Virus neutralisation – Page 2 – Communicable Diseases Research

Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases

중증, 중등도 및 경증 COVID-19 사례의 회복기 샘플에서 SARS-CoV-2 감염의 혈청학적 바이오마커 분석

Comparative Study

Published on 2021-11-192022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 변종, 진단, 치료기술, 치료법,

COVID-19 outbreak among French firefighters, Marseille, France, 2020

2020년 프랑스 마르세유에서 프랑스 소방관들 사이에서 COVID-19 발생

Outbreaks

Published on 2021-10-142022-09-10
Journal: Eurosurveillance [Category] MERS, SARS, 치료기술,

Head-to-head evaluation of seven different seroassays including direct viral neutralisation in a representative cohort for SARS-CoV-2

SARS-CoV-2에 대한 대표적인 코호트에서 바이러스 직접 중화를 포함한 7가지 혈청 분석에 대한 일대일 평가

Animal

Published on 2021-10-082022-09-10
Journal: The Journal of General Virology [Category] MERS, SARS, 진단, 치료법,

Neutralising SARS-CoV-2 RBD-specific antibodies persist for at least six months independently of symptoms in adults

Research

Published on 2021-07-142022-10-05
Journal: Communications Medicine [Category] 진단,

Prevalence and incidence of anti-SARS-CoV-2 antibodies among healthcare workers in Belgian hospitals before vaccination: a prospective cohort study

예방접종 전 벨기에 병원 의료진 중 항SARS-CoV-2 항체 유병률 및 발생률: 전향적 코호트 연구

Multicenter Study

Published on 2021-06-292022-09-11
Journal: BMJ Open [Category] SARS, 치료기술,

[키워드] 95% CI age All participants anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Characteristics cohort study collected compatible symptoms Contact contact with COVID-19 detect effective eligible ELISA Epidemiology Euroimmun Evolution Follow-up HCW healthcare worker hospital hospitals IgG immunology incidence Infection infection control Infection prevention involved measure median age nasopharyngeal swabs neutralisation test Neutralising Antibodies neutralising antibody Nurse participant Participants Patient Physicians positive Prevalence Prevention and control Prospective prospective cohort study public health qPCR questionnaire Randomly Real-time reverse transcription PCR registration number remained reported reverse transcription PCR RT-qPCR SARS-CoV-2 selected Seroconversion seroconverted seronegative seronegative participant seropositive individuals seropositive samples Seroprevalence serum Symptom Vaccination strategy Virus neutralisation was performed was used were measured women
[DOI] 10.1136/bmjopen-2021-050824 PMC 바로가기 [Article Type] Multicenter Study

Inclusion of cGAMP within virus‐like particle vaccines enhances their immunogenicity

바이러스 유사 입자 백신에 cGAMP를 포함하면 면역원성이 향상됩니다.

Article

Published on 2021-06-182022-09-12
Journal: EMBO Reports [Category] MERS, SARS, 진단,

[키워드] accompanied activate Administered Antibody titre antibody titres Antigen antigens CD4 CD8 T‐cell Cell cells cGAMP cyclic doses ENhance follicular Gag glycoprotein G Haemagglutinin immunology immunostimulatory Inclusion increase induce influenza A virus Methods & Resources mice Microbiology, Virology & Host Pathogen Interaction neutralising antibody Particle Particles platform produced Protein reduced responses SARS‐CoV‐2 spike SARS‐CoV‐2 titre type I interferon vaccination Vaccine vector vesicular stomatitis virus viral vaccine vector virus Virus neutralisation virus particle VLP VLPs
[DOI] 10.15252/embr.202152447 PMC 바로가기 [Article Type] Article

Convalescent plasma therapy in patients with moderate-to-severe COVID-19: A study from Indonesia for clinical research in low- and middle-income countries

