Past COVID-19 and immunosuppressive regimens affect the long-term response to anti-SARS-CoV-2 vaccination in liver transplant recipients과거의 COVID-19 및 면역억제 요법은 간 이식 수혜자의 항 SARS-CoV-2 백신 접종에 대한 장기 반응에 영향을 미칩니다Article Published on 2022-07-012022-09-11 Journal: Journal of hepatology [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] Affect anti-RBD anti-receptor-binding domain anti-SARS-CoV-2 anti-SARS-CoV-2 vaccination anti-SARS-CoV-2 vaccine anti-SARS-CoV-2 vaccines Antibody Response Antibody titer ascites baseline BNT162b2 BNT162b2 vaccine Control controls COVID-19 COVID-19 recovered patient daily dose dose effective enrolled Frequency IgG IgG antibody immunogenicity immunosuppressive independent predictor independent predictors less leukocyte liver liver transplant Liver transplantation median MMF mRNA mRNA vaccine mycophenolate mycophenolate mofetil naïve negative controls negativity patients positive Protein recipient recipients regimen second vaccination serum significantly lower tested U/mL vaccination vaccine dose [DOI] 10.1016/j.jhep.2022.02.015 PMC 바로가기 [Article Type] Article
Serosurveillance after a COVID-19 vaccine campaign in a Swiss police cohort스위스 경찰 집단에서 COVID-19 백신 캠페인 후 혈청 감시Article Published on 2022-07-012022-09-11 Journal: Immunity, Inflammation and Disease [Category] 치료법, [키워드] age anti-NCP-antibodies anti-S antibody anti-S-antibodies. anti-spike antibody antibody Antibody titer association baseline calculated Cohort Comorbidity COVID-19 COVID-19 seroprevalence COVID-19 vaccine cross-sectional demonstrated Department Follow-up visit General population had no healthcare professionals Infection infection rate male nucleocapsid protein online questionnaires participant performed reported resulting risk SARS-CoV-2 Seroconversion Seroprevalence Spike protein study participant Study participants study population These data U/mL vaccination vaccination rate vaccination rates vaccine dose was performed [DOI] 10.1002/iid3.640 PMC 바로가기 [Article Type] Article
Antibody Response Induced by BNT162b2 and mRNA-1273 Vaccines against the SARS-CoV-2 in a Cohort of Healthcare Workers의료 종사자 집단에서 SARS-CoV-2에 대한 BNT162b2 및 mRNA-1273 백신에 의해 유도된 항체 반응Article Published on 2022-06-072022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] age analyzed anti-S antibodies antibody Antibody Response Arterial hypertension BMI BNT162b2 body mass body mass index clinical clinical variables Cohort confounders confounding factors Elecsy Elecsys healthcare Healthcare workers humoral immunogenicity hypertension individual induced infected with SARS-CoV-2 Infection levels of antibody lowest medians mRNA mRNA vaccine mRNA vaccines mRNA-1273 mRNA-1273 vaccine N protein non-infected nucleocapsid preserved Protein response Roche Diagnostics S protein SARS-CoV-2 SARS-COV-2 infection serology serum sample serum samples smoking subject subjects Switzerland the antibody response the S protein the SARS-CoV-2 U/mL uninfected vaccination Vaccine variable worker [DOI] 10.3390/v14061235 PMC 바로가기 [Article Type] Article
Salivary antibodies are detected with a commercial anti-SARS-CoV-2 assay only after two doses of vaccine using serum thresholds타액 항체는 혈청 역치를 사용하여 백신을 2회 접종한 후에만 상용 항-SARS-CoV-2 분석으로 검출됩니다.Article Published on 2022-06-012022-09-11 Journal: Clinical biochemistry [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Anti-spike antibody antibody assay BNT162b2 BNT162b2 vaccine Cohort collected convalescent COVID-19 patient COVID-19 COVID-19 serology declined detect dose feasibility first dose Matched nucleic acid of BNT162b2 Pfizer-BioNTech Quantitative receiving Roche Diagnostics Saliva saliva samples salivary SARS-CoV-2 second dose serology serum Serum level serum levels single dose specimen Surveillance tested These data threshold thresholds Total U/mL vaccination Vaccine vaccine dose Volunteer [DOI] 10.1016/j.clinbiochem.2022.02.002 PMC 바로가기 [Article Type] Article
A case series of severe breakthrough infections observed in nine patients with COVID-19 in a southwestern German university hospital독일 남서부 대학 병원에서 9명의 COVID-19 환자에서 관찰된 일련의 심각한 돌발 감염 사례Article Published on 2022-06-012022-09-11 Journal: Infection [Category] COVID19(2023년), SARS, 변종, [키워드] addition advanced age age analyzed avoidance B.1.617.2 behavioural BNT162b2 BNT162b2 vaccines booster vaccination Breakthrough infection cardiorespiratory case sery Comorbidities Complete Course COVID-19 death delta variant disease dose effective Face masks FIVE high risk high-risk area high-risk areas Hospitalization Hospitalized hospitalized patient immunization Increased Infection Intensive intensive care lack measure Measures median median age nine of BNT162b2 Patient patients patients died patients with COVID-19 Pfizer-BioNTech preventive measures Protective question raise risk factor Risk factors SARS-CoV-2 suffered symptom onset Travel two patients U/mL university hospital vaccination Vaccine Vaccine breakthrough [DOI] 10.1007/s15010-022-01797-9 PMC 바로가기 [Article Type] Article
