A Novel Real-Time RT-PCR-Based Methodology for the Preliminary Typing of SARS-CoV-2 Variants, Employing Non-Extendable LNA Oligonucleotides and Three Signature Mutations at the Spike Protein Receptor-Binding DomainArticle Published on 2021-09-272022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] ACE2 amino-acid amplification Analysis approach Beta blocker Delta delta variant domain Efficiency examined expand Gamma Human identify Immune escape linear LNA oligonucleotide blockers log Multiplex PCR mutated Mutation negative sample non-specific novel nucleic acid oligonucleotide other variant probe Public health interventions Rapid RBD RBM real-time RT-PCR Receptor-binding domain receptor-binding motif reduce residue resulting SARS-CoV-2 SARS-CoV-2 variant signature Spike protein Substitution TaqMan targets the SARS-CoV-2 the Spike the spike protein Transmissibility typing validation variant variant of concern variants variants of concern [DOI] 10.3390/life11101015 PMC 바로가기 [Article Type] Article
Emerging SARS-CoV-2 Diversity Revealed by Rapid Whole-Genome Sequence Typing신속한 전체 게놈 서열 타이핑으로 밝혀진 새로운 SARS-CoV-2 다양성Research Article Published on 2021-09-252022-09-10 Journal: Genome Biology and Evolution [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] Analysis analyzed average can be used changes in circulating Classifier clonal complex clone complexes COVID-19 detect Discrete Diversity ecological effective event events expansion Genome genomes genomic Genotype genotyping GISAID Hill identify Intervention lineages Local machine learning Mask mandates measure Metrics nomenclature Phylogeny Prevalence profile random Rapid replacement Revealed SARS-CoV-2 SARS-CoV-2 viral sequence Spread strain Transmission Travel typing Vaccine Variation Viral viruses Waves wgMLST whole-genome [DOI] 10.1093/gbe/evab197 PMC 바로가기 [Article Type] Research Article
Discrimination of the SARS-CoV-2 strains using of coloured s-LASCA-imaging of GB-speckles, developed for the gene “S” nucleotide sequences유전자 "S" 뉴클레오티드 서열을 위해 개발된 GB-반점의 착색된 s-LASCA 영상을 사용한 SARS-CoV-2 균주의 구별Article Published on 2021-06-252022-09-11 Journal: F1000Research [Category] SARS, 변종, 치료기술, 치료제, [키워드] approach be positive bioinformatics classical coding component demonstrated described discrimination Effectiveness GB-speckles Gene indicate LASCA molecular target natural mutation nucleotide nucleotide sequence pathogenic viruses positive processing Result resulting SARS-CoV-2 SARS–CoV-2 spike glycoprotein spike glycoprotein gene strain the SARS-CoV-2 typing variant [DOI] 10.12688/f1000research.53214.2 PMC 바로가기 [Article Type] Article
Hepatitis A Virus Strains Circulating in the Campania Region (2015–2018) Assessed through Bivalve Biomonitoring and Environmental SurveillanceArticle Published on 2020-12-232023-05-23 Journal: Viruses [Category] A형 간염, Fulltext, [키워드] bivalves HAV hepatitis A PCR Sequencing sewage typing [DOI] 10.3390/v13010016 PMC 바로가기 [Article Type] Article
Spike protein D614G and RdRp P323L: the SARS-CoV-2 mutations associated with severity of COVID-19Original Article Published on 2020-12-072022-11-01 Journal: Genomics & Informatics [Category] COVID-19, [키워드] acute respiratory syndrome affected aligned caused coronavirus coronavirus disease COVID-19 COVID-19 patient D614G database detective disease severity downloaded Frequency Genome genome sequence genomic sequence GISAID groups help initiative mutant Mutation mutations non-coding region P323L P323L mutation Patient pneumonia virus profile Protein RdRP reference sequence required resulting RNA-dependent RNA polymerase SARS-CoV-2 sequence severity severity of COVID-19 Severity of disease silent spike Spike protein spike protein D614G statistically significant the SARS-CoV-2 typing variant Wuhan [DOI] 10.5808/GI.2020.18.4.e44 PMC 바로가기 [Article Type] Original Article
Peripheral blood inflammatory markers in predicting prognosis in patients with COVID‐19. Some differences with influenza ACOVID-19 환자의 예후를 예측하는 말초 혈액 염증 마커. A형 인플루엔자와의 몇 가지 차이점Research Article Published on 2020-11-222022-08-31 Journal: Journal of Clinical Laboratory Analysis [Category] MERS, 바이오마커, [키워드] AST AUC Blood clinical Clinical data correlation COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 CREA D‐dimer Data collection electronic medical record enrolled evaluate forms hematologic hospital hsCRP IL‐6 individual Inflammation Inflammatory marker inflammatory markers Influenza influenza A intensity Local medical records Mild NLR Patient patients peripheral Peripheral blood positive correlation positive correlations predict Prognosis reflected Result SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 virus SARS‐CoV‐2 sensitivity severity significantly SII specificity typing worse prognosis Wuhan [DOI] 10.1002/jcla.23657 PMC 바로가기 [Article Type] Research Article
Impact of COVID-19 pandemic and the lockdown on invasive meningococcal diseaseResearch Note Published on 2020-08-272022-10-27 Journal: BMC Research Notes [Category] COVID-19, MERS, [키워드] addressed association correlation COVID-19 COVID-19 pandemic described disease Enhancing flu French Haemophilus influenzae Impact Infection invasive Invasive meningococcal disease involved isolate isolates lockdown mandatory National Reference Centre objective Respiratory presentations Result SARS-CoV-2 SARS-CoV-2, COVID-19 Secondary bacterial infections significantly increased Surveillance These data typing vaccination [DOI] 10.1186/s13104-020-05241-9 PMC 바로가기 [Article Type] Research Note
Letter to the editor: importance of a careful investigation to avoid attributing Legionnaires’ disease cases to an incorrect source of infectionLetter Published on 2020-08-272022-10-31 Journal: Eurosurveillance [Category] Coronavirus, Fulltext, MERS, [키워드] disease epidemiological and environmental investigation Legionella Legionnaires disease source of infection typing [DOI] 10.2807/1560-7917.ES.2020.25.34.2001484 PMC 바로가기 [Article Type] Letter
Nine-Year Nationwide Environmental Surveillance of Hepatitis E Virus in Urban Wastewaters in Italy (2011–2019)Article Published on 2020-03-202023-05-25 Journal: International Journal of Environmental Research an [Category] E형 간염, Fulltext, [키워드] hepatitis E virus PCR Prevalence Sequencing sewage typing [DOI] 10.3390/ijerph17062059 PMC 바로가기 [Article Type] Article
Quantification and genetic diversity of Hepatitis E virus in wild boar (Sus scrofa) hunted for domestic consumption in Central ItalyArticle Published on 2019-09-012023-06-11 Journal: Food microbiology [Category] E형 간염, [키워드] foodborne transmission hepatitis E virus HEV Risk assessment typing Wild boar [DOI] 10.1016/j.fm.2019.02.005