Research article

Published on 2021-06-042022-10-05
Journal: EClinicalMedicine [Category] 임상,

[키워드] administration antibody baseline blueprint clinical Clinical improvement comparable convalescent plasma coronavirus country COVID-19 detectable development disease disease stage Donor dose finding funding Good highlight improvement Indonesia interval investigated Laboratory parameters Low- and middle-income countries median Mild moderate Most patient NAb NAbs outcome Patient patients with moderate plasma randomised controlled trial recruited reduction Registered required Research SARS-CoV-2 severe coronavirus disease severe disease severe;LMIC supported therapy transfused Treatment Trial variable virus Virus neutralisation were measured World Health Organization
[DOI] 10.1016/j.eclinm.2021.100931 [Article Type] Research article

Limited specificity of commercially available SARS-CoV-2 IgG ELISAs in serum samples of African origin

아프리카 기원의 혈청 샘플에서 상업적으로 이용 가능한 SARS-CoV-2 IgG ELISA의 제한된 특이성

Article

Published on 2021-06-012022-09-11
Journal: Tropical medicine & international health : TM & IH [Category] MERS, SARS, 진단, 치료법,

[키워드] Africa African analysed Antigen binding collected common cold common cold CoV common cold CoVs country COVID-19 COVID-19 pandemic CoVs diagnostics Donor elicited ELISA ELISAs Endemic enzyme enzyme-linked immunosorbent assay Euroimmun Europe Germany house IgG IgG antibodies IgG antibody immune response immune responses Immunoglobulin Immunoglobulin G Infection inhibit Interference Limited mandatory much lower Nigeria novel Novel coronavirus nucleocapsid OC43 parasites pathogen Pathogens Population positive protocol reduced SARS-CoV-2 SARS-CoV-2 IgG sera Seroepidemiologic studies serological test Serological tests serum serum sample serum/plasma significantly South America Specific Specificities specificity virus Virus neutralisation viruses
[DOI] 10.1111/tmi.13569 PMC 바로가기 [Article Type] Article

Comparison of Serological Assays for the Detection of SARS-CoV-2 Antibodies

SARS-CoV-2 항체 검출을 위한 혈청학적 분석법의 비교

Comparative Study

Published on 2021-04-202022-09-01
Journal: Viruses [Category] MERS, SARS, 진단, 치료기술,

[키워드] Antibody detection Antibody Response Antibody test antibody tests biosafety biosafety level Cohort Combination convalescent convalescent plasma coronavirus correlated strongly correlation COVID-19 COVID-19 patient cross-reactivity detect detection detection rate diagnostic discrimination Efficiency ELISA ENhance exposure to healthy individual healthy individuals hospital humans IgG IgG ELISA Infection infection with COVID-19 lentivirus neutralisation test neutralization positive provided pseudotype neutralisation Research SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 pseudotype virus SARS-CoV-2 virus SARS-CoV-2-N Screen sensitivities sensitivity serological serum severe disease spike glycoproteins utility Virus neutralisation VNT was performed
[DOI] 10.3390/v13040713 PMC 바로가기 [Article Type] Comparative Study

Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients: An observational cohort study

입원한 COVID-19 환자에서 SARS-CoV-2에 대한 항체의 일시적 발달 및 중화 가능성: 관찰 코호트 연구

Observational Study

Published on 2021-01-262022-09-10
Journal: PLoS ONE [Category] 임상, 진단, 치료기술, 치료법,

[키워드] ACE-2 antibody Antibody Response Antibody responses attachment protein best binding clinical presentation Cohort COVID-19 description diagnostic diagnostic testing domain event explain Frame help hospitalised hospitalised COVID-19 patient hospitalised COVID-19 patients house human host Humoral response humoral responses IgG antibodies IgG antibody IgG response IgG responses Infection inhibiting binding neutralising nucleocapsid protein Observational cohort study onset of symptoms outcome Patient predictor produced Protective Protein RBD reached receptor respiratory respiratory infection S protein SARS-CoV-2 Seroconversion seroconverting Serological assay serological assays symptom onset Temporal the S protein These data Time frame unit Viral viral respiratory infection Virus neutralisation were used
[DOI] 10.1371/journal.pone.0245382 PMC 바로가기 [Article Type] Observational Study