitalized patient Hydroxychloroquine ICU Including intensive care intravenous intravenous vitamin C IV vitamin C Lung disease Mild moderate multicenter nausea New objective Open-label Patient patient cohort patients patients with COVID-19 Probability protocol Randomized Randomly receive reducing Registered registry reported Result Safe screened Seven severe COVID-19 disease severity of symptom shown side Side effect significantly symptom severity therapy treated Treatment Treatment protocol Trial Turkey Vitamin Vitamin C Vitamin D vitamin D level vitamin D levels Vitamin D3 vomiting with COVID-19 Zinc [DOI] 10.7759/cureus.19902 PMC 바로가기 [Article Type] Infectious Disease
Computational and In Vitro Experimental Investigations Reveal Anti-Viral Activity of Licorice and Glycyrrhizin against Severe Acute Respiratory Syndrome Coronavirus 2Article Published on 2021-11-242022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] activity Affect Analysis Anti-SARS-CoV-2 Activity antiviral activity antivirals AutoDock binding affinity binding energy clinical trial Compound compounds coronavirus 2 COVID-19 COVID-19 pandemic demonstrated docked docking scores effective glycyrrhiza glycyrrhizic acid glycyrrhizin half-maximal inhibitory concentration highlight IC50 in vivo inhibited investigation licorice Ligand M pro MD simulation multiple mechanism plant Post-infection protease public health Replication respiratory robust SARS-CoV-2 SARS-CoV-2 replication Saudi Arabia screened stability Support the SARS-CoV-2 therapeutic options Treatment Treatment protocol viral infection Viral protein yielding [DOI] 10.3390/ph14121216 PMC 바로가기 [Article Type] Article