Antibody response to mRNA SARS-CoV-2 vaccination in 182 patients after allogeneic hematopoietic cell transplantation동종 조혈 세포 이식 후 182명의 환자에서 mRNA SARS-CoV-2 백신 접종에 대한 항체 반응Article Published on 2022-06-012022-09-12 Journal: Transplant infectious disease : an official journa [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Allogeneic Allogeneic hematopoietic cell transplantation Antibody titer asked Care Cell cell transplantation Characteristics complications disease Elecsy evaluate evaluated excluded Factor follow-up visits high risk identify immune immunosuppressive infection with SARS-CoV-2 initial Lymphocyte count majority malignancy mRNA mRNA vaccination mRNA vaccine Patient patient cohort patients post-transplant care. Previous studies proportion risk factor Roche SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination Sex significantly Stem cell transplantation therapy Treatment trials U/mL underlying disease vaccination vaccination efficacy was measured while [DOI] 10.1111/tid.13828 PMC 바로가기 [Article Type] Article
Peak value of serum KL-6 may be useful for predicting poor prognosis of severe COVID-19 patients혈청 KL-6의 피크 값은 심각한 COVID-19 환자의 나쁜 예후를 예측하는 데 유용할 수 있습니다Observational Study Published on 2022-05-192022-09-11 Journal: European Journal of Medical Research [Category] MERS, 바이오마커, 임상, [키워드] 95% CI Accuracy adjusted odds ratio Admission age alveolar Analysis analyzed Area AUC baseline characteristics best Biomarker Biomarkers Comorbidities Concentration COVID-19 COVID-19 patient COVID-19 patients criteria cut-off value defined determine discrimination early phase epithelial evaluate examination help high risk high-flow oxygen therapy higher risk Hospitalization hospitalized patient identify inclusion criteria indicated initial Injury Invasive mechanical ventilation KL-6 LDH Logistic regression analyses minimum multivariate logistic regression non-survivor observational study once a week oxygen Oxygen therapy Patient patients peak performed Pneumonitis poor prognosis predict Prognosis Prognostic value progression reflect reported required Respiratory failure retrospective sensitivity serum severe COVID-19 patient Sex single-center supplemental oxygen survivor Treatment U/mL [DOI] 10.1186/s40001-022-00690-3 PMC 바로가기 [Article Type] Observational Study
Response to three doses of the Pfizer/BioNTech BNT162b2 COVID-19 vaccine: a retrospective study of a cohort of haemodialysis patients in France화이자/바이오엔텍 BNT162b2 코로나19 백신 3회 투여에 대한 반응: 프랑스 혈액투석 환자 집단에 대한 후향적 연구Observational Study Published on 2022-05-182022-09-12 Journal: BMC Nephrology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] Anti-spike blood sample BNT162b2 body mass index booster Clinical practice Cohort Comirnaty coronavirus disease COVID-19 defined dialysis dose Factor France French Haemodialysis humoral humoral immune response identify IgG Immunoglobulin injection Injections kidney mortality rate mRNA vaccine National non-responder of BNT162b2 Patient patients performed Pfizer/BioNTech receive Registered remained Responder response retrospective Retrospective study SARS-CoV-2 serological serum albumin significantly significantly higher study population the mean the median titre U/mL Vaccine vaccine doses venous [DOI] 10.1186/s12882-022-02751-5 PMC 바로가기 [Article Type] Observational Study
Quantitative Detection of Anti-SARS-CoV-2 Antibodies Using Indirect ELISA간접 ELISA를 사용한 항-SARS-CoV-2 항체의 정량적 검출Article Published on 2022-05-052022-09-11 Journal: Laboratory medicine [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] albumin Antibody detection Blood Chain Reaction characteristic COVID-19 cutoff value detection determine determined by diagnosis of COVID-19 dried blood ELISA ELISA assay enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay gold gold standard iELISA IgA IgA antibodies IgA antibody IgG IgM material N protein N proteins nucleocapsid nucleocapsid protein outbreak Patient plasma polymerase chain reaction real-time reverse transcription-polymerase chain reaction receiver operating characteristic Receptor binding domain remained S1 RBD SARS-CoV-2 sensitivity Seroprevalence serum serum/plasma serum/plasma. specificity specimen Spread subunit the disease U/mL vaccinated individuals virus [DOI] 10.1093/labmed/lmab085 PMC 바로가기 [Article Type] Article
Antibody response to the COVID-19 ChAdOx1nCov-19 and BNT162b vaccines after temporary suspension of DMARD therapy in immune-mediated inflammatory disease (RESCUE)면역매개염증질환(RESCUE)에서 DMARD 치료를 일시적으로 중단한 후 COVID-19 ChAdOx1nCov-19 및 BNT162b 백신에 대한 항체 반응Randomized Controlled Trial Published on 2022-05-012022-09-11 Journal: RMD Open [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] Adult patients Antibody Response Antibody responses antirheumatic agents AstraZeneca AZ vaccine baseline biologic BNT162b Control control group control groups controls COVID-19 csDMARD dose Final first and second dose first dose first vaccination group groups IgG Immune-mediated immunogenicity inflammatory disease Messenger RNA multicentre not significantly different Patient Pfizer Protein randomised randomised controlled trial registration number response S1/S2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV2 second dose second vaccination Seroconversion seroconversion rate seroconversion rates significantly lower the antibody response the mean therapy titre titres U/mL vaccination Vaccine were measured [DOI] 10.1136/rmdopen-2022-002301 PMC 바로가기 [Article Type] Randomized Controlled Trial